Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Marcin Kierczak"'
Autor:
Verena E. Kutschera, Marcin Kierczak, Tom van der Valk, Johanna von Seth, Nicolas Dussex, Edana Lord, Marianne Dehasque, David W. G. Stanton, Payam Emami Khoonsari, Björn Nystedt, Love Dalén, David Díez-del-Molino
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Many wild species have suffered drastic population size declines over the past centuries, which have led to ‘genomic erosion’ processes characterized by reduced genetic diversity, increased inbreeding, and accumulation of harm
Externí odkaz:
https://doaj.org/article/cd40e0643311421e8edf12c3f8400a40
Autor:
Marcin Kierczak, Nima Rafati, Julia Höglund, Hadrien Gourlé, Valeria Lo Faro, Daniel Schmitz, Weronica E. Ek, Ulf Gyllensten, Stefan Enroth, Diana Ekman, Björn Nystedt, Torgny Karlsson, Åsa Johansson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Despite the success of genome-wide association studies, much of the genetic contribution to complex traits remains unexplained. Here, the authors identify effects by rare variants on plasma proteins, and estimate the contribution of rare variants to
Externí odkaz:
https://doaj.org/article/1070fe1cf0884dc9a1fe9d7ebf5b6af9
Autor:
Frode Lingaas, Katarina Tengvall, Johan Høgset Jansen, Lena Pelander, Maria H Hurst, Theo Meuwissen, Åsa Karlsson, Jennifer R S Meadows, Elisabeth Sundström, Stein Istre Thoresen, Ellen Frøysadal Arnet, Ole Albert Guttersrud, Marcin Kierczak, Marjo K Hytönen, Hannes Lohi, Åke Hedhammar, Kerstin Lindblad-Toh, Chao Wang
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010599 (2023)
Chronic kidney disease (CKD) affects 10% of the human population, with only a small fraction genetically defined. CKD is also common in dogs and has been diagnosed in nearly all breeds, but its genetic basis remains unclear. Here, we performed a Baye
Externí odkaz:
https://doaj.org/article/c3c378efd65a49dc8c7bb3289499d511
Autor:
Maja Arendt, Aime Ambrosen, Tove Fall, Marcin Kierczak, Katarina Tengvall, Jennifer R. S. Meadows, Åsa Karlsson, Anne-Sofie Lagerstedt, Tomas Bergström, Göran Andersson, Kerstin Lindblad-Toh, Ragnvi Hagman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Pyometra is one of the most common diseases in female dogs, presenting as purulent inflammation and bacterial infection of the uterus. On average 20% of intact female dogs are affected before 10 years of age, a proportion that varies greatly
Externí odkaz:
https://doaj.org/article/467d05073fb149be93e6bcde4a0d7288
Autor:
Johanna von Seth, Nicolas Dussex, David Díez-del-Molino, Tom van der Valk, Verena E. Kutschera, Marcin Kierczak, Cynthia C. Steiner, Shanlin Liu, M. Thomas P. Gilbert, Mikkel-Holger S. Sinding, Stefan Prost, Katerina Guschanski, Senthilvel K. S. S. Nathan, Selina Brace, Yvonne L. Chan, Christopher W. Wheat, Pontus Skoglund, Oliver A. Ryder, Benoit Goossens, Anders Götherström, Love Dalén
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Highly endangered species like the Sumatran rhinoceros are at risk from inbreeding. Five historical and 16 modern genomes from across the species range show mutational load, but little evidence for local adaptation, suggesting that future inbreeding
Externí odkaz:
https://doaj.org/article/2ca4ea65799945a881d363596de220e7
Autor:
Thuy T. Luu, Jonas Nørskov Søndergaard, Lucía Peña-Pérez, Shabnam Kharazi, Aleksandra Krstic, Stephan Meinke, Laurent Schmied, Nicolai Frengen, Yaser Heshmati, Marcin Kierczak, Thibault Bouderlique, Arnika Kathleen Wagner, Charlotte Gustafsson, Benedict J. Chambers, Adnane Achour, Claudia Kutter, Petter Höglund, Robert Månsson, Nadir Kadri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells play roles in viral clearance and early surveillance against malignant transformation, yet our knowledge of the underlying mechanisms controlling their development and functions remain incomplete. To reveal cell fate-determi
Externí odkaz:
https://doaj.org/article/c1dc67fc499e4b4183fc91fffcbae0a1
Autor:
Lucía Peña-Pérez, Shabnam Kharazi, Nicolai Frengen, Aleksandra Krstic, Thibault Bouderlique, Julia Hauenstein, Minghui He, Ece Somuncular, Xiaoze Li Wang, Carin Dahlberg, Charlotte Gustafsson, Ann-Sofie Johansson, Julian Walfridsson, Nadir Kadri, Petter Woll, Marcin Kierczak, Hong Qian, Lisa Westerberg, Sidinh Luc, Robert Månsson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The development of B cells relies on an intricate network of transcription factors critical for developmental progression and lineage commitment. In the B cell developmental trajectory, a temporal switch from predominant Foxo3 to Foxo1 expression occ
Externí odkaz:
https://doaj.org/article/8607115034c64df893cbadd484c41780
Autor:
Ancuţa Cristina Raclariu-Manolică, Jarl Andreas Anmarkrud, Marcin Kierczak, Nima Rafati, Birgitte Lisbeth Graae Thorbek, Audun Schrøder-Nielsen, Hugo J. de Boer
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Herbs and spices are some of the most vulnerable products in terms of fraud and adulteration in the food sector. Although standard analytical methods are accurate for quality control of specific lead or marker compounds, they cannot accurately assess
Externí odkaz:
https://doaj.org/article/2814b8bb931b4c8fa95ed80cca8f171d
Autor:
Kerstin Lindblad-Toh, Voichita D. Marinescu, Karin Forsberg-Nilsson, Marcin Kierczak, Matthew Breen, Jaime F. Modiano, Jennifer R.S. Meadows, Gad Getz, Mats E. Pettersson, William C. Kisseberth, C. Guillermo Couto, Erik Axelsson, Jessica Alföldi, Steven E. Schumacher, Jeremy Johnson, Ross Swofford, Jason Turner-Maier, Rachael Thomas, Maja L. Arendt, Jaegil Kim, Ingegerd Elvers, Sharadha Sakthikumar
File contains list of GISTIC Defined Recurrent SCNA genes that overlap between Humans and Dogs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69028a3d98f30fad4fd8469b4af54a7b
https://doi.org/10.1158/0008-5472.22420380.v1
https://doi.org/10.1158/0008-5472.22420380.v1
Autor:
Kerstin Lindblad-Toh, Voichita D. Marinescu, Karin Forsberg-Nilsson, Marcin Kierczak, Matthew Breen, Jaime F. Modiano, Jennifer R.S. Meadows, Gad Getz, Mats E. Pettersson, William C. Kisseberth, C. Guillermo Couto, Erik Axelsson, Jessica Alföldi, Steven E. Schumacher, Jeremy Johnson, Ross Swofford, Jason Turner-Maier, Rachael Thomas, Maja L. Arendt, Jaegil Kim, Ingegerd Elvers, Sharadha Sakthikumar
Supplementary Figure 1 - Workflow for Somatic Point and Indel Mutation detection. Supplementary Figure 2 - Heatmap counts of samples with recurrent focal SCNAs per chromosome. Supplementary Figure 3 - oaCGH profiles penetrance plots and GISTIC analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c49dbd17269081d48a6b5022fb903b9
https://doi.org/10.1158/0008-5472.22420383
https://doi.org/10.1158/0008-5472.22420383