Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marcia Alvarez Fernandez"'
Autor:
Ariane L Herrick, Andrea Murray, Graham Dinsdale, Joanne Manning, Chukwuma Chukwu, Marcia Alvarez Fernandez, James R Seibold, Fredrik Tiberg
Publikováno v:
Rheumatology. 62
Background/Aims Prostacyclin analogues, although effective treatment for systemic sclerosis (SSc)-related Raynaud’s phenomenon (RP), have the disadvantage of requiring intravenous or subcutaneous (SC) infusion. Treprostinil subcutaneous depot (CAM2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77b0aa36efe95880fbd6a5ec7d6ed7d
https://doi.org/10.1093/rheumatology/kead104.190
https://doi.org/10.1093/rheumatology/kead104.190
Publikováno v:
Journal of Biological Chemistry; 280(18), pp 18221-18228 (2005)
Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. Cystatin D is a type 2 cystatin, a secreted inhibitor found in human saliva and tear fluid. Compared to its homologues, cystatin D pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9269fdee835fc6856e29aef238bf48f7
https://doi.org/10.1074/jbc.m411914200
https://doi.org/10.1074/jbc.m411914200
Autor:
Elżbieta Jankowska, Mariusz Jaskolski, Magnus Abrahamson, Anders Grubb, Marcia Alvarez Fernandez, Zbigniew Grzonka, Robert Janowski, Maciej Kozak
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
Human cystatin C, a protein with amyloidogenic properties and a potent inhibitor of papain-like mammalian proteases, has been produced in its full-length form by recombinant techniques and crystallized in two polymorphic forms: cubic and tetragonal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cb1eb435c448a07a36ad38952e408e
https://doi.org/10.1107/s090744499901121x
https://doi.org/10.1107/s090744499901121x
Autor:
Bernd Gerhartz, Magnus Abrahamson, Marcia Alvarez-Fernandez, Pam M. Dando, Alan John Barrett, Jian Ni
Publikováno v:
Journal of Biological Chemistry. 274:19195-19203
We have investigated the inhibition of the recently identified family C13 cysteine peptidase, pig legumain, by human cystatin C. The cystatin was seen to inhibit enzyme activity by stoichiometric 1:1 binding in competition with substrate. The Ki valu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44d945a36f5e128506ac89f93ca960d
https://doi.org/10.1074/jbc.274.27.19195
https://doi.org/10.1074/jbc.274.27.19195
Autor:
Mariusz Jaskolski, Magnus Abrahamson, A. Ljunggren, Marcia Alvarez-Fernandez, Grzegorz Bujacz, John S. Mort, Joanne C. Krupa, Izabela Redzynia
Publikováno v:
Journal of Molecular Biology; 371(1), pp 137-153 (2007)
Chagasin is a protein produced by Trypanosoma cruzi, the parasite that causes Chagas' disease. This small protein belongs to a recently defined family of cysteine protease inhibitors. Although resembling well-known inhibitors like the cystatins in si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a528d4ef1a0cd20b6cd205e108fdd5
https://lup.lub.lu.se/record/539868
https://lup.lub.lu.se/record/539868
Publikováno v:
Biochemical Society symposium. (70)
Chicken egg white cystatin was first described in the late 1960s. Since then, our knowledge about a superfamily of similar proteins present in mammals, birds, fish, insects, plants and some protozoa has expanded, and their properties as potent peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc85815ebb0b94cf009c871e98a29133
https://pubmed.ncbi.nlm.nih.gov/14587292
https://pubmed.ncbi.nlm.nih.gov/14587292