Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marcia Applegate"'
Autor:
Jeffrey R. Sawyer, Marcia Applegate, Martha M. Moore, Natalie Carley, John C. Hozier, Donald Clive, Jane Scalzi
Publikováno v:
Genomics. 10:827-830
We report the cytogenetic mapping of the thymidine kinase ( tk-1 ) gene in the mouse using two complementary and independent analyses: (1) investigation of chromosome aberrations associated with tk-1 gene inactivation in the L5178Y TK +/− −3.7.2C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0064c3712c367dbd7f346223e2857cb
https://doi.org/10.1016/0888-7543(91)90469-u
https://doi.org/10.1016/0888-7543(91)90469-u
Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells
Autor:
A Burrell, A Wadhams, Martha M. Moore, C B Broder, G Juhn, P F Lin, K L Kasweck, John C. Hozier, Marcia Applegate
Publikováno v:
Proceedings of the National Academy of Sciences. 87:51-55
The mouse lymphoma L5178Y TK+/- 3.7.2C cell line allows quantitation of induced TK(+/-)----TK-/- mutations at the heterozygous thymidine kinase (Tk) locus. TK-/- mutant colonies show a bimodal size distribution, reflecting a difference in the growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000e0a74f5e59367f9c450272a371d3a
https://doi.org/10.1073/pnas.87.1.51
https://doi.org/10.1073/pnas.87.1.51
Publikováno v:
Mutation research. 270(2)
Recently in vitro assays of mutagenesis have been criticized as being poorly predictive of long-term in vivo rodent assays of carcinogenicity. Questions have also been raised concerning the relevance of rodent assays to human risk. In vitro assays us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95397c2349ff377cc89f7669d0c9376d
https://pubmed.ncbi.nlm.nih.gov/1383737
https://pubmed.ncbi.nlm.nih.gov/1383737