Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Marcelo T Bozza"'
Autor:
Danielle A S Rodrigues, Elisa B Prestes, Andreza M S Gama, Leandro de Souza Silva, Ana Acácia S Pinheiro, Jose Marcos C Ribeiro, Raquel M P Campos, Pedro M Pimentel-Coelho, Heitor S De Souza, Alassane Dicko, Patrick E Duffy, Michal Fried, Ivo M B Francischetti, Elvira M Saraiva, Heitor A Paula-Neto, Marcelo T Bozza
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008230 (2020)
Neutrophil extracellular traps (NETs) evolved as a unique effector mechanism contributing to resistance against infection that can also promote tissue damage in inflammatory conditions. Malaria infection can trigger NET release, but the mechanisms an
Externí odkaz:
https://doaj.org/article/8894109b3a9d47bbb335252e5084efbe
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008599 (2020)
Heme oxygenase (HO-1) mediates the enzymatic cleavage of heme, a molecule with proinflammatory and prooxidant properties. HO-1 activity deeply impacts host capacity to tolerate infection through reduction of tissue damage or affecting resistance, the
Externí odkaz:
https://doaj.org/article/2f67b0e899bf46d395aba59485e4c767
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006928 (2018)
The activation of macrophage respiratory burst in response to infection with Trypanosoma cruzi inflicts oxidative damage to the host's tissues. For decades, the role of reactive oxygen species (ROS) in the elimination of T. cruzi was taken for grante
Externí odkaz:
https://doaj.org/article/95f023cfbf6f46b28dd1ffa9ddc17926
Autor:
Glaucia Vilar-Pereira, Vitor C Carneiro, Hilton Mata-Santos, Amanda R R Vicentino, Isalira P Ramos, Naira L L Giarola, Daniel F Feijó, José R Meyer-Fernandes, Heitor A Paula-Neto, Emiliano Medei, Marcelo T Bozza, Joseli Lannes-Vieira, Claudia N Paiva
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005947 (2016)
Chronic chagasic cardiomyopathy (CCC) develops years after acute infection by Trypanosoma cruzi and does not improve after trypanocidal therapy, despite reduction of parasite burden. During disease, the heart undergoes oxidative stress, a potential c
Externí odkaz:
https://doaj.org/article/620113a7b3334c11a095afab687e175b
Autor:
Raphael Molinaro, Cyntia Pecli, Rafael F Guilherme, José Carlos Alves-Filho, Fernando Q Cunha, Claudio Canetti, Steven L Kunkel, Marcelo T Bozza, Claudia F Benjamim
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133227 (2015)
Sepsis is a deadly disease characterized by an overwhelming release of inflammatory mediators and the activation of different types of cells. This altered state of cell activation, termed leukocyte reprogramming, contributes to patient outcome. Howev
Externí odkaz:
https://doaj.org/article/f1aa95f233474d98b5617e59b2d51334
Autor:
Marta G Cavalcanti, Jacilene S Mesquita, Kalil Madi, Daniel F Feijó, Iranaia Assunção-Miranda, Heitor S P Souza, Marcelo T Bozza
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25259 (2011)
BACKGROUND: Macrophage migration inhibitory factor (MIF) is essential for controlling parasite burden and survival in a model of systemic Toxoplasma gondii infection. Peroral T. gondii infection induces small intestine necrosis and death in susceptib
Externí odkaz:
https://doaj.org/article/480b0cbaba724360902d5b481deb7b78
Autor:
Elena Montes-Cobos, Victoria C. Bastos, Clarice Monteiro, João C.R. de Freitas, Heiny D.P. Fernandes, Clarice S. Constancio, Danielle A.S. Rodrigues, Andreza M.D.S. Gama, Vinicius M. Vidal, Leticia S. Alves, Laura Zalcberg-Renault, Guilherme S. de Lira, Victor A. Ota, Carolina Caloba, Luciana Conde, Isabela C. Leitão, Amilcar Tanuri, Orlando D.C. Ferreira, Renata M. Pereira, André M. Vale, Terezinha M. Castiñeiras, Dominique Kaiserlian, Juliana Echevarria-Lima, Marcelo T. Bozza
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107219- (2023)
Summary: The vast spectrum of clinical features of COVID-19 keeps challenging scientists and clinicians. Low resistance to infection might result in long-term viral persistence, but the underlying mechanisms remain unclear. Here, we studied the immun
Externí odkaz:
https://doaj.org/article/3fbe702109ad4297862b695b0d6f52bc
Autor:
Leticia Lintomen, Luciana M. Kluppel, Jamil Z. Kitoko, Elena Montes‐Cobos, Vinícius M. Vidal, Luis B. Tan, José Nazioberto de Farias, Heitor S. de Souza, Priscilla C. Olsen, Marcelo T. Bozza
Publikováno v:
European Journal of Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b37f02c15df68d9a9ac6dfad0c4c4d9b
https://doi.org/10.1002/eji.202250016
https://doi.org/10.1002/eji.202250016
Autor:
null Leticia Lintomen, null Luciana M. Kluppel, null Jamil Z. Kitoko, null Elena Montes‐Cobos, null Vinícius Mendes Vidal, null Luis Batista Tan, null José Nazioberto de Farias, null Heitor S. de Souza, null Priscilla C. Olsen, null Marcelo T. Bozza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5060d586108da458ea1158287485ab2
https://doi.org/10.1002/eji.202250016/v3/response1
https://doi.org/10.1002/eji.202250016/v3/response1
Autor:
Elena Montes-Cobos, Victoria C Bastos, Clarice Monteiro, João CR de Freitas, Heiny DP Fernandes, Clarice S Constancio, Danielle AS Rodrigues, Andreza MDS Gama, Vinicius M Vidal, Leticia S Alves, Laura Zalcberg-Renault, Guilherme S de Lira, Victor A Ota, Carolina Caloba, Luciana Conde, Isabela C Leitão, Amilcar Tanuri, Orlando DC Ferreira, Renata M Pereira, André M Vale, Terezinha M Castiñeiras, Dominique Kaiserlian, Juliana Echevarria-Lima, Marcelo T Bozza
SummaryThe vast spectrum of clinical features of COVID-19 keeps challenging scientists and clinicians. Control of pathogen load (host resistance) and prevention of tissue damage (disease tolerance) are essential for the outcome of infectious diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e42575fc1266b8128dc29b1183400976
https://doi.org/10.1101/2022.11.19.22282546
https://doi.org/10.1101/2022.11.19.22282546