Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marcin Dembek"'
Autor:
Kyle I. P. Le Huray, Tobias P. Wörner, Tiago Moreira, Marcin Dembek, Maria Reinhardt-Szyba, Paul W. A. Devine, Nicholas J. Bond, Kyle L. Fort, Alexander A. Makarov, Frank Sobott
Publikováno v:
ACS Central Science, Vol 10, Iss 8, Pp 1548-1561 (2024)
Externí odkaz:
https://doaj.org/article/9e01e0a42ddf4a35ab49ce43b62575e8
Autor:
Marcin Dembek, Stephanie E. Willing, Huynh A. Hong, Siamand Hosseini, Paula S. Salgado, Simon M. Cutting
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Clostridium difficile remains a leading nosocomial pathogen, putting considerable strain on the healthcare system. The ability to form endospores, highly resistant to environmental insults, is key to its persistence and transmission. However, importa
Externí odkaz:
https://doaj.org/article/2b9d118fcdb44bff9174da16d6a5353f
Autor:
Marcin Dembek, Lars Barquist, Christine J. Boinett, Amy K. Cain, Matthew Mayho, Trevor D. Lawley, Neil F. Fairweather, Robert P. Fagan
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT Clostridium difficile is the most common cause of antibiotic-associated intestinal infections and a significant cause of morbidity and mortality. Infection with C. difficile requires disruption of the intestinal microbiota, most commonly by
Externí odkaz:
https://doaj.org/article/e216797dfeeb4627b710e0978c35925a
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64011 (2013)
Clostridium difficile is the leading cause of hospital acquired diarrhoea in industrialised countries. Under conditions that are not favourable for growth, the pathogen produces metabolically dormant endospores via asymmetric cell division. These are
Externí odkaz:
https://doaj.org/article/1444389161a84438b7c3af0031d7ea07
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003010 (2012)
The African sleeping sickness parasite Trypanosoma brucei evades the host immune system through antigenic variation of its variant surface glycoprotein (VSG) coat. Although the T. brucei genome contains ∼1500 VSGs, only one VSG is expressed at a ti
Externí odkaz:
https://doaj.org/article/bb9d576f87c644829e8be4d4ff36f30a
Autor:
Claire Barber, Victoria Arena De Souza, Rachel L. Paterson, Magdalena Martin‐Urdiroz, Nitha Charles Mulakkal, Velupillai Srikannathasan, Mary Connolly, Gwilym Phillips, Tein Foong‐Leong, Robert Pengelly, Vijaykumar Karuppiah, Tressan Grant, Marcin Dembek, Anil Verma, Dawn Gibbs‐Howe, Thomas H. Blicher, Andrew Knox, Ross A. Robinson, David K. Cole, Sarah Leonard
Publikováno v:
European Journal of Immunology. 52:618-632
The nonpolymorphic class Ib molecule, HLA-E, primarily presents peptides from HLA class Ia leader peptides, providing an inhibitory signal to NK cells via CD94/NKG2 interactions. Although peptides of pathogenic origin can also be presented by HLA-E t
Autor:
Victor Yin, Paul W.A. Devine, Janet C. Saunders, Alistair Hines, Sam Shepherd, Marcin Dembek, Claire L. Dobson, Joost Snijder, Nicholas J. Bond, Albert J.R. Heck
Recombinant adeno-associated viruses (rAAVs) are the leading platform for in vivo delivery of gene therapies, with several already approved for clinical use. However, the heterogeneity and structural complexity of these viral particles render them ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca0252bb078a80ed44d137a43c320a35
https://doi.org/10.1101/2022.08.27.505551
https://doi.org/10.1101/2022.08.27.505551
Autor:
Wilawan Bunjobpol, Jose Donoso, Michelle L. McCully, Sarah Leonard, Florian U. Seifert, Richard J. Suckling, Dominic W. Hine, Anil Verma, Luis F. Godinho, Mala K. Maini, Tressan Grant, Anshuk Sarkar, Sara Crespillo, Marcin Dembek, Andrew Walker, Bethany Turner, Dawn Howe, Lucy Dorrell, Carole Perot, Zoë Wallace, Praveen K. Singh, Mary M. Connolly, Amanda P. Woon, Kerstin A. Stegmann, Andrew Alexander Knox, Nele Dieckmann, Katrin Wiederhold, Joannah R. Fergusson, Ruth Simmons, Claire Barber, Beak‐San Choi
Publikováno v:
Hepatology (Baltimore, Md.)
Background and aims Therapies for chronic hepatitis B virus (HBV) infection are urgently needed because of viral integration, persistence of viral antigen expression, inadequate HBV-specific immune responses, and treatment regimens that require lifel
Autor:
João M. Monteiro, Adriano O. Henriques, Adam D. Crawshaw, Fátima C. Pereira, Marcin Dembek, Mariana G. Pinho, Paula S. Salgado, Neil F. Fairweather, Mónica Serrano
Publikováno v:
Molecular Microbiology. 100:204-228
Engulfment of the forespore by the mother cell is a universal feature of endosporulation. In Bacillus subtilis, the forespore protein SpoIIQ and the mother cell protein SpoIIIAH form a channel, essential for endosporulation, through which the develop
Autor:
Sarah Leonard, Rachel Paterson, Mauro Monteiro, Joannah Fergusson, David Depoil, Mary Connolly, Sara Crespillo Torreno, Marcin Dembek, Jose Donoso, Tressan Grant, Dominic Hine, Richard Suckling, Zoë Wallace, Andrew Knox, Ruth Martinez Hague, Bethany Turner, Katrin Wiederhold, Stephen Megit, Lucy Dorrell
Publikováno v:
Journal of Hepatology. 73:S883