Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Marcelo F. Santiago"'
Autor:
Louise A. Mesentier-Louro, Leandro C. Teixeira-Pinheiro, Fernanda Gubert, Juliana F. Vasques, Almir J. Silva-Junior, Luiza Chimeli-Ormonde, Gabriel Nascimento-dos-Santos, Rosalia Mendez-Otero, Marcelo F. Santiago
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2019)
Abstract Background Retina and/or optic nerve injury may cause irreversible blindness, due to degeneration of retinal ganglion cells. We and others have previously shown that the intravitreal injection of mesenchymal stem cells (MSCs) protects injure
Externí odkaz:
https://doaj.org/article/bdc70fc946864252af28a6c75881ea32
Autor:
João F. Gomes-Neto, Rossella Sartorius, Fábio B. Canto, Thamyres S. Almeida, André A. Dias, Carlos-Henrique D. Barbosa, Guilherme A. Melo, Ana Carolina Oliveira, Pedro-Henrique N. Aguiar, Carlos R. Machado, Herbert L. de Matos Guedes, Marcelo F. Santiago, Alberto Nóbrega, Piergiuseppe De Berardinis, Maria Bellio
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Recombinant filamentous fd bacteriophages (rfd) expressing antigenic peptides were shown to induce cell-mediated immune responses in the absence of added adjuvant, being a promising delivery system for vaccination. Here, we tested the capacity of rfd
Externí odkaz:
https://doaj.org/article/c78c4a8f486d4d99930c762236a7c01a
Autor:
Ronaldo Mohana-Borges, Juliana Ferreira Vasques, Fernanda Gubert, Rafael Lani-Louzada, Rosalia Mendez-Otero, Carla Andreia Abreu, Marcelo F. Santiago, Almir Jordão da Silva-Junior, Leandro Coelho Teixeira-Pinheiro, Gabriel Nascimento-dos-Santos, Eduardo de Souza Matos, Pedro M. Pimentel-Coelho
Publikováno v:
Journal of Neurochemistry. 158:694-709
Gangliosides are glycosphingolipids abundantly expressed in the vertebrate nervous system, and are classified in a-, b-, or c- series according to the number of sialic-acid residues. The enzyme GD3 synthase converts GM3 (an a- series ganglioside) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e69884e2acb838492a864ff56a7a581
https://doi.org/10.1111/jnc.15443
https://doi.org/10.1111/jnc.15443
Autor:
Fernanda Gubert, Camila Zaverucha-do-Valle, Michelle Furtado, Pedro M. Pimentel-Coelho, Nicoli Mortari, Ana C. M. Leão, Elize A. Hayashi, Alberto Nobrega, Rosalia Mendez-Otero, Marcelo F. Santiago
Publikováno v:
Stem Cells International, Vol 2017 (2017)
CD60b antigens are highly expressed during development in the rat nervous system, while in the adult their expression is restricted to a few regions, including the subventricular zone (SVZ) around the lateral ventricles—a neurogenic niche in the ad
Externí odkaz:
https://doaj.org/article/d3a714f4f9834e10b415c72359caca23
Autor:
Louise A. Mesentier-Louro, Camila Zaverucha-do-Valle, Paulo H. Rosado-de-Castro, Almir J. Silva-Junior, Pedro M. Pimentel-Coelho, Rosalia Mendez-Otero, Marcelo F. Santiago
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Following optic nerve injury associated with acute or progressive diseases, retinal ganglion cells (RGCs) of adult mammals degenerate and undergo apoptosis. These diseases have limited therapeutic options, due to the low inherent capacity of RGCs to
Externí odkaz:
https://doaj.org/article/035ad40ece1d45e1b56822c3623e56f8
Congenital toxoplasmosis constitutes a major cause of pre- and post-natal complications. Fetal infection with Toxoplasma gondii influences development and can lead to microcephaly, encephalitis, and neurological abnormalities. Few studies have attemp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b25b29a1507cd4318bb340af7e54c65a
https://doi.org/10.1101/2021.05.31.446482
https://doi.org/10.1101/2021.05.31.446482
Autor:
Marcelo F. Santiago, Luiza Rachel Pinheiro de Carvalho, William W. Hauswirth, Hilda Petrs-Silva, Leandro Coelho Teixeira-Pinheiro, Rosalia Mendez-Otero, Almir Jordão da Silva-Junior, Gabriel Nascimento-dos-Santos, Louise A. Mesentier-Louro
Publikováno v:
Gene Therapy. 27:27-39
After an injury, axons in the central nervous system do not regenerate over large distances and permanently lose their connections to the brain. Two promising approaches to correct this condition are cell and gene therapies. In the present work, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e36b1783b30af3f4700c5b17202484a
https://doi.org/10.1038/s41434-019-0089-0
https://doi.org/10.1038/s41434-019-0089-0
Autor:
Louise Alessandra Mesentier-Louro, Camila Zaverucha-do-Valle, Almir Jordão da Silva-Junior, Gabriel Nascimento-Dos-Santos, Fernanda Gubert, Ana Beatriz Padilha de Figueirêdo, Ana Luiza Torres, Bruno D Paredes, Camila Teixeira, Fernanda Tovar-Moll, Rosalia Mendez-Otero, Marcelo F Santiago
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110722 (2014)
Bone marrow-derived cells have been used in different animal models of neurological diseases. We investigated the therapeutic potential of mesenchymal stem cells (MSC) injected into the vitreous body in a model of optic nerve injury. Adult (3-5 month
Externí odkaz:
https://doaj.org/article/d0a2457b054940b294eba12c0778ec33
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 73, Iss 2, Pp 221-229 (2001)
Migration of neurons from their site of origin to their final destination is a critical and universal step in the formation of the complex structure of the nervous system. The migratory process is thought to be governed in part by genetically and epi
Externí odkaz:
https://doaj.org/article/48b3e3480bf24affb37457cccd4ad36d
Autor:
Luiza Rachel Pinheiro de Carvalho, Leandro Coelho Teixeira-Pinheiro, Louise A. Mesentier-Louro, Gabriel Nascimento-dos-Santos, Victor Bodart-Santos, Rosalia Mendez-Otero, Marcelo F. Santiago, Luiza Chimeli-Ormonde, Almir Jordão da Silva-Junior, Juliana Ferreira Vasques
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Background Optic-nerve injury results in impaired transmission of visual signals to central targets and leads to the death of retinal ganglion cells (RGCs) and irreversible vision loss. Therapies with mesenchymal stem cells (MSCs) from different sour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987551a396e5998aa57537fef06aea5b
https://doi.org/10.1186/s13287-020-02130-7
https://doi.org/10.1186/s13287-020-02130-7