Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Marcin Kwissa"'
Autor:
Lisa R. Volpatti, Rachel P. Wallace, Shijie Cao, Michal M. Raczy, Ruyi Wang, Laura T. Gray, Aaron T. Alpar, Priscilla S. Briquez, Nikolaos Mitrousis, Tiffany M. Marchell, Maria Stella Sasso, Mindy Nguyen, Aslan Mansurov, Erica Budina, Ani Solanki, Elyse A. Watkins, Mathew R. Schnorenberg, Andrew C. Tremain, Joseph W. Reda, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Shann S. Yu, Balaji Manicassamy, James L. LaBelle, Matthew V. Tirrell, Glenn Randall, Marcin Kwissa, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
Externí odkaz:
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Objective and design BacSp222 bacteriocin is a bactericidal and proinflammatory peptide stimulating immune cells to produce selected cytokines and NO in NF-ĸB dependent manner. This study aims to identify the receptor which mediates this activity. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9339fb8bdfcb1d9d50e87642c142c0
https://doi.org/10.21203/rs.3.rs-2581983/v1
https://doi.org/10.21203/rs.3.rs-2581983/v1
Autor:
Laura T. Gray, Glenn Randall, Mindy Nguyen, Matthew Tirrell, Marcin Kwissa, Steve Dvorkin, Aaron T. Alpar, Balaji Manicassamy, Jeffrey A. Hubbell, Nikolaos Mitrousis, Elyse A. Watkins, James L. LaBelle, Tiffany M. Marchell, Erica Budina, Shann S. Yu, Shijie Cao, Ruyi Wang, Rachel P. Wallace, Michal M. Raczy, Mathew R. Schnorenberg, Kevin Furlong, Vlad Nicolaescu, Lisa R. Volpatti, Andrew C Tremain, Melody A. Swartz, Joseph W. Reda, Aslan Mansurov, Maria Stella Sasso, Priscilla S. Briquez, Ani Solanki
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
The COVID-19 pandemic underscores the need for rapid, safe, and effective vaccines. In contrast to some traditional vaccines, nanoparticle-based subunit vaccines are particularly efficient in trafficking antigens to lymph nodes, where they induce pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eb21cfa353bc8b2d6928782bffd622
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Autor:
Jean-François Franetich, Sachiko Hirosue, Maria A. S. Broggi, Giacomo Diaceri, Melody A. Swartz, Xavier Quaglia-Thermes, Marcin Kwissa, Jeffrey A. Hubbell, Dominique Mazier, Leonardo Bonilla-Ramirez, Laura Jeanbart, D. Scott Wilson, Ruyi Wang, Michal M. Raczy
Publikováno v:
Nature Materials. 18:175-185
Fully effective vaccines for complex infections must elicit a diverse repertoire of antibodies (humoral immunity) and CD8+ T-cell responses (cellular immunity). Here, we present a synthetic glyco-adjuvant named p(Man–TLR7), which, when conjugated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee076d94a592abcf84502db63df7467
https://doi.org/10.1038/s41563-018-0256-5
https://doi.org/10.1038/s41563-018-0256-5
Autor:
Tiffany M. Marchell, Nikolaos Mitrousis, Ruyi Wang, Laura T. Gray, Glenn Randall, Melody A. Swartz, Marcin Kwissa, Rachel P. Wallace, Kevin Furlong, Vlad Nicolaescu, Michal M. Raczy, Mindy Nguyen, Elyse A. Watkins, Balaji Manicassamy, Andrew C Tremain, D. Scott Wilson, Lisa R. Volpatti, Ani Solanki, Steve Dvorkin, Maria Stella Sasso, Shijie Cao, Erica Budina, Aaron T. Alpar, Jeffrey A. Hubbell, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Shann S. Yu
The SARS-CoV-2 virus has caused an unprecedented global crisis, and curtailing its spread requires an effective vaccine which elicits a diverse and robust immune response. We have previously shown that vaccines made of a polymeric glyco-adjuvant conj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::609dc88b5ac6a29a8652cb34dab4d818
https://doi.org/10.1101/2021.05.20.445060
https://doi.org/10.1101/2021.05.20.445060
Autor:
Ani Solanki, Marcin Kwissa, Andrew C Tremain, Vlad Nicolaescu, Aaron T. Alpar, Nikolaos Mitrousis, Melody A. Swartz, Lisa R. Volpatti, Shann S. Yu, Rachel P. Wallace, Matthew Tirrell, Ruyi Wang, Elyse A. Watkins, Maria Stella Sasso, Tiffany M. Marchell, Balaji Manicassamy, Michal M. Raczy, Shijie Cao, Steve Dvorkin, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Kevin Furlong, Mathew R. Schnorenberg, Glenn Randall, Erica Budina, Mindy Nguyen, Laura T. Gray, Jeffrey A. Hubbell, James L. LaBelle
A diverse portfolio of SARS-CoV-2 vaccine candidates is needed to combat the evolving COVID-19 pandemic. Here, we developed a subunit nanovaccine by conjugating SARS-CoV-2 Spike protein receptor binding domain (RBD) to the surface of oxidation-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29e4a1f213b1a04920be54ae8e85047
https://doi.org/10.1101/2021.04.08.438884
https://doi.org/10.1101/2021.04.08.438884
Autor:
Ruyi Wang, Nikolaos Mitrousis, Melody A. Swartz, Kevin Furlong, D. Scott Wilson, Vlad Nicolaescu, Elyse A. Watkins, Tiffany M. Marchell, Lisa R. Volpatti, Balaji Manicassamy, Andrew C Tremain, Glenn Randall, Rachel P. Wallace, Ani Solanki, Laura T. Gray, Steve Dvorkin, Marcin Kwissa, Maria Stella Sasso, Mindy Nguyen, Aaron T. Alpar, Michal M. Raczy, Jeffrey A. Hubbell, Erica Budina, Shijie Cao, Shann S. Yu, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez
Publikováno v:
Biomaterials
The SARS-CoV-2 virus has caused an unprecedented global crisis, and curtailing its spread requires an effective vaccine which elicits a diverse and robust immune response. We have previously shown that vaccines made of a polymeric glyco-adjuvant conj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b93d0c83332f519748f85280205edd
http://europepmc.org/articles/PMC8482845
http://europepmc.org/articles/PMC8482845
Publikováno v:
Blood. 119:2044-2055
TLR ligands (TLR-Ls) represent novel vaccine adjuvants, but their immunologic effects in humans remain poorly defined in vivo. In the present study, we analyzed the innate responses stimulated by different TLR-Ls in rhesus macaques. MPL (TLR4-L), R-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa4c3fc747f945ca59061230b17e60d
https://doi.org/10.1182/blood-2011-10-388579
https://doi.org/10.1182/blood-2011-10-388579
Autor:
Tang Hua, Joshy Jacob, Niren Murthy, Adolfo García-Sastre, Robert J. Hogan, Sudhir Pai Kasturi, Ioanna Skountzou, Bali Pulendran, Rajesh Ravindran, Dimitrios G. Koutsonanos, Randy A. Albrecht, Munir Alam, Richard W. Compans, Marcin Kwissa, Francois Villinger, Shelley Stewart, John Steel, Helder I. Nakaya
Publikováno v:
Nature. 470:543-547
A feature of many successful vaccines is the induction of memory B cells and long-lived plasma cells that can secrete neutralizing antibodies for a lifetime. The mechanisms that stimulate such persistent responses remain poorly understood. Bali Pulen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4cb6d541a837abcc9408bfff3874b0
https://doi.org/10.1038/nature09737
https://doi.org/10.1038/nature09737
Autor:
Harriet L. Robinson, Marcin Kwissa, Rama Rao Amara, Sefik S. Alkan, Abdul Jabbar, Bali Pulendran, Bernard Moss, Francois Villinger
Publikováno v:
The Journal of Experimental Medicine
DNA vaccines offer promising strategies for immunization against infections. However, their clinical use requires improvements in immunogenicity. We explored the efficacy of Toll-like receptor (TLR) ligands (TLR-Ls) on augmenting the immunogenicity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba56bd962813e19090ea3c4b27b19042
https://doi.org/10.1084/jem.20071211
https://doi.org/10.1084/jem.20071211