The pro-inflammatory cytokines IL-1β and IL-6 promote upregulation of the ST6GAL1 sialyltransferase in pancreatic cancer cells.

Autor: Silva AD; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Hwang J; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Marciel MP; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Bellis SL; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA. Electronic address: bellis@uab.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Oct; Vol. 300 (10), pp. 107752. Date of Electronic Publication: 2024 Sep 12.

Role of tumor cell sialylation in pancreatic cancer progression.

Autor: Marciel MP; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States., Haldar B; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States., Hwang J; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States., Bhalerao N; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States., Bellis SL; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States. Electronic address: bellis@uab.edu.

Publikováno v: Advances in cancer research [Adv Cancer Res] 2023; Vol. 157, pp. 123-155. Date of Electronic Publication: 2022 Sep 27.

Upregulated ethanolamine phospholipid synthesis via selenoprotein I is required for effective metabolic reprogramming during T cell activation.

Autor: Ma C; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Hoffmann FW; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Marciel MP; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Page KE; Department of Natural Sciences, Hawaii Pacific University, Kaneohe, HI 96744, USA., Williams-Aduja MA; Department of Natural Sciences, Hawaii Pacific University, Kaneohe, HI 96744, USA., Akana ENL; Department of Natural Sciences, Hawaii Pacific University, Kaneohe, HI 96744, USA., Gojanovich GS; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Gerschenson M; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Urschitz J; Department of Anatomy, Physiology and Biochemistry, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Moisyadi S; Department of Anatomy, Physiology and Biochemistry, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Khadka VS; Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Rozovsky S; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA., Deng Y; Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA., Horgen FD; Department of Natural Sciences, Hawaii Pacific University, Kaneohe, HI 96744, USA., Hoffmann PR; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA. Electronic address: peterrh@hawaii.edu.

Publikováno v: Molecular metabolism [Mol Metab] 2021 May; Vol. 47, pp. 101170. Date of Electronic Publication: 2021 Jan 20.

Targeting the C-terminus of galectin-9 induces mesothelioma apoptosis and M2 macrophage depletion.

Autor: Bertino P; Department of Cell and Molecular Biology, Honolulu, HI, USA., Premeaux TA; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA., Fujita T; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA., Haun BK; Department of Cell and Molecular Biology, Honolulu, HI, USA., Marciel MP; Department of Cell and Molecular Biology, Honolulu, HI, USA., Hoffmann FW; Department of Cell and Molecular Biology, Honolulu, HI, USA., Garcia A; Department of Microbiology and Biotechnology, Kapi'olani Community College, Honolulu, HI, USA., Yiang H; University of Hawai'i Cancer Center, University of Hawai'i, Honolulu, HI, USA., Pastorino S; University of Hawai'i Cancer Center, University of Hawai'i, Honolulu, HI, USA., Carbone M; University of Hawai'i Cancer Center, University of Hawai'i, Honolulu, HI, USA., Niki T; Department of Immunology and Immunopathology, Faculty of Medicine, Kagawa University, Kagawa, Japan.; GalPharma, Co., Ltd., Takamatsu, Japan., Berestecky J; Department of Microbiology and Biotechnology, Kapi'olani Community College, Honolulu, HI, USA., Hoffmann PR; Department of Cell and Molecular Biology, Honolulu, HI, USA., Ndhlovu LC; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA.

Publikováno v: Oncoimmunology [Oncoimmunology] 2019 Apr 17; Vol. 8 (8), pp. 1601482. Date of Electronic Publication: 2019 Apr 17 (Print Publication: 2019).

Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis.

Autor: Marciel MP; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A., Khadka VS; Bioinformatics Core in the Department of Complementary and Integrative Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A., Deng Y; Bioinformatics Core in the Department of Complementary and Integrative Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A., Kilicaslan P; Biotechnology Department, University of Applied Sciences Mannheim, Mannheim, Germany., Pham A; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A., Bertino P; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A., Lee K; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A., Chen S; Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, U.S.A., Glibetic N; The University of Hawaii Cancer Center, Honolulu, Hawaii, U.S.A., Hoffmann FW; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A., Matter ML; The University of Hawaii Cancer Center, Honolulu, Hawaii, U.S.A., Hoffmann PR; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, U.S.A.

Publikováno v: Oncotarget [Oncotarget] 2018 Feb 03; Vol. 9 (17), pp. 13407-13422. Date of Electronic Publication: 2018 Feb 03 (Print Publication: 2018).