Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marcio L.L. Martinez"'
Autor:
Ana C. Palei, Tatiane C. Izidoro-Toledo, Anna L.B. Jacob-Ferreira, Stefany Bruno de Assis Cau, Jose E. Tanus-Santos, Raquel F. Gerlach, Heitor Moreno, Marcio L.L. Martinez
Publikováno v:
European Journal of Pharmacology. 627:216-222
Nicotine plays a role in smoking-associated cardiovascular diseases, and may upregulate matrix metalloproteinase (MMP)-2 and MMP-9. We examined whether nicotine induces the release of MMP-2 and MMP-9 by rat smooth muscle cells (SMC), and whether doxy
Autor:
Raquel F. Gerlach, Jose E. Tanus-Santos, Lusiane M. Bendhack, Elen Rizzi, Caroline Demacq, Karla Fernandes, Marcio L.L. Martinez, Michele M. Castro
Publikováno v:
European Journal of Pharmacology. 591:224-230
Increased expression/activity of matrix metalloproteinases (MMPs), especially MMP-2, plays a role in the vascular alterations induced by hypertension, and increased oxidative stress is a major factor activating MMPs. Here, we hypothesized that lercan
Autor:
Fernando Nobre, Marcio L.L. Martinez, Lívia F. Lopes, Jose E. Tanus-Santos, João Rocha, Eduardo Barbosa Coelho, Raquel F. Gerlach
Publikováno v:
Journal of Cardiovascular Pharmacology. 47:117-122
Increased levels of metalloproteinase (MMP)-9 have been shown in hypertensive patients. Lercanidipine is a calcium channel blocker with antioxidant actions. We examined whether lercanidipine produces antioxidant effects and reduces MMP-9 activity in
Autor:
Michele M. Castro, Marcio L.L. Martinez, Raquel F. Gerlach, Jose E. Tanus-Santos, Karla Fernandes, Lusiane M. Bendhack, Elen Rizzi
Publikováno v:
European journal of pharmacology. 599(1-3)
Abnormal matrix metalloproteinases (MMPs) activity causes cardiovascular diseases. Because hyperglycemia increase MMPs activities through increased oxidative stress, we hypothesized that antioxidant effects produced by lercanidipine could attenuate t
Publikováno v:
The FASEB Journal. 22