Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marcelo V. Negrão"'
Autor:
Daniel M. Girardi, Mariana A. de Lima, Gabriel C. B. Pereira, Marcelo V. Negrão, Rossana V. M. López, Fernanda C. Capareli, Jorge Sabbaga, Paulo Marcelo G. Hoff
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background Treatment of localized gastric cancer (LGC) consists of surgical resection followed by adjuvant treatment. Both chemoradiation (CRT) and chemotherapy (CT) regimens have shown benefit in survival outcomes versus observation. Howeve
Externí odkaz:
https://doaj.org/article/76bb3fdc7ade44489835116eec73b541
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract In this review, we cover the current understanding of BRAF mutations and associated clinical characteristics in patients with metastatic NSCLC, approved and emerging treatment options, BRAF sequencing approaches, and unmet needs. The BRAFV60
Externí odkaz:
https://doaj.org/article/5d4d7a8e57754e16812b1b989f4ffe66
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b01d9d85a526473fad40622c3a74faba
Autor:
Lingzhi Hong, Muhammad Aminu, Shenduo Li, Xuetao Lu, Milena Petranovic, Maliazurina B. Saad, Pingjun Chen, Kang Qin, Susan Varghese, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Amy Spelman, Yasir Y. Elamin, Marcelo V. Negrao, Ferdinandos Skoulidis, Carl M. Gay, Tina Cascone, Saumil J. Gandhi, Steven H. Lin, Percy P. Lee, Brett W. Carter, Carol C. Wu, Mara B. Antonoff, Boris Sepesi, Jeff Lewis, Don L. Gibbons, Ara A. Vaporciyan, Xiuning Le, J. Jack Lee, Sinchita Roy-Chowdhuri, Mark J. Routbort, Justin F. Gainor, John V. Heymach, Yanyan Lou, Jia Wu, Jianjun Zhang, Natalie I. Vokes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Immune checkpoint inhibitors with or without chemotherapy are now standard of care for non-small cell lung cancer. However, the benefits of combination vs sequential therapy have not been fully explored. Here, the authors analysed 1,133 patient recor
Externí odkaz:
https://doaj.org/article/8e4eb1b2cf4847c68859d771395453bd
Autor:
Marcelo V. Negrao, MD, Vassiliki A. Papadimitrakopoulou, MD, Andrew C. Price, MD, PhD, Alda L. Tam, MD, MBA, Muhammad Furqan, MD, Sandeep T. Laroia, MD, Erminia Massarelli, MS, MD, PhD, Jose Pacheco, MD, John V. Heymach, MD, PhD, Anne S. Tsao, MD, Gary V. Walker, MD, Lalit Vora, MD, David Mauro, MD, PhD, Heather Kelley, MA, James E. Wooldridge, MD, Arthur M. Krieg, MD, Jiaxin Niu, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 3, Pp 100423- (2023)
Introduction: Vidutolimod, a CpG-A TLR9 agonist, was investigated in a phase 1b study (CMP-001-003; ClinicalTrials.gov, NCT03438318) in combination with atezolizumab with and without radiation therapy (RT) in patients with advanced NSCLC. Methods: Pa
Externí odkaz:
https://doaj.org/article/375520c714da4dd0a0459208063f6fc7
Autor:
Ming Tang, Hussein A. Abbas, Marcelo V. Negrao, Maheshwari Ramineni, Xin Hu, Shawna Marie Hubert, Junya Fujimoto, Alexandre Reuben, Susan Varghese, Jianhua Zhang, Jun Li, Chi-Wan Chow, Xizeng Mao, Xingzhi Song, Won-Chul Lee, Jia Wu, Latasha Little, Curtis Gumbs, Carmen Behrens, Cesar Moran, Annikka Weissferdt, J. Jack Lee, Boris Sepesi, Stephen Swisher, Chao Cheng, Jonathan Kurie, Don Gibbons, John V. Heymach, Ignacio I. Wistuba, P. Andrew Futreal, Neda Kalhor, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The molecular determinants of lung cancer histologic subtypes are not well understood. Here the authors analyze lung cancers of mixed histology and find that histologic subtypes are associated with transcriptomic features rather than genomic profiles
Externí odkaz:
https://doaj.org/article/720ce36826a3427ebaed0bfc5a64e401
Autor:
Won-Chul Lee, Alexandre Reuben, Xin Hu, Nicholas McGranahan, Runzhe Chen, Ali Jalali, Marcelo V. Negrao, Shawna M. Hubert, Chad Tang, Chia-Chin Wu, Anthony San Lucas, Whijae Roh, Kenichi Suda, Jihye Kim, Aik-Choon Tan, David H. Peng, Wei Lu, Ximing Tang, Chi-Wan Chow, Junya Fujimoto, Carmen Behrens, Neda Kalhor, Kazutaka Fukumura, Marcus Coyle, Rebecca Thornton, Curtis Gumbs, Jun Li, Chang-Jiun Wu, Latasha Little, Emily Roarty, Xingzhi Song, J. Jack Lee, Erik P. Sulman, Ganesh Rao, Stephen Swisher, Lixia Diao, Jing Wang, John V. Heymach, Jason T. Huse, Paul Scheet, Ignacio I. Wistuba, Don L. Gibbons, P. Andrew Futreal, Jianhua Zhang, Daniel Gomez, Jianjun Zhang
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background Metastasis is the primary cause of cancer mortality accounting for 90% of cancer deaths. Our understanding of the molecular mechanisms driving metastasis is rudimentary. Results We perform whole exome sequencing (WES), RNA sequenc
Externí odkaz:
https://doaj.org/article/c29b76fbdc184076acd46b769c6e95c6
Autor:
Tassia S. R. da Costa, Ursula Urias, Marcelo V. Negrao, Camila P. Jordão, Clévia S. Passos, Igor L. Gomes‐Santos, Vera Maria C. Salemi, Anamaria A. Camargo, Patricia C. Brum, Edilamar M. Oliveira, Ludhmila A. Hajjar, Roger Chammas, Roberto K. Filho, Carlos E. Negrao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Background Patients treated for breast cancer have a high incidence of cardiovascular complications. In this study, we evaluated the impact of breast cancer on cardiac function and cardiomyocyte Ca2+‐handling protein expression. We also investigate
Externí odkaz:
https://doaj.org/article/be2bbc7f046e46d99d39ba8c807b345d