Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marcia I. Heron"'
Autor:
Kaliappan Iyanar, Jessica D. Dietz, Graciela B. Arhancet, Horng-Chih Huang, Danny J. Garland, Marcia I. Heron, Silvia I. Pomposiello, Xiao Hu, Len F. Lee, Joe T. Collins, Scott S. Woodard, James Robert Blinn, Maria A. Payne, Brenda L. Case, Rhonda S. Woerndle
Publikováno v:
Journal of Medicinal Chemistry. 53:5970-5978
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9288e4053ed7e7f775bce265c4ec3184
https://doi.org/10.1021/jm100506y
https://doi.org/10.1021/jm100506y
Autor:
J. Randall Slemmon, Karen Kaup, Sashi Nadanaciva, Rachel Scherrer, Virginia Casadas, Florentina Catana, You Yang Zhao, Marcia I. Heron, Cory L. Painter
Publikováno v:
Journal of Chromatography B. 819:219-228
Proteomic strategies have continued to demonstrate value in studying disease by exploiting new technologies that can develop significant numbers of measurements from single samples. However, using complex samples such as tissues or blood has continue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b4812bbf9309089dd9a23a46cba310
https://doi.org/10.1016/j.jchromb.2004.08.005
https://doi.org/10.1016/j.jchromb.2004.08.005
Publikováno v:
Microvascular Research. 58:183-186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cdd488bfb3f57949fdb8e65c9495de
https://doi.org/10.1006/mvre.1999.2170
https://doi.org/10.1006/mvre.1999.2170
Publikováno v:
Journal of Molecular and Cellular Cardiology. 29:1045-1054
Changes in tissue structure of hearts undergoing atrophy following heterotopic isotransplantation were studied. Both normal and hypertrophic hearts were used, originating from male and female rats. Aortic constriction produced in newborn rats, result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a567cdd7105ddf08181ff17895a27fc0
https://doi.org/10.1006/jmcc.1996.0350
https://doi.org/10.1006/jmcc.1996.0350
Publikováno v:
Cardiovascular Research. 33:230-240
Objective: The aim of the present study was two-fold: (1) to examine the effect of hyper- and hypothyroidism on the developing coronary capillary network in neonatal rats, and (2) to determine in adult rats that had re-established euthyroid status wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57fb9b41b6bdbe1fc21d740d68a2700
https://doi.org/10.1016/s0008-6363(96)00198-8
https://doi.org/10.1016/s0008-6363(96)00198-8
Publikováno v:
Journal of Morphology. 216:35-45
The fiber architecture of adult human sartorius and gracilis muscles was examined using a combination of fiber microdissections and histological methods. Intact fibers were dissected from fascicles of muscle strips that were digested in nitric acid.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dce7b18047ff3c96dd55ad972182613
https://doi.org/10.1002/jmor.1052160106
https://doi.org/10.1002/jmor.1052160106
Autor:
Chris P. Carron, Madeleine H. Li, Daniel P. Becker, T. Sunyer, John N. Freskos, Louis J. Bedell, Boehm Terri L, Chris L. Funckes-Shippy, Decrescenzo Gary A, Clara I. Villamil, Joseph J. McDonald, Grace E. Munie, Jeffery N. Carroll, Pramod P. Mehta, Jun Yao, Brian R. Bond, Craig Swearingen, Jennifer M. Williams, Barta Thomas E, Marcia I. Heron, Dean Welsch, Karl J. Mathis, Carol Pearcy Howard, James R. Kiefer, Susan L. Hockerman, Alan M. Easton, Ying Yu
Publikováno v:
Journal of medicinal chemistry. 53(18)
α-Sulfone-α-piperidine and α-tetrahydropyranyl hydroxamates were explored that are potent inhibitors of MMP's-2, -9, and -13 that spare MMP-1, with oral efficacy in inhibiting tumor growth in mice and left-ventricular hypertrophy in rats and in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9685357a0ce79c92aebc66064d268699
https://pubmed.ncbi.nlm.nih.gov/20726512
https://pubmed.ncbi.nlm.nih.gov/20726512
Autor:
David B. Reitz, Xiangyang Chen, James Robert Blinn, Horng-Chih Huang, Kevin F. McGee, Shengtian Yang, Marvin J. Meyers, Jessica D. Dietz, Danny J. Garland, Joseph R. Rico, Graciela B. Arhancet, Joe T. Collins, Maria A. Payne, Matthew W. Mahoney, Susan L. Hockerman, Marcia I. Heron, Xiao Hu, Bruce L. Homer, Scott A. Long, Jay M. Wendling
Publikováno v:
Journal of medicinal chemistry. 53(16)
We have discovered a novel class of nonsteroidal pyrazoline antagonists of the mineralocorticoid receptor (MR) that show excellent potency and selectivity against other nuclear receptors. Early analogues were poorly soluble and had a propensity to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f050d0c3dc870966f983df9d6dea1c
https://pubmed.ncbi.nlm.nih.gov/20672822
https://pubmed.ncbi.nlm.nih.gov/20672822
Autor:
Marcia I. Heron, Charles W. Bolten
Publikováno v:
Endocrinology. 147(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7375fef78449f9277c7c705ef0ac58
https://pubmed.ncbi.nlm.nih.gov/16601137
https://pubmed.ncbi.nlm.nih.gov/16601137
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461357636
A better knowledge of oxygen transport to tissue requires accurate, reliable quantification and modelling of a tissue’s vascular supply. Understanding the geometry of the capillary network is of particular importance, since capillaries are the regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b00ff35c315b10f79284345e2021f79
https://doi.org/10.1007/978-1-4615-1875-4_73
https://doi.org/10.1007/978-1-4615-1875-4_73
