Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Marcelo NOLLMANN"'
Autor:
Xavier Devos, Jean-Bernard Fiche, Marion Bardou, Olivier Messina, Christophe Houbron, Julian Gurgo, Marie Schaeffer, Markus Götz, Thomas Walter, Florian Mueller, Marcelo Nollmann
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Genome-wide ensemble sequencing methods improved our understanding of chromatin organization in eukaryotes but lack the ability to capture single-cell heterogeneity and spatial organization. To overcome these limitations, new imaging-based m
Externí odkaz:
https://doaj.org/article/71e8100ef7ff4548802e158a94de3b06
Autor:
Julian Gurgo, Jean-Charles Walter, Jean-Bernard Fiche, Christophe Houbron, Marie Schaeffer, Giacomo Cavalli, Frédéric Bantignies, Marcelo Nollmann
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114167- (2024)
Summary: Polycomb (Pc) group proteins are transcriptional regulators with key roles in development, cell identity, and differentiation. Pc-bound chromatin regions form repressive domains that interact in 3D to assemble repressive nuclear compartments
Externí odkaz:
https://doaj.org/article/d337c4c7d82044bebbad543660b3205a
Autor:
Olivier Messina, Flavien Raynal, Julian Gurgo, Jean-Bernard Fiche, Vera Pancaldi, Marcelo Nollmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract In mammals, insulators contribute to the regulation of loop extrusion to organize chromatin into topologically associating domains. In Drosophila the role of insulators in 3D genome organization is, however, under current debate. Here, we ad
Externí odkaz:
https://doaj.org/article/c9400de84f8d4385b99fe41237216dec
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Many species, such as fish schools or bird flocks, rely on collective motion to forage, prey, or escape predators. Likewise, Myxococcus xanthus forages and moves collectively to prey and feed on other bacterial species. These activities requ
Externí odkaz:
https://doaj.org/article/3d742cbca5ff4625b47d869c83013d2b
Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Here the authors applied their recently developed multiplexed DNA-FISH Hi-M method to dissect the sources of heterogeneity in topologically associating domain (TAD)-like organization during Drosophila embryogenesis. This single-nucleus analysis allow
Externí odkaz:
https://doaj.org/article/5d1563da2a5c418a8556a2816c805081
Autor:
Alexandre Martiniere, Olivier Messina, Christophe Houbron, Franziska Barho, Marcelo NOLLMANN, Marion Bardou, Jean-Bernard Fiche
Publikováno v:
Open Research Europe, Vol 2 (2022)
Multiplexed sequential and combinatorial imaging enables the simultaneous detection of multiple biological molecules, e.g. proteins, DNA, or RNA, enabling single-cell spatial multi-omics measurements at sub-cellular resolution. Recently, we designed
Externí odkaz:
https://doaj.org/article/702c870faae746e6bdf45c6ef37809ed
Autor:
Diego I. Cattoni, Andrés M. Cardozo Gizzi, Mariya Georgieva, Marco Di Stefano, Alessandro Valeri, Delphine Chamousset, Christophe Houbron, Stephanie Déjardin, Jean-Bernard Fiche, Inma González, Jia-Ming Chang, Thomas Sexton, Marc A. Marti-Renom, Frédéric Bantignies, Giacomo Cavalli, Marcelo Nollmann
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Eukaryotic genomes are partitioned into self-interacting modules or topologically associated domains (TADs) that exist at the kilo-megabase scale. Here Cattoni et al. combine super-resolution microscopy with DNA-labeling methods to quantify absolute
Externí odkaz:
https://doaj.org/article/e60cd11935584fd2817e693003fc822f
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Multifocus microscopy (MFM) allows sensitive and fast three-dimensional imaging. It relies on the efficient design of diffraction phase gratings yielding homogeneous intensities in desired diffraction orders. Such performances are however gu
Externí odkaz:
https://doaj.org/article/a1264e73eae546be85f0b386585d040d
Autor:
Antoine Le Gall, Diego I. Cattoni, Baptiste Guilhas, Céline Mathieu-Demazière, Laura Oudjedi, Jean-Bernard Fiche, Jérôme Rech, Sara Abrahamsson, Heath Murray, Jean-Yves Bouet, Marcelo Nollmann
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
In most bacteria and archaea, a broadly conserved mitotic-like apparatus assures the inheritance of duplicated genetic material before cell division. Here, the authors use super-resolution microscopies to dissect the activities required for proper DN
Externí odkaz:
https://doaj.org/article/1825329c79334b0d992b8ce95eb77702
Autor:
Salim T. Islam, Nicolas Y. Jolivet, Clémence Cuzin, Akeisha M. Belgrave, Laetitia My, Betty Fleuchot, Laura M. Faure, Utkarsha Mahanta, Ahmad A. Kezzo, Fares Saïdi, Gaurav Sharma, Jean-Bernard Fiche, Benjamin P. Bratton, Julien Herrou, Marcelo Nollmann, Joshua W. Shaevitz, Eric Durand, Tâm Mignot
Publikováno v:
Science Advances
Science Advances, 2023, 9 (8), ⟨10.1126/sciadv.abq0619⟩
Science Advances, 2023, 9 (8), ⟨10.1126/sciadv.abq0619⟩
The predatory deltaproteobacterium Myxococcus xanthus uses a helically-trafficked motor at bacterial focal-adhesion (bFA) sites to power gliding motility. Using total internal reflection fluorescence and force microscopies, we identify the von Willeb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7eaebfac0bf0217c771334d370a36b
https://doi.org/10.1126/sciadv.abq0619
https://doi.org/10.1126/sciadv.abq0619