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Autor:
Baoan Ji, Patrick Hwu, James L. Abbruzzese, David Z. Chang, Kuichun Zhu, Laszlo Radvanyi, Pedro Cano, Gregory Lizée, Marcelo Fernando-Vina
Publikováno v:
Cancer Immunology, Immunotherapy. 56:719-724
Pancreatic cancer is being pursued as an immunotherapy target using antigen-specific vaccine approaches activating CD8(+) CTL and CD4(+) T-helper cells. CD8(+) CTL exert their anti-tumor effects in an HLA-restricted manner and only tumor cells carryi