Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marcia Roy"'
Publikováno v:
eLife, Vol 6 (2017)
The genetic mechanisms regulating the brain and behaviour across the lifespan are poorly understood. We found that lifespan transcriptome trajectories describe a calendar of gene regulatory events in the brain of humans and mice. Transcriptome trajec
Externí odkaz:
https://doaj.org/article/abb53584a758407eb234ffdf29f59d44
Autor:
Marcia Roy, Oksana Sorokina, Colin McLean, Silvia Tapia-González, Javier DeFelipe, J. Douglas Armstrong, Seth G. N. Grant
Publikováno v:
Proteomes, Vol 6, Iss 3, p 31 (2018)
The proteome of the postsynaptic terminal of excitatory synapses comprises over one thousand proteins in vertebrate species and plays a central role in behavior and brain disease. The brain is organized into anatomically distinct regions and whether
Externí odkaz:
https://doaj.org/article/4aeb597e33124f3599b0dc1b5c1fc9e2
Autor:
Seth G. N. Grant, Colin Mclean, J. Douglas Armstrong, Marcia Roy, Javier DeFelipe, Oksana Sorokina, Silvia Tapia-González
Publikováno v:
Proteomes, Vol 6, Iss 3, p 31 (2018)
Proteomes
Roy, M, Sorokina, O, McLean, C, Tapia-González, S, DeFelipe, J, Armstrong, J D & Grant, S 2018, ' Regional Diversity in the Postsynaptic Proteome of the Mouse Brain ', Proteomes, vol. 6, no. 3 . https://doi.org/10.3390/proteomes6030031
Volume 6
Issue 3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Proteomes
Roy, M, Sorokina, O, McLean, C, Tapia-González, S, DeFelipe, J, Armstrong, J D & Grant, S 2018, ' Regional Diversity in the Postsynaptic Proteome of the Mouse Brain ', Proteomes, vol. 6, no. 3 . https://doi.org/10.3390/proteomes6030031
Volume 6
Issue 3
Digital.CSIC. Repositorio Institucional del CSIC
instname
The proteome of the postsynaptic terminal of excitatory synapses comprises over one thousand proteins in vertebrate species and plays a central role in behavior and brain disease. The brain is organized into anatomically distinct regions and whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a76bb32d4c66b3574d455291d90b04
Publikováno v:
Mangani, C, Lilienkampf, A, Roy, M, de Sousa, P A & Bradley, M 2015, ' Thermoresponsive hydrogel maintains the mouse embryonic stem cell "naïve" pluripotency phenotype ', Biomaterials science, vol. 3, no. 10, pp. 1371-5 . https://doi.org/10.1039/c5bm00121h
A chemically defined thermoresponsive hydrogel, poly(AEtMA-Cl-co-DEAEA) cross-linked with N,N'-methylenebisacrylamide, which allows enzyme-free passaging, was used as a substrate to culture murine embryonic stem cells (mESCs) under defined and undefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bafb560a1ff8d6e54e4b6c0ffbbc6d
https://doi.org/10.1039/c5bm00121h
https://doi.org/10.1039/c5bm00121h
Autor:
Paula Tennant, Sephra Rampersad, Angela Alleyne, Lloyd Johnson, Deiondra Tai, Icolyn Amarakoon, Marcia Roye, Patrice Pitter, Peta-Gaye Chang, Lisa Myers Morgan
Publikováno v:
Viruses, Vol 16, Iss 4, p 603 (2024)
Viruses pose major global challenges to crop production as infections reduce the yield and quality of harvested products, hinder germplasm exchange, increase financial inputs, and threaten food security. Small island or archipelago habitat conditions
Externí odkaz:
https://doaj.org/article/de5af7ba6e4c410c9e91cfac4c43cf0d
Publikováno v:
eLife, Vol 6 (2017)
Skene, N G, Roy, M & Grant, S G N 2017, ' A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia ', eLIFE, vol. 6, e17915 . https://doi.org/10.7554/eLife.17915
eLife
Skene, N G, Roy, M & Grant, S G N 2017, ' A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia ', eLIFE, vol. 6, e17915 . https://doi.org/10.7554/eLife.17915
eLife
The genetic mechanisms regulating the brain and behaviour across the lifespan are poorly understood. We found that lifespan transcriptome trajectories describe a calendar of gene regulatory events in the brain of humans and mice. Transcriptome trajec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bed9d2d938a6d236441ac048b7fbb1
https://elifesciences.org/articles/17915
https://elifesciences.org/articles/17915
Autor:
Clemence Simonnet, Marcia Roy, Nathan G. Skene, Ruud Zwart, Francesca Mazzo, Oksana Sorokina, J. Douglas Armstrong, Emanuele Sher, Seth G. N. Grant, Colin Smith
Publikováno v:
Roy, M, Sorokina, O, Skene, N, Simonnet, C, Mazzola, F, Zwart, R, Sher, E, Smith, C, Armstrong, J D & Grant, S 2018, ' Proteomic analysis of postsynaptic proteins in regions of the human neocortex ', Nature Neuroscience, vol. 21, no. 1, pp. 130–138 . https://doi.org/10.1038/s41593-017-0025-9
The postsynaptic proteome of excitatory synapses comprises ~1,000 highly conserved proteins that control the behavioral repertoire and mutations disrupting their function cause >130 brain diseases. Here, we document the composition of postsynaptic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d957b11a9cbe422d4e1ac1a7993e780c
https://pubmed.ncbi.nlm.nih.gov/29203896
https://pubmed.ncbi.nlm.nih.gov/29203896
Autor:
Sonam Dolma, Emma Griffiths, Marcia Roy, Mike Tyers, Nick Jarvik, Jan Wildenhain, R. L. White, Michaela Spitzer, David S. Bellows, Gerard D. Wright
Publikováno v:
Scientific Data
The network structure of biological systems suggests that effective therapeutic intervention may require combinations of agents that act synergistically. However, a dearth of systematic chemical combination datasets have limited the development of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e050345db9ea09f6aaae92f757696010
https://doi.org/10.1038/sdata.2016.95
https://doi.org/10.1038/sdata.2016.95
Publikováno v:
Kanonidis, E I, Roy, M M, Deighton, R F & Le Bihan, T 2016, ' Protein Co-Expression Analysis as a Strategy to Complement a Standard Quantitative Proteomics Approach : Case of a Glioblastoma Multiforme Study ', PLoS ONE, vol. 11, no. 8, pp. e0161828 . https://doi.org/10.1371/journal.pone.0161828
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161828 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161828 (2016)
Although correlation network studies from co-expression analysis are increasingly popular, they are rarely applied to proteomics datasets. Protein co-expression analysis provides a complementary view of underlying trends, which can be overlooked by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d50a956f8e1f6d8737b47b99d44f6d
https://www.pure.ed.ac.uk/ws/files/27676557/Deighton_R_Protein_co_expression....pdf
https://www.pure.ed.ac.uk/ws/files/27676557/Deighton_R_Protein_co_expression....pdf