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A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
Autor:
Bianca Zingales, Rafael Gomes Aquino Araujo, Margoth Moreno, Jaques Franco, Pedro Henrique Nascimento Aguiar, Solange Lessa Nunes, Marcelo Nunes Silva, Susan Ienne, Carlos Renato Machado, Adeilton Brandão
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 3, Pp 433-444 (2015)
Benznidazole (BZ) is one of the two drugs used for Chagas disease treatment. Nevertheless therapeutic failures of BZ have been reported, which were mostly attributed to variable drug susceptibility among Trypanosoma cruzi strains. ATP-binding cassett
Externí odkaz:
https://doaj.org/article/1ecbe905cd1f4d0b9ab5d59af41f693a