Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marcelo S. F. Pereira"'
Autor:
Marcelo S. F. Pereira, Kinnari Sorathia, Yasemin Sezgin, Aarohi Thakkar, Colin Maguire, Patrick L. Collins, Bethany L. Mundy-Bosse, Dean A. Lee, Meisam Naeimi Kararoudi
Publikováno v:
Cancers, Vol 15, Iss 3, p 705 (2023)
Loss of cytotoxicity and defective metabolism are linked to glycogen synthase kinase 3 beta (GSK3β) overexpression in natural killer (NK) cells from patients with acute myeloid leukemia or from healthy donors after expansion ex vivo with IL-15. Drug
Externí odkaz:
https://doaj.org/article/70b2ac6e6ddd4d18b3a0c8dfd6e8d8ed
Autor:
Danielle P A Mascarenhas, Daiane M Cerqueira, Marcelo S F Pereira, Fernanda V S Castanheira, Talita D Fernandes, Graziele Z Manin, Larissa D Cunha, Dario S Zamboni
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006502 (2017)
Legionella pneumophila is a Gram-negative, flagellated bacterium that survives in phagocytes and causes Legionnaires' disease. Upon infection of mammalian macrophages, cytosolic flagellin triggers the activation of Naip/NLRC4 inflammasome, which culm
Externí odkaz:
https://doaj.org/article/fe345c0b68d746658de26232888e9bd3
Autor:
Kamilla Swiech, Aline de Sousa Bomfim, Amanda Mizukami, Renata Nacasaki Silvestre, Marcelo S. F. Pereira, Leticia Delfini Vaz, Pablo Diego Moço, Dimas Tadeu Covas, Júlia Teixeira Cottas de Azevedo, Mario Soares de Abreu Neto, Virgínia Picanço-Castro, Kelen C. R. Malmegrim
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Hematology, Transfusion and Cell Therapy
Hematology, Transfusion and Cell Therapy, Vol 42, Iss 2, Pp 150-158 (2020)
Universidade de São Paulo (USP)
instacron:USP
Hematology, Transfusion and Cell Therapy
Hematology, Transfusion and Cell Therapy, Vol 42, Iss 2, Pp 150-158 (2020)
Introduction Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19 + B-cell malignancies in numerous clinical trials. The CAR molecule, which recognizes c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def046d16d6a1ff5b8e3533cb2aafdbb
Publikováno v:
Methods in Molecular Biology ISBN: 9781071601457
Immunotherapy has been showed as a promisor treatment, in special for hematological diseases. Chimeric antigen receptor T cells (CARs) which are showing satisfactory results in early-phase cancer clinical trials can be highlighted. However, preclinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c72e57723080c73b66071abf2e22ded
https://doi.org/10.1007/978-1-0716-0146-4_18
https://doi.org/10.1007/978-1-0716-0146-4_18
Autor:
Graziele Z. Manin, Fernanda V. S. Castanheira, Talita D. Fernandes, Danielle P. A. Mascarenhas, Daiane M. Cerqueira, Larissa D. Cunha, Marcelo S. F. Pereira, Dario S. Zamboni
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 8, p e1006502 (2017)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Pathogens, Vol 13, Iss 8, p e1006502 (2017)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Legionella pneumophila is a Gram-negative, flagellated bacterium that survives in phagocytes and causes Legionnaires’ disease. Upon infection of mammalian macrophages, cytosolic flagellin triggers the activation of Naip/NLRC4 inflammasome, which cu
Publikováno v:
Cellular Microbiology. 15:2006-2019
Summary Legionnaires' disease is an emerging, severe, pneumonia-like illness caused by the Gram-negative intracellular bacteria Legionella pneumophila, which are able to infect and replicate intracellularly in macrophages. Little is known regarding t
Autor:
José C. Alves-Filho, João Santana da Silva, Dario S. Zamboni, Fernando Q. Cunha, Daniele C. Nascimento, Marcelo S. F. Pereira, Claudia F. Benjamim, Fabiane Sônego, Sandra Y. Fukada
Publikováno v:
Critical Care Medicine. 38:1718-1725
To investigate the role of regulatory T cells in the modulation of long-term immune dysfunction during experimental sepsis. It is well established that sepsis predisposes to development of a pronounced immunosuppression. Nevertheless, the mechanisms
Autor:
Larissa D. Cunha, Daiane M. Cerqueira, Alexandre L. N. Silva, Dario S. Zamboni, Marcelo S. F. Pereira
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Gram-negative bacteria from the Legionella genus are intracellular pathogens that cause a severe form of pneumonia called Legionnaires’ disease. The bacteria replicate intracellularly in macrophages, and the restriction of bacterial replication by
Autor:
Dario S. Zamboni, Marcelo S. F. Pereira, Graziele Z. Manin, Danielle P. A. Mascarenhas, Juliana I. Hori
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Legionella pneumophila, the etiological agent of Legionnaires' disease, triggers activation of multiple innate immune pathways that lead to the restriction of bacterial replication in vivo. Despite the critical role for MyD88 in infection clearance,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6c47bd7e97196df2fc8f4b81179c8f
Autor:
Dario S. Zamboni, Catarina V. Horta, Liliana M. Massis, Marcelo S. F. Pereira, Juliana I. Hori, Giuliano Morgantetti
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(12)
Although NLRC4/IPAF activation by flagellin has been extensively investigated, the downstream signaling pathways and the mechanisms responsible for infection clearance remain unclear. In this study, we used mice deficient for the inflammasome compone