Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marcia E. Christy"'
Autor:
P. Gautheron, Pierre Mallorga, Marcia E. Christy, Gerald S. Ponticello, Jeffrey Grove, Michael F. Sugrue, M P Viader, John J. Baldwin, Harvey Schwam
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 6:9-22
MK-927 (dl-5,6-dihydro-4-(2-methylpropylamino)-4H-thieno(2,3b)thiopyra n-2-sulfonamide-7,7-dioxide hydrochloride) is a water soluble, carbonic anhydrase inhibitor (CAI) possessing a Ki of 12.0 nM against purified human carbonic anhydrase II in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f2eee62bcd73a5048f4255a858555a
https://doi.org/10.1089/jop.1990.6.9
https://doi.org/10.1089/jop.1990.6.9
Autor:
Marcia E. Christy, Robert L. Smith, Anthony M. Smith, J. M. Sondey, K. M. Strohmaier, P. Gautheron, Samuel L. Graham, Stuart R. Michelson, P. A. Lyle, Gerald S. Ponticello, C. M. Robb, D. B. Best, J. M. Hoffman, M. F. Sugrue, Kenneth L. Shepard, Mark B. Freedman, P. S. Anderson, John J. Baldwin, C. N. Habecker, Harvey Schwam, Sandor L. Varga
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb14c5e88db3a417b1974766bb6325c7
https://doi.org/10.1002/chin.199017166
https://doi.org/10.1002/chin.199017166
Publikováno v:
Tetrahedron Letters. 16:2553-2556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::747f711136ed7d7480b545b23ab9e2bc
https://doi.org/10.1016/s0040-4039(00)75176-8
https://doi.org/10.1016/s0040-4039(00)75176-8
Autor:
Ben E. Evans, Paul S. Anderson, Marcia E. Christy, C. Dylion Colton, David C. Remy, Kenneth E. Rittle, Edward L. Engelhardt
Publikováno v:
The Journal of Organic Chemistry. 44:3127-3135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec32cd685212a9cb287258dbf2bfd8a3
https://doi.org/10.1021/jo01332a008
https://doi.org/10.1021/jo01332a008
Autor:
C. Dylion Colton, Paul S. Anderson, Gerald S. Ponticello, Marcia E. Christy, Wasyl Halczenko, Kenneth L. Shepard
Publikováno v:
The Journal of Organic Chemistry. 44:1519-1533
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aac8cd93b62fdba8150283236335afbd
https://doi.org/10.1021/jo01323a032
https://doi.org/10.1021/jo01323a032
Autor:
John J. Baldwin, Marcia E. Christy, George H. Denny, Charles N. Habecker, Mark B. Freedman, Paulette A. Lyle, Gerald S. Ponticello, Sandor L. Varga, Dennis M. Gross, Charles S. Sweet
Publikováno v:
Journal of Medicinal Chemistry. 29:1065-1080
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96caf3429d0bea07914a779923304d81
https://doi.org/10.1021/jm00156a028
https://doi.org/10.1021/jm00156a028
Publikováno v:
Tetrahedron Letters. 17:3673-3676
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3e9b16683832a5bb0dedb26d8f18ff6
https://doi.org/10.1016/s0040-4039(00)93078-8
https://doi.org/10.1016/s0040-4039(00)93078-8
Autor:
W. C. Randall, Michael F. Sugrue, Gerald S. Ponticello, Harvey Schwam, Marcia E. Christy, P. S. Anderson, John J. Baldwin, James P. Springer, Murcko Mark A, P. Gautheron
Publikováno v:
Journal of Medicinal Chemistry. 32:2510-2513
The bulk of aqueous humor entering the eye is produced through an active secretory process by the nonpigmented epithelial cells of the ciliary process. Carbonic anhydrase is present in these cells, and following inhibition of the enzyme, bicarbonate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970a34dcbdf4e2bfaaf323ca837077b8
https://doi.org/10.1021/jm00132a003
https://doi.org/10.1021/jm00132a003
Publikováno v:
Life Sciences. 30:1565-1571
A relatively mild hyperactive state (HAS), characterized by agitation and hypermotility, is induced by opiate drugs and opioid peptides in general and is blocked by naloxone. HAS can be distinguished from the profound hyperresponsiveness of an explos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68f682b2e3e573c2d7d469e317f0397
https://doi.org/10.1016/0024-3205(82)90245-4
https://doi.org/10.1016/0024-3205(82)90245-4
Publikováno v:
The Journal of Organic Chemistry. 43:4311-4315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a1c2153517710eb0b5af0c28dc889c
https://doi.org/10.1021/jo00416a013
https://doi.org/10.1021/jo00416a013