Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Marcin, Imielinski"'
Autor:
Thomas G. Paulson, Patricia C. Galipeau, Kenji M. Oman, Carissa A. Sanchez, Mary K. Kuhner, Lucian P. Smith, Kevin Hadi, Minita Shah, Kanika Arora, Jennifer Shelton, Molly Johnson, Andre Corvelo, Carlo C. Maley, Xiaotong Yao, Rashesh Sanghvi, Elisa Venturini, Anne-Katrin Emde, Benjamin Hubert, Marcin Imielinski, Nicolas Robine, Brian J. Reid, Xiaohong Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Barrett’s esophagus is a pre-malignant condition that can progress to esophageal cancer. Here, the authors carry out whole genome sequencing of samples from patients who did or did not progress to cancer and find that mutations in many genes occur
Externí odkaz:
https://doaj.org/article/a39d500ac4374fad8c2ae054c840d6f0
Autor:
Daniel Butler, Christopher Mozsary, Cem Meydan, Jonathan Foox, Joel Rosiene, Alon Shaiber, David Danko, Ebrahim Afshinnekoo, Matthew MacKay, Fritz J. Sedlazeck, Nikolay A. Ivanov, Maria Sierra, Diana Pohle, Michael Zietz, Undina Gisladottir, Vijendra Ramlall, Evan T. Sholle, Edward J. Schenck, Craig D. Westover, Ciaran Hassan, Krista Ryon, Benjamin Young, Chandrima Bhattacharya, Dianna L. Ng, Andrea C. Granados, Yale A. Santos, Venice Servellita, Scot Federman, Phyllis Ruggiero, Arkarachai Fungtammasan, Chen-Shan Chin, Nathaniel M. Pearson, Bradley W. Langhorst, Nathan A. Tanner, Youngmi Kim, Jason W. Reeves, Tyler D. Hether, Sarah E. Warren, Michael Bailey, Justyna Gawrys, Dmitry Meleshko, Dong Xu, Mara Couto-Rodriguez, Dorottya Nagy-Szakal, Joseph Barrows, Heather Wells, Niamh B. O’Hara, Jeffrey A. Rosenfeld, Ying Chen, Peter A. D. Steel, Amos J. Shemesh, Jenny Xiang, Jean Thierry-Mieg, Danielle Thierry-Mieg, Angelika Iftner, Daniela Bezdan, Elizabeth Sanchez, Thomas R. Campion, John Sipley, Lin Cong, Arryn Craney, Priya Velu, Ari M. Melnick, Sagi Shapira, Iman Hajirasouliha, Alain Borczuk, Thomas Iftner, Mirella Salvatore, Massimo Loda, Lars F. Westblade, Melissa Cushing, Shixiu Wu, Shawn Levy, Charles Chiu, Robert E. Schwartz, Nicholas Tatonetti, Hanna Rennert, Marcin Imielinski, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Here, using clinical samples and autopsy tissues, the authors combine fast-colorimetric test (LAMP) for SARS-CoV-2 infection and large-scale shotgun metatranscriptomics for host, viral, and microbial profiling and provide a map of the viral genetic f
Externí odkaz:
https://doaj.org/article/e049d27579f84e2b9f12b7b11bc7c436
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway
Autor:
Jian Carrot-Zhang, Xiaotong Yao, Siddhartha Devarakonda, Aditya Deshpande, Jeffrey S. Damrauer, Tiago Chedraoui Silva, Christopher K. Wong, Hyo Young Choi, Ina Felau, A. Gordon Robertson, Mauro A.A. Castro, Lisui Bao, Esther Rheinbay, Eric Minwei Liu, Tuan Trieu, David Haan, Christina Yau, Toshinori Hinoue, Yuexin Liu, Ofer Shapira, Kiran Kumar, Karen L. Mungall, Hailei Zhang, Jake June-Koo Lee, Ashton Berger, Galen F. Gao, Binyamin Zhitomirsky, Wen-Wei Liang, Meng Zhou, Sitapriya Moorthi, Alice H. Berger, Eric A. Collisson, Michael C. Zody, Li Ding, Andrew D. Cherniack, Gad Getz, Olivier Elemento, Christopher C. Benz, Josh Stuart, J.C. Zenklusen, Rameen Beroukhim, Jason C. Chang, Joshua D. Campbell, D. Neil Hayes, Lixing Yang, Peter W. Laird, John N. Weinstein, David J. Kwiatkowski, Ming S. Tsao, William D. Travis, Ekta Khurana, Benjamin P. Berman, Katherine A. Hoadley, Nicolas Robine, Matthew Meyerson, Ramaswamy Govindan, Marcin Imielinski
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108784- (2021)
Externí odkaz:
https://doaj.org/article/4264da604a8b4596a7e8b99d914ad26d
Autor:
Francesco Maura, Bachisio Ziccheddu, Jenny Z. Xiang, Bhavneet Bhinder, Joel Rosiene, Federico Abascal, Kylee H. Maclachlan, Kenneth Wha Eng, Manik Uppal, Feng He, Wei Zhang, Qi Gao, Venkata D. Yellapantula, Vicenta Trujillo-Alonso, Sunita I. Park, Matthew J. Oberley, Elizabeth Ruckdeschel, Megan S. Lim, Gerald B. Wertheim, Matthew J. Barth, Terzah M. Horton, Andriy Derkach, Alexandra E. Kovach, Christopher J. Forlenza, Yanming Zhang, Ola Landgren, Craig H. Moskowitz, Ethel Cesarman, Marcin Imielinski, Olivier Elemento, Mikhail Roshal, Lisa Giulino-Roth
Publikováno v:
Blood Cancer Discovery. 4:208-227
The rarity of malignant Hodgkin and Reed Sternberg (HRS) cells in classic Hodgkin lymphoma (cHL) limits the ability to study the genomics of cHL. To circumvent this, our group has previously optimized fluorescence-activated cell sorting to purify HRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92db280bf9e148c37153d90fb56ce22e
https://doi.org/10.1158/2643-3230.bcd-22-0128
https://doi.org/10.1158/2643-3230.bcd-22-0128
Publikováno v:
EBioMedicine, Vol 27, Iss C, Pp 317-328 (2018)
Pathological evaluation of tumor tissue is pivotal for diagnosis in cancer patients and automated image analysis approaches have great potential to increase precision of diagnosis and help reduce human error. In this study, we utilize several computa
Externí odkaz:
https://doaj.org/article/b10a15235dad4b7797a9b1bf027c4dc5
Autor:
Andrew L. H. Webster, Mathijs A. Sanders, Krupa Patel, Ralf Dietrich, Raymond J. Noonan, Francis P. Lach, Ryan R. White, Audrey Goldfarb, Kevin Hadi, Matthew M. Edwards, Frank X. Donovan, Remco M. Hoogenboezem, Moonjung Jung, Sunandini Sridhar, Tom F. Wiley, Olivier Fedrigo, Huasong Tian, Joel Rosiene, Thomas Heineman, Jennifer A. Kennedy, Lorenzo Bean, Rasim O. Rosti, Rebecca Tryon, Ashlyn-Maree Gonzalez, Allana Rosenberg, Ji-Dung Luo, Thomas S. Carroll, Sanjana Shroff, Michael Beaumont, Eunike Velleuer, Jeff C. Rastatter, Susanne I. Wells, Jordi Surrallés, Grover Bagby, Margaret L. MacMillan, John E. Wagner, Maria Cancio, Farid Boulad, Theresa Scognamiglio, Roger Vaughan, Kristin G. Beaumont, Amnon Koren, Marcin Imielinski, Settara C. Chandrasekharappa, Arleen D. Auerbach, Bhuvanesh Singh, David I. Kutler, Peter J. Campbell, Agata Smogorzewska
Publikováno v:
Nature, 612(7940), 495-502. Nature Publishing Group
Nature
Nature
Fanconi anaemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink repair resulting in chromosome breakage1–3. The FA repair pathway protects against endogenous and exogenous carcinogenic aldehydes4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15cd1011ef44b739a461beaa02a1cb6
https://doi.org/10.1038/s41586-022-05253-4
https://doi.org/10.1038/s41586-022-05253-4
Autor:
Jeremy Setton, Kevin Hadi, Huasong Tian, Arnaud Da Cruz Paula, Joel Rosiene, Zi-Ning Choo, Julie Behr, Xiaotong Yao, Olivier Elemento, Britta Weigelt, Nadeem Riaz, Jorge S Reis-Filho, Marcin Imielinski, Simon N Powell
Publikováno v:
Cancer Research. 82:P2-06
Background: Cancer genomes provide a durable record of the genetic alterations that are acquired during normal cell development and carcinogenesis from DNA damage and DNA repair defects. As DNA repair-deficient tumors often become dependent on backup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f75afcceda1ec2934e4a11fd1485a6e
https://doi.org/10.1158/1538-7445.sabcs21-p2-06-04
https://doi.org/10.1158/1538-7445.sabcs21-p2-06-04
Autor:
Lisa Giulino-Roth, Mikhail Roshal, Olivier Elemento, Marcin Imielinski, Ethel Cesarman, Craig H. Moskowitz, Ola Landgren, Yanming Zhang, Christopher J. Forlenza, Alexandra E. Kovach, Andriy Derkach, Terzah M. Horton, Matthew J. Barth, Gerald B. Wertheim, Megan S. Lim, Elizabeth Ruckdeschel, Matthew J. Oberley, Sunita I. Park, Vicenta Trujillo-Alonso, Venkata D. Yellapantula, Qi Gao, Wei Zhang, Feng He, Manik Uppal, Kenneth Wha Eng, Kylee H. Maclachlan, Federico Abascal, Joel Rosiene, Bhavneet Bhinder, Jenny Z. Xiang, Bachisio Ziccheddu, Francesco Maura
R code of our analysis clock like mutational signatures in Hodgkin lymphoma WGS and WES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae1ecef2c571b23aacfe9bfcc819d93
https://doi.org/10.1158/2643-3230.22725557
https://doi.org/10.1158/2643-3230.22725557
Autor:
Lisa Giulino-Roth, Mikhail Roshal, Olivier Elemento, Marcin Imielinski, Ethel Cesarman, Craig H. Moskowitz, Ola Landgren, Yanming Zhang, Christopher J. Forlenza, Alexandra E. Kovach, Andriy Derkach, Terzah M. Horton, Matthew J. Barth, Gerald B. Wertheim, Megan S. Lim, Elizabeth Ruckdeschel, Matthew J. Oberley, Sunita I. Park, Vicenta Trujillo-Alonso, Venkata D. Yellapantula, Qi Gao, Wei Zhang, Feng He, Manik Uppal, Kenneth Wha Eng, Kylee H. Maclachlan, Federico Abascal, Joel Rosiene, Bhavneet Bhinder, Jenny Z. Xiang, Bachisio Ziccheddu, Francesco Maura
The rarity of malignant Hodgkin and Reed Sternberg (HRS) cells in classic Hodgkin lymphoma (cHL) limits the ability to study the genomics of cHL. To circumvent this, our group has previously optimized fluorescence-activated cell sorting to purify HRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e1ca0d1ec539882249eb82a4bd0c73
https://doi.org/10.1158/2643-3230.c.6624659
https://doi.org/10.1158/2643-3230.c.6624659
Autor:
Lisa Giulino-Roth, Mikhail Roshal, Olivier Elemento, Marcin Imielinski, Ethel Cesarman, Craig H. Moskowitz, Ola Landgren, Yanming Zhang, Christopher J. Forlenza, Alexandra E. Kovach, Andriy Derkach, Terzah M. Horton, Matthew J. Barth, Gerald B. Wertheim, Megan S. Lim, Elizabeth Ruckdeschel, Matthew J. Oberley, Sunita I. Park, Vicenta Trujillo-Alonso, Venkata D. Yellapantula, Qi Gao, Wei Zhang, Feng He, Manik Uppal, Kenneth Wha Eng, Kylee H. Maclachlan, Federico Abascal, Joel Rosiene, Bhavneet Bhinder, Jenny Z. Xiang, Bachisio Ziccheddu, Francesco Maura
All supplementary figures S1-S17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31feadbbcf51ef0753fcd7473a02c453
https://doi.org/10.1158/2643-3230.22725554
https://doi.org/10.1158/2643-3230.22725554