Zobrazeno 1 - 10 of 105 pro vyhledávání: '"Marco, Bocola"'
1
Akademický článek
2-Methyl-2,4-pentanediol (MPD) boosts as detergent-substitute the performance of ß-barrel hybrid catalyst for phenylacetylene polymerization
Autor: Julia Kinzel, Daniel F. Sauer, Marco Bocola, Marcus Arlt, Tayebeh Mirzaei Garakani, Andreas Thiel, Klaus Beckerle, Tino Polen, Jun Okuda, Ulrich Schwaneberg
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 1498-1506 (2017)
Covering hydrophobic regions with stabilization agents to solubilize purified transmembrane proteins is crucial for their application in aqueous media. The small molecule 2-methyl-2,4-pentanediol (MPD) was used to stabilize the transmembrane protein
Externí odkaz: https://doaj.org/article/003cdb77b4df49c9aa069f525662acb6
Zobrazit plný text záznamu
2
Akademický článek
Bifunctional CYP81AA proteins catalyse identical hydroxylations but alternative regioselective phenol couplings in plant xanthone biosynthesis
Autor: Islam El-Awaad, Marco Bocola, Till Beuerle, Benye Liu, Ludger Beerhues
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Xanthones are pharmacologically and biosynthetically intriguing compounds. Here, the authors identify two cytochrome P450 enzymes, which hydroxylate and cyclize the benzophenone precursor to either 1,3,7- or 1,3,5-trihydroxyxanthones, and pinpoint re
Externí odkaz: https://doaj.org/article/24ea258c94a0425394112027bfe0fec6
Zobrazit plný text záznamu
4
A novel epitope-presenting thermostable scaffold for the development of highly specific insulin-like growth factor-1/2 antibodies
Autor: Michael Schräml, Marco Bocola, Sabine Goller, David Casagolda, Hartmut Düfel, Heidi Klöppel-Swarlik, Christian Scholz, Leopold Von Proff, Carmen Peeß, Alessandra Hoppe, Michael Gerg, Frank Kowalewsky
Publikováno v: The Journal of Biological Chemistry
High sequence and structural homology between mature human insulin-like growth factors IGF-1 and IGF-2 makes serological discrimination by immunodiagnostic IGF tests a challenging task. There is an urgent need for highly specific IGF-1 and IGF-2 anti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e4409abb260a872fff86fe6cdcfe86
https://doi.org/10.1074/jbc.ra119.007654
Zobrazit plný text záznamu
5
Computer-aided directed evolution ofl-threonine aldolase for asymmetric biocatalytic synthesis of a chloramphenicol intermediate
Autor: Baoqin Cai, Marco Bocola, Ameng Zhou, Fenshuai Sun, Qing Xu, Jiadong Yang, Tianran Shen, Zhaoqi Zhang, Lei Sun, Yaoyao Ji, Yong Koy Bong, Thomas Daussmann, Haibin Chen
Publikováno v: Bioorganic & Medicinal Chemistry. 68:116880
l-Threonine aldolases (LTAs) employing pyridoxal phosphate (PLP) as cofactor can convert low-cost achiral substrates glycine and aldehyde directly into valuable β-hydroxy-α-amino acids such as (2R,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl) propanoic a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165c16a4460c522d2500efea3f3a21c9
https://doi.org/10.1016/j.bmc.2022.116880
Zobrazit plný text záznamu
6
Applied biocatalysis beyond just buffers : from aqueous to unconventional media. Options and guidelines
Autor: Dörte Rother, Marco Bocola, Morten M. C. H. van Schie, Pablo Domínguez de María, Jan-Dirk Spöring
Publikováno v: Green chemistry 23, 3191-3206 (2021). doi:10.1039/D1GC00561H
Green Chemistry
Green chemistry : GC 23(9), 3191-3206 (2021). doi:10.1039/D1GC00561H
In nature, enzymes conventionally operate under aqueous conditions. Because of this, aqueous buffers are often the choice for reaction media when enzymes are applied in chemical synthesis. However, to meet the demands of an industrial application, du
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf1a9d708a4e88aa783440ed295fac4
Zobrazit plný text záznamu
7
Reversal of Regioselectivity in Zinc-Dependent Medium-Chain Alcohol Dehydrogenase from Rhodococcus erythropolis toward Octanone Derivatives
Autor: Mehdi D. Davari, Anna Gärtner, Gaurao V. Dhoke, Dinc Yasat Hacibaloglu, Marco Bocola, Yunus Ensari, Anna Joëlle Ruff
Publikováno v: ChemBioChem : a European journal of chemical biology 21(20), 2957-2965 (2020). doi:10.1002/cbic.202000247
Chembiochem
The zinc‐dependent medium‐chain alcohol dehydrogenase from Rhodococcus erythropolis (ReADH) is one of the most versatile biocatalysts for the stereoselective reduction of ketones to chiral alcohols. Despite its known broad substrate scope, ReADH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68408a747226d75615116d836da37f59
Zobrazit plný text záznamu
8
How to engineer glucose oxidase for mediated electron transfer
Autor: Marco Bocola, Hartmut Duefel, Anne-Maria Wallraf, Mehdi D. Davari, Thomas Meier, Erik Arango Gutierrez, Alexandra Balaceanu, Ulrich Schwaneberg
Publikováno v: Biotechnology and Bioengineering. 115:2405-2415
Glucose oxidase (GOx) is of high industrial interest for glucose sensing because of its high β-d-glucose specificity. The efficient and specific electrochemical communication between the redox center and electrodes is crucial to ensure accurate gluc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e464bb16bd33924d04c7b1f3c9d63e3
https://doi.org/10.1002/bit.26785
Zobrazit plný text záznamu
9
Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis
Autor: Alexander R. Grimm, Leilei Zhu, Mehdi D. Davari, Jun Okuda, Marco Bocola, Akira Onoda, Shunsuke Kato, Ulrich Schwaneberg, Daniel F. Sauer, Takashi Hayashi
Publikováno v: ACS Catalysis. 8:3358-3364
Incorporation of a synthetic metal catalyst into a protein scaffold yields a biohybrid catalyst, with a remarkable performance in aqueous media and the broad reaction scope of organometallic catalysts. A major challenge for efficient catalysis is the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f76faba47bfa72f6cdca4aea27dc1a09
https://doi.org/10.1021/acscatal.7b03652
Zobrazit plný text záznamu
10
Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase
Autor: Jochen Mueller-Dieckmann, Ulrich Schwaneberg, Saravanan Panneerselvam, Aamir Shehzad, Matthias Wilmanns, Marco Bocola, Mehdi D. Davari
Publikováno v: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1866:134-140
P450 BM3 is a multi-domain heme-containing soluble bacterial monooxygenase. P450 BM3 and variants are known to oxidize structurally diverse substrates. Crystal structures of individual domains of P450 BM3 are available. However, the spatial organizat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f2936d9a1ca6a2dcb7bf43aa298ba5
https://doi.org/10.1016/j.bbapap.2017.07.010
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje