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pro vyhledávání: '"Marci, Koko"'
Autor:
Andrew, Fensome, Marci, Koko, Jay, Wrobel, Puwen, Zhang, Zhiming, Zhang, Jeffrey, Cohen, Scott, Lundeen, Kelly, Rudnick, Yuan, Zhu, Richard, Winneker
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(7)
During the course of our studies on 3,3-disubstituted-5-aryloxindoles derived progesterone receptor (PR) antagonists we discovered that changing the amide funtionality to a thio-amide resulted in compounds displaying potent PR agonist activity. In th