Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marcia K. Schmehl"'
Publikováno v:
Cryobiology. 30:164-171
To determine if antibiotic solutions for potential use in antimicrobial treatment of tissues were detrimental to cell viability, canine saphenous veins were exposed to three different antibiotic solutions at 37 degrees C for 12 h. Viability was deter
Autor:
Michael Darcy, Robert Warner, Marcia K. Schmehl, John S. Metcalf, Harvey L. Bank, Michael F. Pratt, Marcus S. Albernaz
Publikováno v:
Journal of Surgical Research. 50:57-64
Local vascular reconstructions frequently require the use of vein grafts to bridge arterial or venous defects. Most previous studies on the use of cryopreserved veins have used relatively large caliber vessels. There have been few studies on the effe
Publikováno v:
In Vitro Cellular & Developmental Biology. 26:1035-1042
The validity of limiting dilution assays can be compromised or negated by the use of statistical methodology which does not consider all issues surrounding the biological process. This study critically evaluates statistical methods for estimating the
Publikováno v:
Communications in Statistics - Theory and Methods. 19:2643-2666
The statistical problems associated with estimating the mean responding cell density in the limiting dilution assay (LDA) have largely been ignored. We evaluate techniques for analyzing LDA data from multiple biological samples, assumed to follow eit
Publikováno v:
Biometrics. 49:491
SUMMARY Confidence intervals for the relative frequency of responding cells in limiting dilution assays (LDAs) have not been examined closely. Generally, confidence intervals are calculated by using the normal approximation, sometimes preceded by a l
Publikováno v:
Cryobiology. 26:239-247
Scientists frequently must choose between several different statistical methods for analyzing data. Monte Carlo simulations and power analyses can be used to select the most appropriate statistical method for analyzing viability assay data and to cho
Autor:
Harvey L. Bank, Marcia K. Schmehl
Publikováno v:
Cryobiology. 26:203-211
The selection of appropriate viability assays is critical in evaluating the efficacy of any cryopreservation procedure. The appropriateness of a given assay depends on the specific tissue and the function which is being optimized. Although a broad ra
Publikováno v:
The Laryngoscope. 99:1020-1026
Microvascular techniques offer important alternatives for reconstructive head and neck surgery. To test the viability of freeze-dried allografts, a pilot experimental study was performed using the rabbit model. Freeze-dried preserved arterial allogra
Publikováno v:
In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. 25(1)
This study reports the results of a critical comparison of five statistical methods for estimating the density of viable cells in a limiting dilution assay (LDA). Artificial data were generated using Monte Carlo simulation. The performance of each st
Publikováno v:
In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. 25(1)
Six different statistical methods for comparing limiting dilution assays were evaluated, using both real data and a power analysis of simulated data. Simulated data consisted of a series of 12 dilutions for two treatment groups with 24 cultures per d