Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Marcio O. Lasaro"'
Autor:
Natalie A Hutnick, Diane G Carnathan, Sheri A Dubey, Kara S Cox, Lisa Kierstead, George Makadonas, Sarah J Ratcliffe, Marcio O Lasaro, Michael N Robertson, Danilo R Casimiro, Hildegund C J Ertl, Michael R Betts
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14385 (2010)
Adenoviral (Ad) vaccine vectors represent both a vehicle to present a novel antigen to the immune system as well as restimulation of immune responses against the Ad vector itself. To what degree Ad-specific CD8(+) T cells are restimulated by Ad vecto
Externí odkaz:
https://doaj.org/article/cedc147c5422474d948e752b10f259e7
Autor:
Maria Myzithras, Erica Waltz, Irina Rybina, Zhong-Fu Huang, Jennifer Ahlberg, Tammy Bigwarfe, Haiguang Xiao, Rachel Kroe-Barrett, Marcio O. Lasaro, Himanshu Saraf, Simon Roberts, Cynthia Hess Kenny, Danlin Yang, Steven Castellano, Sanjaya Singh, Craig Giragossian
Publikováno v:
mAbs
Antibodies with pH-dependent binding to both target antigens and neonatal Fc receptor (FcRn) provide an alternative tool to conventional neutralizing antibodies, particularly for therapies where reduction in antigen level is challenging due to high t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53eac44c654c862fa41923786e5554e5
https://doi.org/10.1080/19420862.2017.1359455
https://doi.org/10.1080/19420862.2017.1359455
Autor:
Danlin Yang, Lee Frego, Sanjaya Singh, Rachel Kroe-Barrett, Kristopher Truncali, Marcio O. Lasaro
Publikováno v:
Journal of Biological Chemistry
The Journal of Biological Chemistry
The Journal of Biological Chemistry
To determine the effectiveness of immunization strategies used in therapeutic antibody or vaccine development, it is critical to assess the quality of immunization-induced polyclonal antibody responses. Here, we developed a workflow that uses sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167408d435f2d386d0120ddaf7ac7530
Autor:
Sócrates Herrera, Ariane Guglielmi Ariza Camacho, Marcio O. Lasaro, Monica T. Leal, Jonatan Ersching, Ruth S. Nussenzweig, Victor Nussenzweig, Irene S. Soares, Cibele Aparecida Tararam, Hildegund C.J. Ertl, Mauricio M. Rodrigues, Oscar Bruna-Romero, Laís Helena Teixeira
Publikováno v:
Infection and Immunity. 82:793-807
Plasmodium vivax is the most widespread and the second most prevalent malaria-causing species in the world. Current measures used to control the transmission of this disease would benefit from the development of an efficacious vaccine. In the case of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbed646013805df64f38e77bf28cfe9
https://doi.org/10.1128/iai.01410-13
https://doi.org/10.1128/iai.01410-13
Autor:
Ivo C. Lorenz, Marcio O. Lasaro, Habtom H. Habte, William M. Gelbart, Martina Sykora, Adam Biddlecome, Charles M. Knobler, Knut Elbers, Katherine M. McGrath, Melanie Wurm, Sharmila Sambanthamoorthy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 6, p e0215031 (2019)
PLoS ONE, Vol 14, Iss 6, p e0215031 (2019)
Many mRNA-based vaccines have been investigated for their specific potential to activate dendritic cells (DCs), the highly-specialized antigen-presenting cells of the immune system that play a key role in inducing effective CD4+ and CD8+ T-cell respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da9ececa74bef15345fb9008e99747c
https://doi.org/10.1371/journal.pone.0215031
https://doi.org/10.1371/journal.pone.0215031
Autor:
B. Manson, Marcio O. Lasaro, E. J. Wherry, Juliana C. Small, S. Kannan, Hildegund C. J. Ertl, L. J. DiMenna, E. M. Parzych, B. P. Latimer
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2013 (2013)
BioMed Research International, Vol 2013 (2013)
Influenza viruses cause severe illnesses and death, mainly in the aged population. Protection afforded by licensed vaccines through subtype-specific neutralizing antibodies is incomplete, especially when the vaccine antigens fail to closely match tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0020d7156957d59b356803a8ab77b4be
https://doi.org/10.1155/2013/876314
https://doi.org/10.1155/2013/876314
Autor:
Ang Bian, David A. Garber, Lauren J. DiMenna, Yan Li, Mark G. Lewis, Zhiquan Xiang, Wynetta Giles-Davis, Hildegund C. J. Ertl, Michael R. Betts, Marina Sazanovich, Nicole R. Klatt, Hua Li, Sarah J. Ratcliffe, Marcio O. Lasaro, Juliana C. Small, Xiangyang Zhou, Raj K. Kurupati, R.M. Leskowitz, Elizabeth Parzych, Jessica C. Engram, Jason M. Brenchley, Larissa H. Haut, Dongming Zhou, Guido Silvestri, Te Lang Wu
Publikováno v:
Molecular Therapy. 19(2):417-426
Despite enormous efforts by the scientific community, an effective HIV vaccine remains elusive. To further address to what degree T cells in absence of antibodies may protect against simian immunodeficiency virus (SIV) disease progression, rhesus mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3986bc59417326eeaebb7776f4a380b
Autor:
Marcio O. Lasaro, Jan Erikson, Hua Li, Brian P Latimer, Dongming Zhou, Yan Li, Te-Lang Wu, Hildegund C.J. Ertl, Zhiquan Xiang, Elizabeth Parzych, Ang Bian
Publikováno v:
Molecular Therapy. 18:2182-2188
A universal influenza vaccine, designed to induce broadly cross-reactive immunity against current and future influenza A virus strains, is in critical demand to reduce the need for annual vaccinations with vaccines chosen upon predicting the predomin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f489ed9213ae62f6f5b1581316fec
https://doi.org/10.1038/mt.2010.202
https://doi.org/10.1038/mt.2010.202
Autor:
Marcio O. Lasaro, Wynetta Giles-Davis, Lauren J. DiMenna, Elizabeth Parzych, Larissa H. Haut, Brian Manson, Hong Yu, Hildegund C. J. Ertl, Sarah Abdulla, Katrin Töpfer, Brian P Latimer, Dongming Zhou
Publikováno v:
The Journal of Immunology. 184:5475-5484
Immune responses diminish with age resulting in an increased susceptibility of the elderly to infectious agents and an inability to mount protective immune responses to vaccines. Immunosenescence affects multiple aspects of the immune system, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821c37f0a6ba8dfcd94c24ec294f0f31
https://doi.org/10.4049/jimmunol.0903808
https://doi.org/10.4049/jimmunol.0903808
Autor:
Hildegund C.J. Ertl, Marcio O. Lasaro
Publikováno v:
Molecular Therapy. 17(8):1333-1339
Adenovirus (Ad) vectors were initially developed for treatment of genetic diseases. Their usefulness for permanent gene replacement was limited by their high immunogenicity, which resulted in rapid elimination of transduced cells through induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d1bb6bf24a337913a209cb8d932028