Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Marcia L, Hart"'
Autor:
Giancarlo R. Valiente, Armin Munir, Marcia L. Hart, Perry Blough, Takuma T. Wada, Emma E. Dalan, William L. Willis, Lai-Chu Wu, Aharon G. Freud, Wael N. Jarjour
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The gut microbiota (GM) exerts a strong influence over the host immune system and dysbiosis of this microbial community can affect the clinical phenotype in chronic inflammatory conditions. To explore the role of the GM in lupus nephritis, w
Externí odkaz:
https://doaj.org/article/3eb3b055698a4551972032c615d72505
Autor:
Aaron C. Ericsson, Marcia L. Hart, Jessica Kwan, Louise Lanoue, Lynette R. Bower, Renee Araiza, K. C. Kent Lloyd, Craig L. Franklin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Ericsson et al. show that different vendors (suppliers of mouse strains) harbor distinct microbiomes, which drive distinct behavioral phenotypes when the genetics are fixed. They specifically focus on changes relating to exploratory and anxiety-relat
Externí odkaz:
https://doaj.org/article/31cee5810a5f4047a8f974fafbfdccee
Autor:
Jacob E. Moskowitz, Anthony G. Doran, Zhentian Lei, Susheel B. Busi, Marcia L. Hart, Craig L. Franklin, Lloyd W. Sumner, Thomas M. Keane, James M. Amos-Landgraf
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background Colorectal cancer (CRC) is a multifactorial disease resulting from both genetic predisposition and environmental factors including the gut microbiota (GM), but deciphering the influence of genetic variants, environmental variables
Externí odkaz:
https://doaj.org/article/bd1bbd159a3648aba4ca021fd4b67bcd
Autor:
Angela B. Javurek, Dhananjay Suresh, William G. Spollen, Marcia L. Hart, Sarah A. Hansen, Mark R. Ellersieck, Nathan J. Bivens, Scott A. Givan, Anandhi Upendran, Raghuraman Kannan, Cheryl S. Rosenfeld
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Due to their antimicrobial properties, silver nanoparticles (AgNPs) are being used in non-edible and edible consumer products. It is not clear though if exposure to these chemicals can exert toxic effects on the host and gut microbiome. Conf
Externí odkaz:
https://doaj.org/article/0c97909e60b44dc2a6a5ac86c7478e9c
Autor:
Sarah A. Hansen, Marcia L. Hart, Susheel Busi, Taybor Parker, Angela Goerndt, Kevin Jones, James M. Amos-Landgraf, Elizabeth C. Bryda
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 10, Pp 1139-1146 (2016)
Somatic mutations in the Tp53 tumor suppressor gene are the most commonly seen genetic alterations in cancer, and germline mutations in Tp53 predispose individuals to a variety of early-onset cancers. Development of appropriate translational animal m
Externí odkaz:
https://doaj.org/article/c44d778660ec4797abaeee789dcd0c14
Autor:
Marcus J. Crim, Marcia L. Hart
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626580
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0f169d79f1a040e108c0382267e32dc
https://doi.org/10.1007/978-1-0716-2659-7_3
https://doi.org/10.1007/978-1-0716-2659-7_3
Autor:
Marcus J, Crim, Marcia L, Hart
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2562
Laboratory animal health monitoring programs are necessary to protect animal health and welfare, the validity of experimental data, and human health against zoonotic infections. Health monitoring programs should be designed based on a risk assessment
Autor:
Craig L. Franklin, Renee S. Araiza, Aaron C. Ericsson, Louise Lanoue, Marcia L. Hart, Lynette Bower, Kent Lloyd, Jessica Y. Kwan
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology, vol 4, iss 1
Communications Biology
Communications Biology, vol 4, iss 1
The mouse is the most commonly used model species in biomedical research. Just as human physical and mental health are influenced by the commensal gut bacteria, mouse models of disease are influenced by the fecal microbiome (FM). The source of mice r
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
It is estimated that 1.4 million people in the United States suffer from Inflammatory Bowel Disease (IBD), with an overall annual health care cost of more than $1.7 billion. Although the exact etiology of this disease remains unknown, research sugges
Externí odkaz:
https://doaj.org/article/8186fb0cadfe45f99f3bdcb801572566
Autor:
Amy A. Irving, Kazuto Yoshimi, Marcia L. Hart, Taybor Parker, Linda Clipson, Madeline R. Ford, Takashi Kuramoto, William F. Dove, James M. Amos-Landgraf
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1215-1225 (2014)
Prior to the advent of genetic engineering in the mouse, the rat was the model of choice for investigating the etiology of cancer. Now, recent advances in the manipulation of the rat genome, combined with a growing recognition of the physiological di
Externí odkaz:
https://doaj.org/article/e627bb63238d47cfbb1f092913536550