Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marcin Bielinski"'
Autor:
Harjeet S. Soor, Diego B. Diaz, Ka Yi Tsui, Karina Calvopiña, Marcin Bielinski, Dean J. Tantillo, Christopher J. Schofield, Andrei K. Yudin
Publikováno v:
The Journal of Organic Chemistry. 87:94-102
Amidoboronic acid-containing peptidomimetics are an important class of scaffolds in chemistry and drug discovery. Despite increasing interest in boron-based enzyme inhibitors, constrained amidoboronic acids have received little attention due to the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc918521acf7aef794442f502df2b3a5
https://doi.org/10.1021/acs.joc.1c02015
https://doi.org/10.1021/acs.joc.1c02015
Autor:
Marcin Bielinski, Hannah T Baddock, J.A. Newman, S.M.M. Mukhopadhyay, Peter J. McHugh, Christopher J. Schofield, Opher Gileadi, Angeline E Gavard, Adam A Dannerfjord, Yuliana Yosaatmadja
Publikováno v:
Nucleic Acids Research
Artemis (SNM1C/DCLRE1C) is an endonuclease that plays a key role in development of B- and T-lymphocytes and in dsDNA break repair by non-homologous end-joining (NHEJ). Artemis is phosphorylated by DNA-PKcs and acts to open DNA hairpin intermediates g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c17e074069329b662c5ea0feaf7a5aa
https://doi.org/10.1093/nar/gkab693
https://doi.org/10.1093/nar/gkab693
Autor:
Opher Gileadi, Peter J. McHugh, J.A. Newman, Yuliana Yosaatmadja, Christopher J. Schofield, Marcin Bielinski, Hannah T Baddock
Publikováno v:
Nucleic Acids Research
The SNM1 nucleases which help maintain genome integrity are members of the metallo-β-lactamase (MBL) structural superfamily. Their conserved MBL-β-CASP-fold SNM1 core provides a molecular scaffold forming an active site which coordinates the metal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e38fdb74b5fe545ecfc1086d9718ac1
https://doi.org/10.1093/nar/gkab692
https://doi.org/10.1093/nar/gkab692
Autor:
Hannah T Baddock, Sanja Brolih, Yuliana Yosaatmadja, Malitha Ratnaweera, Marcin Bielinski, Lonnie P Swift, Abimael Cruz-Migoni, Haitian Fan, Jeremy R Keown, Alexander P Walker, Garrett M Morris, Jonathan M Grimes, Ervin Fodor, Christopher J Schofield, Opher Gileadi, Peter J McHugh
Publikováno v:
Nucleic acids research. 50(3)
The SARS-CoV-2 coronavirus is the causal agent of the current global pandemic. SARS-CoV-2 belongs to an order, Nidovirales, with very large RNA genomes. It is proposed that the fidelity of coronavirus (CoV) genome replication is aided by an RNA nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2c066755ee5b2308afcd92c96174c2
https://pubmed.ncbi.nlm.nih.gov/35037045
https://pubmed.ncbi.nlm.nih.gov/35037045
Autor:
Abimael Cruz-Migoni, Sanja Brolih, Peter J. McHugh, Marcin Bielinski, Opher Gileadi, Malitha Ratnaweera, Hannah T Baddock, Garrett M. Morris, Lonnie P. Swift, Yuliana Yosaatmadja, Christopher J. Schofield
The SARS-CoV-2 coronavirus (CoV) causes COVID-19, a current global pandemic. SARS-CoV-2 belongs to an order of Nidovirales with very large RNA genomes. It is proposed that the fidelity of CoV genome replication is aided by an RNA nuclease complex, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b212d49f0dd77b66c80c4debb0646b82
https://doi.org/10.1101/2020.08.13.248211
https://doi.org/10.1101/2020.08.13.248211
