Zobrazeno 1 - 10
of 435
pro vyhledávání: '"Marco, Alifano"'
Autor:
Riccardo Orlandi, Lorenzo Gherzi, Michele Ferrari, Giovanni Mattioni, Marco Alifano, Alessandro Pardolesi
Publikováno v:
Surgical Techniques Development, Vol 13, Iss 3, Pp 269-277 (2024)
Background: anatomic lung segmentectomies allow accurate resection of pulmonary lesions, maximizing healthy tissue preservation, and reducing unnecessary loss of lung function. In this setting, accurate preoperative planning is crucial. We present ou
Externí odkaz:
https://doaj.org/article/9d89f2194baf4f7b9c0b112eff4286bf
Publikováno v:
JTCVS Open, Vol 20, Iss , Pp 194-201 (2024)
Objectives: Reprogramming of energy metabolism is a well-established hallmark of cancer, with aerobic glycolysis classically considered a prominent feature. We investigate the heterogeneity in glucose metabolism pathways within resectable primary lun
Externí odkaz:
https://doaj.org/article/8ece32145c714ff1aa2b1ce79fe04e9f
Comparison of juvenile and adult myasthenia gravis in a French cohort with focus on thymic histology
Autor:
Frédérique Truffault, Ludivine Auger, Nadine Dragin, Jean-Thomas Vilquin, Elie Fadel, Vincent Thomas de Montpreville, Audrey Mansuet-Lupo, Jean-François Regnard, Marco Alifano, Tarek Sharshar, Anthony Behin, Bruno Eymard, Francis Bolgert, Sophie Demeret, Sonia Berrih-Aknin, Rozen Le Panse
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Myasthenia gravis (MG) is an autoimmune disease characterized by muscle fatigability due to acetylcholine receptor (AChR) autoantibodies. To better characterize juvenile MG (JMG), we analyzed 85 pre- and 132 post-pubescent JMG (with a cutoff
Externí odkaz:
https://doaj.org/article/3b000a0cb9d84470876edb122fb42735
Autor:
Luca Simula, Mattia Fumagalli, Lene Vimeux, Irena Rajnpreht, Philippe Icard, Gary Birsen, Dongjie An, Frédéric Pendino, Adrien Rouault, Nadège Bercovici, Diane Damotte, Audrey Lupo-Mansuet, Marco Alifano, Marie-Clotilde Alves-Guerra, Emmanuel Donnadieu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract The ability of CD8+ T cells to infiltrate solid tumors and reach cancer cells is associated with improved patient survival and responses to immunotherapy. Thus, identifying the factors controlling T cell migration in tumors is critical, so t
Externí odkaz:
https://doaj.org/article/643fa17256824db689f9eb5d26b03503
Autor:
Lucia Parlati, Mehdi Sakka, Aurelia Retbi, Samir Bouam, Lamia Hassani, Jean-François Meritet, Pierre Rufat, Dominique Bonnefont-Rousselot, Rui Batista, Benoit Terris, Agnès Bellanger, Dominique Thabut, Aurore Vozy, Jean-Philippe Spano, Romain Coriat, François Goldwasser, Selim Aractingi, Philippe Sogni, Stanislas Pol, Vincent Mallet, Jérôme Alexandre, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Sixtine De Percin, Nora Kramkimel, Olivier Huillard, Jeanne Chapron, Benedicte Deau-Fischer, Marie-Laure Brandely-Piat, Diane Damotte, Audrey Lupo, Marco Alifano, Marion Corouge, Clémence Hollande, Hélène Fontaine, Lorianne Lair Mehiri, Anaïs Vallet Pichard, Patrick Tilleul
Publikováno v:
JHEP Reports, Vol 5, Iss 12, Pp 100880- (2023)
Background & Aims: There is concern about the burden of liver injury in patients with cancer exposed to immune checkpoints inhibitors (ICIs). Methods: In a retrospective cohort study, we evaluated the likelihood of grade 3/4 liver injury, of grade 3/
Externí odkaz:
https://doaj.org/article/788878b251bf4c95a2f7143042e64143
Autor:
José A. Villegas, Jérôme Van Wassenhove, Judith Merrheim, Karen Matta, Samy Hamadache, Clémence Flaugère, Pauline Pothin, Frédérique Truffault, Sébastien Hascoët, Nicola Santelmo, Marco Alifano, Sonia Berrih-Aknin, Rozen le Panse, Nadine Dragin
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Acetylcholine receptor (AChR) myasthenia gravis (MG) is a chronic autoimmune disease characterized by muscle weakness. The AChR+ autoantibodies are produced by B-cells located in thymic ectopic germinal centers (eGC). No therapeutic approach
Externí odkaz:
https://doaj.org/article/6ac36ee824704895ac0fbb4a9f498d11
Autor:
Priyanka Devi-Marulkar, Solène Fastenackels, Pierre Karapentiantz, Jérémy Goc, Claire Germain, Hélène Kaplon, Samantha Knockaert, Daniel Olive, Marylou Panouillot, Pierre Validire, Diane Damotte, Marco Alifano, Juliette Murris, Sandrine Katsahian, Myriam Lawand, Marie-Caroline Dieu-Nosjean
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Regulatory T cells (Tregs) have similar immune profiles in tertiary lymphoid structures of lung cancer and non-TLS areas, with tumor-infiltrating Tregs found to inhibit the proliferation and cytokine secretion of CD4 + conventional T cells.
Externí odkaz:
https://doaj.org/article/6843b8158e4442199fa24d4eee02cf0d
Autor:
Marco Alifano, Elisa Daffré, Laurent Brouchet, Pierre Emmanuel Falcoz, Françoise Le Pimpec Barthes, Pierre Benoit Pages, Pascal Alexandre Thomas, Marcel Dahan, Raphael Porcher
Publikováno v:
The Lancet Regional Health. Europe, Vol 26, Iss , Pp 100566- (2023)
Summary: Background: Prognostic assessment in patients undergoing cancer treatments is of paramount importance to plan subsequent management. In resectable lung cancer availability of an easy-to use nomogram to predict long-term outcome would be extr
Externí odkaz:
https://doaj.org/article/0ed14c2afb89459384b3997f3d033530
Autor:
Olivier Schussler, Luc Maroteaux, Ramadan Jashari, Pierre Falcoz, Marco Alifano, Yves Lecarpentier, Jean-Marie Launay
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectivesAlthough critical in animal and human development and pathology, a measurement of the quantitative expression of 5-HTR serotonin receptors on animal or human valvular tissues has never been performed.MethodsQuantification of the most freque
Externí odkaz:
https://doaj.org/article/0bb0bc890b344042b7fd358211a161ae
Autor:
Diane Damotte, Sarah Warren, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Audrey Mansuet-Lupo, Jérôme Biton, Hanane Ouakrim, Marco Alifano, Claire Gervais, Audrey Bellesoeur, Nora Kramkimel, Camille Tlemsani, Barbara Burroni, Angéline Duche, Franck Letourneur, Han Si, Rebecca Halpin, Todd Creasy, Ronald Herbst, Xing Ren, Pascale Morel, Alessandra Cesano, François Goldwasser, Karen Leroy
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The 18-gene tumor inflammation signature (TIS) is a clinical research assay that enriches for clinical benefit to immune checkpoint blockade. We evaluated its ability to predict clinical benefit of immunotherapy in cancer patients
Externí odkaz:
https://doaj.org/article/b75c5fd83d2d4639a48bed140c36dd2f