Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marcin Sysa"'
Publikováno v:
Molecules, Vol 29, Iss 18, p 4301 (2024)
Ampicillin (AMP) and amoxicillin (AMX) are popular antibiotics, which are penicillin derivatives, and are used in both human and veterinary medicine. In the conducted study, AMP, AMX and their mixtures did not cause major changes in the total bacteri
Externí odkaz:
https://doaj.org/article/eee933ed92f4400dbefd80cce8639e8f
Autor:
Magdalena Izdebska, Mariola Herbet, Monika Gawrońska-Grzywacz, Iwona Piątkowska-Chmiel, Agnieszka Korga, Marcin Sysa, Magdalena Iwan, Dorota Natorska-Chomicka, Ewa Poleszak, Andrzej Wróbel, Sławomir Mandziuk, Jarosław Dudka
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
Purpose: The aim of this study was to evaluate the effect of resveratrol on de novo lipogenesis in HepG2 cells caused by high glucose concentrations. Increased lipogenesis in the liver is the main reason for the development of nonalcoholic fatty live
Externí odkaz:
https://doaj.org/article/54b313a3eb6240e0baa79e944fcf79aa
Autor:
Marcin Sysa, Magdalena Iwan, Marzena Rzadkowska, Dariusz Matosiuk, Ewelina Humeniuk, Agnieszka Korga, Jarosław Dudka, Elżbieta Szacoń, Marta Ostrowska
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 33, Iss 1, Pp 1-5 (2020)
Doxorubicin cardiotoxicity is caused by various mechanisms, most importantly by oxidative stress originating in the mitochondria. Tirapazamine is a hypoxia-activated anticancer experimental drug. Both drugs in normoxia conditions undergo univalent re
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 32, Iss 1, Pp 18-22 (2019)
Hypoxic cancer cells are more aggressive and responsible for more efficient metastasis and recurrence. It seems worth-while, hence, to supplement current cytostatic drugs therapy (i.e. cisplatin) with hypoxia cytotoxic agents (i.e. tirapazamine), the
Autor:
Marcin Sysa, Iwona Piątkowska-Chmiel, Monika Gawrońska-Grzywacz, Magdalena Izdebska, Mariola Herbet, Anna Biernasiuk, Łukasz Popiołek, Monika Wujec, Jarosław Dudka, Anna Malm
Publikováno v:
Biomedicine & Pharmacotherapy. 103:1337-1347
In this research we synthesized, identified and evaluated new hydrazide-hydrazones (1-3) and 1,3-thiazolidin-4-one derivatives (4-6) for in vitro and in vivo activity. New hydrazide-hydrazones (1-3) were obtained by the condensation reaction of 3-hyd
Autor:
Milena Soroka, Karolina Wicha, Ewelina Humeniuk, Marcin Sysa, Agnieszka Korga, Magdalena Iwan, Jarosław Dudka, Grzegorz Adamczuk
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 31, Iss 1, Pp 18-21 (2018)
One of the less known mechanisms of doxorubicin action is the effect on the functioning of the ubiquitin-proteasome degradation system (UPS). So far, the role of impaired proteasome activity in the development of anthracycline cardiomyopathy has not
The beneficial effects of resveratrol on steatosis and mitochondrial oxidative stress in HepG2 cells
Autor:
Monika Gawrońska-Grzywacz, Iwona Piątkowska-Chmiel, Magdalena Izdebska, Mariola Herbet, Marcin Sysa, Renata Gieroba, Agnieszka Korga, Klaudia Czajkowska-Bania, Marcelina Cygal, Agnieszka Korolczuk, Jarosław Dudka
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 95:1442-1453
Nonalcoholic fatty liver disease (NAFLD) is currently one of the most common chronic liver diseases, especially in developed countries. One group of substances with a potential use in the treatment of NAFLD are plant polyphenols, represented by resve
Autor:
Mariola Herbet, Dorota Natorska‑Chomicka, Agnieszka Korga, Jarosław Dudka, Iwona Piątkowska‑Chmiel, Monika Gawrońska‑Grzywacz, Marcin Sysa, Magdalena Iwan
Publikováno v:
Oncology reports. 43(3)
Kidney cancer is one of the most lethal urological malignancies associated with a high risk of mortality. Recent studies have shown that several antidiabetic drugs may limit the risk of the growth of different types of cancer. Pioglitazone (PIO) belo
Autor:
Agnieszka Korga, Dorota Natorska-Chomicka, Ewa Poleszak, Monika Gawrońska-Grzywacz, Jarosław Dudka, Mariola Herbet, Slawomir Mandziuk, Iwona Piątkowska-Chmiel, Marcin Sysa, Andrzej Wróbel, Magdalena Iwan, Magdalena Izdebska
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
Purpose: The aim of this study was to evaluate the effect of resveratrol on de novo lipogenesis in HepG2 cells caused by high glucose concentrations. Increased lipogenesis in the liver is the main reason for the development of nonalcoholic fatty live
Autor:
Iwona Piątkowska-Chmiel, Mariola Herbet, Brygida Ślaska, Jarosław Dudka, Monika Gawrońska-Grzywacz, Kamil Pawłowski, Dorota Natorska-Chomicka, Magdalena Izdebska, Marcin Sysa
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2018 (2018)
BioMed Research International, Vol 2018 (2018)
Chronic exposure to stress factors contributes to the development of depression by generating excess of reactive oxygen species which leads to oxidative stress and inflammatory processes. The aim of the study was to assess the potential protective pr