Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marcin Mielecki"'
Autor:
Marcin Mielecki, Marcin Ziemniak, Magdalena Ozga, Radosław Borowski, Jarosław Antosik, Angelika Kaczyńska, Beata Pająk
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1111 (2022)
Protein aggregation is a well-recognized problem in industrial preparation, including biotherapeutics. These low-energy states constantly compete with a native-like conformation, which is more pronounced in the case of macromolecules of low stability
Externí odkaz:
https://doaj.org/article/16e5a8f46d36429daa0f92672fe79a37
Autor:
Damian Mielecki, Dorota Ł Zugaj, Anna Muszewska, Jan Piwowarski, Aleksandra Chojnacka, Marcin Mielecki, Jadwiga Nieminuszczy, Marcin Grynberg, Elżbieta Grzesiuk
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30588 (2012)
BackgroundALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly
Externí odkaz:
https://doaj.org/article/e753042fc77542ea8e75a36a18874a4c
Autor:
Magdalena Chojnacka, Wiesław Bielawski, Beata Prabucka, Marcin Mielecki, Mariusz Czarnocki-Cieciura, Sławomir Orzechowski
Publikováno v:
Phytochemistry. 142:1-10
Phytocystatins are a group of proteins with significant potential to regulate activities of cysteine proteinases of native and pest/pathogen origins. The two-domain triticale (x Triticosecale Wittm.) phytocystatin TrcC-8 was characterized in this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849bfd86730d8363118d719fca7301e6
https://doi.org/10.1016/j.phytochem.2017.06.008
https://doi.org/10.1016/j.phytochem.2017.06.008
Autor:
Peter Verwilst, Justyn Wojtasik, Wim Dehaen, Katarzyna Kurzątkowska, Krystyna Grzelak, Jerzy Radecki, Hanna Radecka, Marcin Mielecki
Publikováno v:
Sensors and Actuators B: Chemical. 196:223-230
Here, the new biosensor destined for screening of interactions between kinase JAK2 and compounds which may act as inhibitors was presented. The Cu(II) complex of pentetic acid thiol ligand was applied for immobilization of kinase JAK2 on the gold ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88b449a209e79132d528b4e642e2d9c3
https://doi.org/10.1016/j.snb.2014.01.095
https://doi.org/10.1016/j.snb.2014.01.095
Autor:
Piotr Świerk, Slawomir Szymanski, Marcin Mielecki, Kamila Kowa, Włodzimierz Zagórski, Irene Kiburu, Wiesław Szeja, Krystyna Grzelak, Bogdan Lesyng, Borys Kierdaszuk, Krzysztof Krawiec, Nicole LaRonde-LeBlanc, Waldemar Priebe, Izabela Fokt
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1834:1292-1301
The RIO kinases are essential protein factors required for the synthesis of new ribosomes in eukaryotes. Conserved in archaeal organisms as well, RIO kinases are among the most ancient of protein kinases. Their exact molecular mechanisms are under in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68998a60e910e7c37d3aa64a16f3c178
https://doi.org/10.1016/j.bbapap.2013.03.012
https://doi.org/10.1016/j.bbapap.2013.03.012
Autor:
Katarzyna Kurzątkowska, Jerzy Radecki, Wim Dehaen, Justyn Wojtasik, Magdalena Zborowska, Hanna Radecka, Marcin Mielecki, Krystyna Grzelak
Publikováno v:
Electrochimica Acta. 96:147-154
The fabrication of electrochemical biosensor consists of the following successive steps: formation of thiol derivative of iminodiacetic acid (IDA-like/N-heterocyclic donor) and N -acetylcysteamine (NAC) self-assembled monolayer on the Au electrode, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fb51683acf8e604348ffc425998fbf
https://doi.org/10.1016/j.electacta.2013.02.085
https://doi.org/10.1016/j.electacta.2013.02.085
Autor:
Marcin Mielecki, Bogdan Lesyng
Publikováno v:
Current medicinal chemistry. 23(10)
Cinnamic acid belongs to phenolic-acid class of polyphenols, one of the most abundant plant secondary metabolites. These substances are widely studied because of plethora of their biological activities. In particular, their inhibition of protein kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10b787407e042b92d7a4aecea5f5750
https://pubmed.ncbi.nlm.nih.gov/26980568
https://pubmed.ncbi.nlm.nih.gov/26980568
Autor:
Ryozo Imai, Magdalena Chojnacka, Joanna Szewińska, Marcin Mielecki, Sławomir Orzechowski, Wiesław Bielawski, Małgorzata Nykiel
Publikováno v:
Journal of plant physiology. 174
Water-deficit is accompanied by an increase in proteolysis. Phytocystatins are plant inhibitors of cysteine proteinases that belong to the papain and legumain family. A cDNA encoding the protein inhibitor TrcC-8 was identified in the vegetative organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d241c95cd4d82c63b17e621b2cc84d
https://pubmed.ncbi.nlm.nih.gov/25462979
https://pubmed.ncbi.nlm.nih.gov/25462979
Autor:
Hanna Radecka, Jerzy Radecki, Katarzyna Kurzątkowska, Krystyna Grzelak, Peter Verwilst, Wim Dehaen, Marcin Mielecki
Publikováno v:
Talanta. 130
New surface plasmon resonance (SPR) sensing platforms which consists of copper (II) complexes of a pentetic acid thiol ligand (DPTA-Cu(II)) and of a thiol derivative of dipyrromethene (DPM-Cu(II) created on the surface of gold SPR disc were applied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2715d9e0188d4e006b7535d9b7aad0a0
https://pubmed.ncbi.nlm.nih.gov/25159418
https://pubmed.ncbi.nlm.nih.gov/25159418
Autor:
Anna Muszewska, Dorota Łucja Zugaj, Marcin Grynberg, Elżbieta Grzesiuk, Aleksandra Chojnacka, Damian Mielecki, Jadwiga Nieminuszczy, Jan Piwowarski, Marcin Mielecki
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 1, p e30588 (2012)
PLoS ONE, Vol 7, Iss 1, p e30588 (2012)
BackgroundALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdabdc26d7974df5ae7a3224776f7cec
http://europepmc.org/articles/PMC3265494
http://europepmc.org/articles/PMC3265494