Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marcin J. Woźniak"'
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1695 (2024)
Acute kidney injury (AKI) affects 10–15% of hospitalised patients and arises after severe infections, major surgeries, or exposure to nephrotoxic drugs. AKI diagnosis based on creatinine level changes lacks specificity and may be delayed. MicroRNAs
Externí odkaz:
https://doaj.org/article/f51f9f1861ea4f95bd63a321be87df55
Autor:
Jemima Osekafore Adewuyi, Roshan Patel, Riccardo Abbasciano, Gerry P. McCann, Gavin Murphy, Marcin J. Woźniak, Anvesha Singh
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 1809-1817 (2022)
Abstract Aortic stenosis (AS) is the commonest valve lesion requiring surgery in the Western world. The presence of myocardial fibrosis is associated with mortality even after valve replacement. MicroRNAs could serve as biomarkers of fibrosis and ris
Externí odkaz:
https://doaj.org/article/fd458f6b3c864bc38b9836bee97bac4e
Urinary extracellular vesicles and micro-RNA as markers of acute kidney injury after cardiac surgery
Autor:
Douglas Miller, Bryony Eagle-Hemming, Sophia Sheikh, Lathishia Joel-David, Adewale Adebayo, Florence Y. Lai, Marius Roman, Tracy Kumar, Hardeep Aujla, Gavin J. Murphy, Marcin J. Woźniak
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract We hypothesised that measuring changes in urinary levels of EV and miR will predict the onset of acute kidney injury in cardiac surgery patients. The study was performed in the cohort of the REVAKI-2 trial. Urine samples were collected befor
Externí odkaz:
https://doaj.org/article/898085908ff74caaa8ccf4f093b6e3f2
Autor:
Adewale S. Adebayo, Marius Roman, Mustafa Zakkar, Syabira Yusoff, Melanie Gulston, Lathishia Joel-David, Bony Anthony, Florence Y. Lai, Antonio Murgia, Bryony Eagle-Hemming, Sophia Sheikh, Tracy Kumar, Hardeep Aujla, Will Dott, Julian L. Griffin, Gavin J. Murphy, Marcin J. Woźniak
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract We hypothesized that body mass index (BMI) dependent changes in myocardial gene expression and energy-related metabolites underlie the biphasic association between BMI and mortality (the obesity paradox) in cardiac surgery. We performed tran
Externí odkaz:
https://doaj.org/article/193eefbb487645909ddb789fcd0c34c3
Autor:
Kristina Tomkova, Marius Roman, Adewale S Adebayo, Sophia Sheikh, Syabira Yusoff, Melanie Gulston, Lathishia Joel-David, Florence Y Lai, Antonio Murgia, Bryony Eagle-Hemming, Hardeep Aujla, Gavin D Richardson, Julian L Griffin, Gavin J Murphy, Marcin J Woźniak
BackgroundTwo-thirds of people over 65 have two or more underlying chronic conditions. Patients with multimorbidities are likely to classify as frail and have worse outcomes after cardiac surgery. We hypothesized that metabolite and transcript profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3f1e0287674af0152207076f5a4748
https://doi.org/10.1101/2023.02.22.23286318
https://doi.org/10.1101/2023.02.22.23286318
Autor:
Gavin J. Murphy, Florence Lai, Tracy Kumar, Riccardo Abbasciano, Cassandra Tutino, Penny Whiting, Alexandra Monaghan, Marcin J Woźniak, Claudio Corazzari
Publikováno v:
Transfusion Medicine Reviews. 35:7-15
Treatment guidelines recommend the routine use of point-of-care diagnostic tests for coagulopathy in the management of cardiac surgery patients at risk of severe bleeding despite uncertainty as to their diagnostic accuracy. We performed a systematic
Autor:
Tracy Kumar, Florence Lai, Anthony B, Marius Roman, William Dott, Bryony Eagle-Hemming, Gavin J. Murphy, Yusoff S, Lathishia Joel-David, Aujla H, Julian L. Griffin, Antonio Murgia, Melanie K. Gulston, Adebayo As, Sheikh S, Marcin J Woźniak
We hypothesized that body mass index (BMI) dependent changes in myocardial gene expression and energy-related metabolites underlie the biphasic association between BMI and mortality (the obesity paradox) in cardiac surgery. We performed transcriptome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3193d1f679db1ba5ca5df7f4d2638f5b
https://doi.org/10.1101/2021.06.29.21259697
https://doi.org/10.1101/2021.06.29.21259697
Autor:
Marcin J Woźniak, Attilio A. Lotto, Lathishia Joel-David, Claire Westrope, Gavin J. Murphy, Tracy Kumar, Paolo Pais, Dawn T. Smallwood, Maria JnTala, Bryony Eagle Hemming, Nikol Sullo, Lorenzo Grazioli, Florence Lai, Claudio Corazzari, Simon Robinson, Gavin Majithia-Beet
Publikováno v:
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 21(4)
Objectives Extracorporeal membrane oxygenation is a treatment for Persistent Pulmonary Hypertension of the Newborn with high mortality. Hypothesis the extracorporeal membrane oxygenation circuit results in inflammatory responses that mitigate against
Publikováno v:
Transfusion. 56:873-877
BACKGROUND Most recently described human platelet antigens (HPAs) have been low-frequency polymorphisms identified in cases of fetomaternal alloimmune thrombocytopenia (FMAIT). There is limited opportunity to study the clinical significance or differ
Autor:
Paolo Pais, Claire Westrope, Dawn T. Smallwood, Attilio A. Lotto, Marcin J Woźniak, Silvia Mariani, Nikol Sullo, Tracy Kumar, Gavin J. Murphy, Maria JnTala
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Objectives: Micro-RNA, small noncoding RNA fragments involved in gene regulation, and microvesicles, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bb336660871869328f694f79b24986
https://doi.org/10.1097/pcc.0000000000001604
https://doi.org/10.1097/pcc.0000000000001604