Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marcin Nicos"'
Autor:
Luuk Harbers, Federico Agostini, Marcin Nicos, Dimitri Poddighe, Magda Bienko, Nicola Crosetto
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Somatic copy number alterations (SCNAs) are a pervasive trait of human cancers that contributes to tumorigenesis by affecting the dosage of multiple genes at the same time. In the past decade, The Cancer Genome Atlas (TCGA) and the International Canc
Externí odkaz:
https://doaj.org/article/ebd2ea5dc4434345b6f133692597633a
Autor:
Marcin Nicos, Luuk Harbers, Enrico Patrucco, Maximilian Kramer-Drauberg, Xiaolu Zhang, Claudia Voena, Anna Kowalczyk, Aleksandra Bozyk, Rafal Peksa, Bozena Jarosz, Justyna Szumilo, Michele Simonetti, Monika Zuk, Bartosz Wasag, Katarzyna Reszka, Renata Duchnowska, Janusz Milanowski, Roberto Chiarle, Magda Bienko, Pawel Krawczyk, Jacek Jassem, Chiara Ambrogio, Nicola Crosetto
Brain metastases (BM) severely impact the prognosis and quality of life of patients with non-small cell lung cancer (NSCLC). To identify targetable drivers of NSCLC-BM, we profiled somatic copy number alterations (SCNAs) in 51 matched pairs of primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c93344cf030b053dcee213568a2801f
https://doi.org/10.21203/rs.3.rs-1320380/v1
https://doi.org/10.21203/rs.3.rs-1320380/v1
Autor:
Alicja Rączkowska, Iwona Paśnik, Michał Kukiełka, Marcin Nicoś, Magdalena A. Budzinska, Tomasz Kucharczyk, Justyna Szumiło, Paweł Krawczyk, Nicola Crosetto, Ewa Szczurek
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract Background Despite the fact that tumor microenvironment (TME) and gene mutations are the main determinants of progression of the deadliest cancer in the world – lung cancer, their interrelations are not well understood. Digital pathology d
Externí odkaz:
https://doaj.org/article/b9d927256bad4ba687e5a6bb6f27c878
Autor:
Marcin Nicoś, PhD, Luuk Harbers, MSc, Enrico Patrucco, PhD, Maximilian Kramer-Drauberg, PhD, Xiaolu Zhang, PhD, Claudia Voena, PhD, Anna Kowalczyk, MD, PhD, Aleksandra Bożyk, PhD, Rafał Pęksa, MD, PhD, Bożena Jarosz, MD, PhD, Justyna Szumiło, MD, Michele Simonetti, PhD, Monika Żuk, PhD, Bartosz Wasąg, MD, Katarzyna Reszka, PhD, Renata Duchnowska, MD, Janusz Milanowski, MD, Roberto Chiarle, MD, Magda Bienko, PhD, Paweł Krawczyk, MD, Jacek Jassem, MD, Chiara Ambrogio, PhD, Nicola Crosetto, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 12, Pp 100435- (2022)
Introduction: Brain metastases (BM) severely affect the prognosis and quality of life of patients with NSCLC. Recently, molecularly targeted agents were found to have promising activity against BM in patients with NSCLC whose primary tumors carry “
Externí odkaz:
https://doaj.org/article/93978b32039848998a35af7844ee33cf
Autor:
Anna Grenda, Justyna Błach, Michał Szczyrek, Paweł Krawczyk, Marcin Nicoś, Barbara Kuźnar Kamińska, Monika Jakimiec, Grażyna Balicka, Izabela Chmielewska, Halina Batura‐Gabryel, Marek Sawicki, Janusz Milanowski
Publikováno v:
Cancer Medicine, Vol 9, Iss 2, Pp 605-614 (2020)
Abstract Background Topoisomerase 2‐alpha (TOP2A) is an enzyme that controls topologic changes in DNA during transcription and replication. ERCC1 is an enzyme that takes part in DNA repair processes. The purpose of this study was to assess the pred
Externí odkaz:
https://doaj.org/article/58770bce40d5492099a86eba3484740c
Autor:
Aleksandra Bożyk, Marcin Nicoś
Publikováno v:
Life, Vol 12, Iss 10, p 1640 (2022)
The standard diagnostics procedure for non-small-cell lung cancer (NSCLC) requires a pathological evaluation of tissue samples obtained by surgery or biopsy, which are considered invasive sampling procedures. Due to this fact, re-sampling of the prim
Externí odkaz:
https://doaj.org/article/217129180e4d43b18092cecdc26d8b67
Autor:
Xiaolu Zhang, Silvano Garnerone, Michele Simonetti, Luuk Harbers, Marcin Nicoś, Reza Mirzazadeh, Tiziana Venesio, Anna Sapino, Johan Hartman, Caterina Marchiò, Magda Bienko, Nicola Crosetto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Genomics DNA library preparation from formalin-fixed paraffin-embedded tissues is challenging. Here the authors describe CUTseq that uses restriction enzymes and in vitro amplification to barcode samples for reduced representation genome sequencing.
Externí odkaz:
https://doaj.org/article/5bd13737717a4dc7914df1406868bf3e
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Immune checkpoint inhibitors (ICIs) represent one of the most promising therapeutic approaches in metastatic non-small cell lung cancer (M-NSCLC). Unfortunately, approximately 50–75% of patients do not respond to this treatment modality. Intratumor
Externí odkaz:
https://doaj.org/article/be6f9a2104e44a109275a6e9c005dfc7
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The use of immune checkpoint inhibitors (ICIs) delivered great and new possibilities in modern treatment of many types of cancers. This therapy based on blockade of such molecules as CTLA-4 (cytotoxic T lymphocyte-associated antigen), PD-1 (programme
Externí odkaz:
https://doaj.org/article/4f4650e0663842eebd28bb038b17d5de
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0138b03f9aa0f591f73b70ae8fc5dae7
http://www.scopus.com/inward/record.url?eid=2-s2.0-85013828861&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-85013828861&partnerID=MN8TOARS