Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Marcelo G, Bonini"'
Autor:
Flavio R. Palma, Diego R. Coelho, Kirthi Pulakanti, Marcelo J. Sakiyama, Yunping Huang, Fernando T. Ogata, Jeanne M. Danes, Alison Meyer, Cristina M. Furdui, Douglas R. Spitz, Ana P. Gomes, Benjamin N. Gantner, Sridhar Rao, Vadim Backman, Marcelo G. Bonini
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114415- (2024)
Externí odkaz:
https://doaj.org/article/425e2d4d57dd43c7b3fb3e7ae2f1fbd1
Autor:
Diego R. Coelho, Flavio R. Palma, Veronica Paviani, Katy M. LaFond, Yunping Huang, Dongmei Wang, Brian Wray, Sridhar Rao, Feng Yue, Marcelo G. Bonini, Benjamin N. Gantner
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106442- (2023)
Summary: Suppressor of cytokine signaling-1 (SOCS1) exerts control over inflammation by targeting p65 nuclear factor-κB (NF-κB) for degradation in addition to its canonical role regulating cytokine signaling. We report here that SOCS1 does not oper
Externí odkaz:
https://doaj.org/article/2821d6593e51454391f26f5e18f47db1
Autor:
Ying Jiang, Sarah Krantz, Xiang Qin, Shun Li, Hirushi Gunasekara, Young-Mee Kim, Adriana Zimnicka, Misuk Bae, Ke Ma, Peter T. Toth, Ying Hu, Ayesha N. Shajahan-Haq, Hemal H. Patel, Saverio Gentile, Marcelo G. Bonini, Jalees Rehman, Yiyao Liu, Richard D. Minshall
Publikováno v:
Redox Biology, Vol 52, Iss , Pp 102304- (2022)
As essential regulators of mitochondrial quality control, mitochondrial dynamics and mitophagy play key roles in maintenance of metabolic health and cellular homeostasis. Here we show that knockdown of the membrane-inserted scaffolding and structural
Externí odkaz:
https://doaj.org/article/5ff54eba886243c59a38ab64bfa4363d
Autor:
Megan A. Morrell, Tabitha R. Willis, Denisha R. Brown, Catherine A. O’Brian, Sharon L. Post, Gayle E. Woloschak, Marcelo G. Bonini, Tatjana Paunesku, Jelena Popovic, Tarneka M. Manning, Candace Henley, Jorge Girotti, Rosemarie Rogers, Carmen Velásquez, José López, Joanne Glenn, Melissa A. Simon
Publikováno v:
Cancer Causes & Control. 34:621-624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6d219f52c0fc10d2224c890fdc6408c
https://doi.org/10.1007/s10552-023-01699-7
https://doi.org/10.1007/s10552-023-01699-7
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101550- (2020)
Nitric oxide synthases are the major sources of nitric oxide, a critical signaling molecule involved in a wide range of cellular and physiological processes. These enzymes comprise a family of genes that are highly conserved across all eukaryotes. Th
Externí odkaz:
https://doaj.org/article/939bbf09819043c2aa88fd21f76a3ef2
Autor:
Diego R. Coelho, Flavio R. Palma, Veronica Paviani, Chenxia He, Jeanne M. Danes, Yunping Huang, Juliana C. P. Calado, Peter C. Hart, Cristina M. Furdui, Leslie B. Poole, Matthew J. Schipma, Marcelo G. Bonini
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
The dichotomous behavior of superoxide dismutase-2 (SOD2) in cancer biology has long been acknowledged and more recently linked to different posttranslational forms of the enzyme. However, a distinctive activity underlying its tumor-promoting functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41188f3baa7f104b3b6b6bd58db9f0c9
https://pubmed.ncbi.nlm.nih.gov/35858297
https://pubmed.ncbi.nlm.nih.gov/35858297
Autor:
Flavio R. Palma, Fernando T. Ogata, Diego R. Coelho, Kirthi Pulakanti, Alison Meyer, Yunping Huang, Jeanne M. Danes, Matthew J. Schipma, Cristina M. Furdui, Douglas R. Spitz, Benjamin N. Gantner, Sridhar Rao, Vadim Backman, Marcelo G. Bonini
Transcription stability enforces cellular identity and is tightly controlled by restrictions imposed on both transcription factor function and target gene accessibility. Progression of cancer to metastasis and multi-drug resistance requires fluid tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a8fa83fdfc2ea197f8e80401389d93
https://doi.org/10.1101/2022.12.01.517361
https://doi.org/10.1101/2022.12.01.517361
Autor:
Lakshmi R. Bollu, Prashant V. Bommi, Paige J. Monsen, Lijie Zhai, Kristen L. Lauing, April Bell, Miri Kim, Erik Ladomersky, Xinyu Yang, Leonidas C. Platanias, Daniela E. Matei, Marcelo G. Bonini, Hidayatullah G. Munshi, Rintaro Hashizume, Jennifer D. Wu, Bin Zhang, Charles David James, Peiwen Chen, Masha Kocherginsky, Craig Horbinski, Michael D. Cameron, Arabela A. Grigorescu, Bakhtiar Yamini, Rimas V. Lukas, Gary E. Schiltz, Derek A. Wainwright
Publikováno v:
Journal of medicinal chemistry. 65(23)
Indoleamine 2,3-dioxygenase 1 (IDO1) is a potent immunosuppressive enzyme that inhibits the antitumor immune response through both tryptophan metabolism and non-enzymatic functions. To date, most IDO1-targeted approaches have focused on inhibiting tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1056cfbddd37cd845aa59f9b40770418
https://pubmed.ncbi.nlm.nih.gov/36410047
https://pubmed.ncbi.nlm.nih.gov/36410047
Autor:
Benjamin N. Gantner, Marcelo G. Bonini, Diego R. Coelho, Chenxia He, Jeanne M. Danes, Veronica Paviani, Flavio R. Palma
Publikováno v:
Antioxid Redox Signal
Significance: Reactive oxygen species (ROS) are now widely recognized as central mediators of cell signaling. Mitochondria are major sources of ROS. Recent Advances: It is now clear that mitochondrial ROS are essential to activate responses to cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd59f0bc511886e77569ac7517c84fc
https://doi.org/10.1089/ars.2019.7962
https://doi.org/10.1089/ars.2019.7962
Autor:
Lakshmi Bollu, Prashant V. Bommi, Paige J. Monsen, Lijie Zhai, Kristen L. Lauing, April Bell, Miri Kim, Erik Ladomersky, Leonidas C. Platanias, Daniela E. Matei, Marcelo G. Bonini, Hidayatullah G. Munshi, Rintaro Hashizume, Jennifer D. Wu, Bin Zhang, C. David James, Peiwen Chen, Masha Kocherginsky, Craig Horbinski, Michael D. Cameron, Arabela A. Grigorescu, Bakhtiar Yamini, Rimas V. Lukas, Gary E. Schiltz, Derek Alan Wainwright
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3047897b4e9019e4fdeb869d06cf646
https://doi.org/10.2139/ssrn.4081515
https://doi.org/10.2139/ssrn.4081515