Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Marcelo T. Bozza"'
Autor:
Elena Montes-Cobos, Victoria C. Bastos, Clarice Monteiro, João C.R. de Freitas, Heiny D.P. Fernandes, Clarice S. Constancio, Danielle A.S. Rodrigues, Andreza M.D.S. Gama, Vinicius M. Vidal, Leticia S. Alves, Laura Zalcberg-Renault, Guilherme S. de Lira, Victor A. Ota, Carolina Caloba, Luciana Conde, Isabela C. Leitão, Amilcar Tanuri, Orlando D.C. Ferreira, Renata M. Pereira, André M. Vale, Terezinha M. Castiñeiras, Dominique Kaiserlian, Juliana Echevarria-Lima, Marcelo T. Bozza
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107219- (2023)
Summary: The vast spectrum of clinical features of COVID-19 keeps challenging scientists and clinicians. Low resistance to infection might result in long-term viral persistence, but the underlying mechanisms remain unclear. Here, we studied the immun
Externí odkaz:
https://doaj.org/article/3fbe702109ad4297862b695b0d6f52bc
Autor:
Gustavo Monnerat, Micaela L. Alarcón, Luiz R. Vasconcellos, Camila Hochman-Mendez, Guilherme Brasil, Rosana A. Bassani, Oscar Casis, Daniela Malan, Leonardo H. Travassos, Marisa Sepúlveda, Juan Ignacio Burgos, Martin Vila-Petroff, Fabiano F. Dutra, Marcelo T. Bozza, Claudia N. Paiva, Adriana Bastos Carvalho, Adriana Bonomo, Bernd K. Fleischmann, Antonio Carlos Campos de Carvalho, Emiliano Medei
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/a2e0e508ba484f888703530cef72d553
Autor:
Marcelo T. Bozza, Viktória Jeney
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Damage associated molecular patterns (DAMPs) are endogenous molecules originate from damaged cells and tissues with the ability to trigger and/or modify innate immune responses. Upon hemolysis hemoglobin (Hb) is released from red blood cells (RBCs) t
Externí odkaz:
https://doaj.org/article/0782d320b8014bcb8381bc99702d7c3c
Autor:
Carolina G. O. Lucas, Jamil Z. Kitoko, Fabricio M. Ferreira, Vinicius G. Suzart, Michelle P. Papa, Sharton V. A. Coelho, Cecilia B. Cavazzoni, Heitor A. Paula-Neto, Priscilla C. Olsen, Akiko Iwasaki, Renata M. Pereira, Pedro M. Pimentel-Coelho, Andre M. Vale, Luciana B. de Arruda, Marcelo T. Bozza
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Characterization of protective immunity to Zika virus has largely focussed on CD8+ T cells and antibody-mediated protection. Here the authors show roles for CD4+ T cells and the associated IFNγ signaling in antibody-mediated resistance to Zika virus
Externí odkaz:
https://doaj.org/article/f7026cc58b4043d2934f510dfe446fd8
Autor:
Gustavo Monnerat, Micaela L. Alarcón, Luiz R. Vasconcellos, Camila Hochman-Mendez, Guilherme Brasil, Rosana A. Bassani, Oscar Casis, Daniela Malan, Leonardo H. Travassos, Marisa Sepúlveda, Juan Ignacio Burgos, Martin Vila-Petroff, Fabiano F. Dutra, Marcelo T. Bozza, Claudia N. Paiva, Adriana Bastos Carvalho, Adriana Bonomo, Bernd K. Fleischmann, Antonio Carlos Campos de Carvalho, Emiliano Medei
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Ventricular arrhythmia is a leading cause of death in patients with diabetes. Here the authors show that inflammasome activation and ILK-1β production in cardiac macrophages cause arrhythmia in diabetic mice, which can be successfully treated using
Externí odkaz:
https://doaj.org/article/dd521bbbf78046d888ba049b54d46e2e
Autor:
Laiana A. Barbosa, Paloma P. Fiuza, Letícia J. Borges, Fellipe A. Rolim, Mayara B. Andrade, Nivea F. Luz, Graziele Quintela-Carvalho, Jonilson B. Lima, Roque P. Almeida, Francis K. Chan, Marcelo T. Bozza, Valeria M. Borges, Deboraci B. Prates
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Necroptosis is a pro-inflammatory cell death, which happens in the context of caspase-8 inhibition, allowing activation of the receptor interacting protein kinase 1–receptor interacting protein kinase 3–mixed lineage kinase domain-like (RIPK1–R
Externí odkaz:
https://doaj.org/article/a44c02c144824bacb91bff7df2bf1930
Autor:
Michelle P. Papa, Lana M. Meuren, Sharton V. A. Coelho, Carolina G. de Oliveira Lucas, Yasmin M. Mustafá, Flavio Lemos Matassoli, Paola P. Silveira, Paula S. Frost, Paula Pezzuto, Milene R. Ribeiro, Amilcar Tanuri, Mauricio L. Nogueira, Loraine Campanati, Marcelo T. Bozza, Heitor A. Paula Neto, Pedro M. Pimentel-Coelho, Claudia P. Figueiredo, Renato S. de Aguiar, Luciana B. de Arruda
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Zika virus (ZIKV) has been associated to central nervous system (CNS) harm, and virus was detected in the brain and cerebrospinal fluids of microcephaly and meningoencephalitis cases. However, the mechanism by which the virus reaches the CNS is uncle
Externí odkaz:
https://doaj.org/article/a7bf18c33a754b9189d2f87ed6c92534
Autor:
Graziele Quintela-Carvalho, Nívea F. Luz, Fabiana S. Celes, Dalila L. Zanette, Daniela Andrade, Diego Menezes, Natália M. Tavares, Claudia I. Brodskyn, Deboraci B. Prates, Marilda S. Gonçalves, Camila I. de Oliveira, Roque P. Almeida, Marcelo T. Bozza, Bruno B. Andrade, Valeria M. Borges
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Free heme is an inflammatory molecule capable of inducing migration and activation of neutrophils. Here, we examine the heme-driven oxidative stress-associated cell death mechanisms in human neutrophils infected with Leishmania infantum, an etiologic
Externí odkaz:
https://doaj.org/article/f915a022ded648099dc2b47672ee661d
Autor:
Carla da S. Pinheiro, Ana Paula T. Monteiro, Fabiano F. Dutra, Marcelo T. Bozza, Marc Peters-Golden, Claudia F. Benjamim, Claudio Canetti
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
TLRs recognize a broad spectrum of microorganism molecules, triggering a variety of cellular responses. Among them, phagocytosis is a critical process for host defense. Leukotrienes (LTs), lipid mediators produced from 5-lipoxygenase (5-LO) enzyme, i
Externí odkaz:
https://doaj.org/article/97d92a8d28ed4d9486dd9c3e955821f5
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Externí odkaz:
https://doaj.org/article/e2421aa57ea9418ea2dcdc30184b3ea0