Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Marcelo Dias Baruffi"'
Autor:
Fernanda P Prado, Daniele O Dos Santos, Valdecir Blefari, Carlos A Silva, Juliano Machado, Isis do Carmo Kettelhut, Simone G Ramos, Marcelo Dias Baruffi, Helio C Salgado, Cibele M Prado
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189469 (2017)
Hypertension causes cardiac hypertrophy, one of the most important risk factors for heart failure (HF). Despite the importance of cardiac hypertrophy as a risk factor for the development of HF, not all hypertrophied hearts will ultimately fail. Alter
Externí odkaz:
https://doaj.org/article/49989d8ff21f4f7d975406a3fe545151
Autor:
Thais F.C. Fraga-Silva, Ualter G. Cipriano, Marcilio J. Fumagalli, Giseli F. Correa, Carlos A. Fuzo, Douglas dos-Santos, Fabiola L.A.C. Mestriner, Christiane Becari, Andrea Teixeira-Carvalho, Jordana Coelho-dos-Reis, Mayra G. Menegueti, Luiz T.M. Figueiredo, Larissa D. Cunha, Olindo A. Martins-Filho, Marcelo Dias-Baruffi, Maria Auxiliadora-Martins, Rita C. Tostes, Vania L.D. Bonato
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108366- (2023)
Summary: Airway epithelial cells (AEC) infected with SARS-CoV-2 may drive the dysfunction of macrophages during COVID-19. We hypothesized that the direct interaction of AEC with macrophages mediated by CD95/CD95L or indirect interaction mediated by I
Externí odkaz:
https://doaj.org/article/0fafe3cabae341cb9ed8ae07f59c750a
Autor:
Sterre L. Siekman, Tamas Pongracz, Wenjun Wang, Jan Nouta, Peter G. Kremsner, Pedro Vieira da Silva-Neto, Meral Esen, Andrea Kreidenweiss, Jana Held, Átila Alexandre Trapé, Rolf Fendel, Isabel Kinney Ferreira de Miranda Santos, Manfred Wuhrer, ImmunoCovid Consortium, Alessandro P. de Amorim, Jamille G M. Argolo, Rita de C.C. Barbieri, Marcelo Dias-Baruffi, Victor A F. Bastos, Vânia L D. Bonat, Cristina Ribeiro de Barros Cardoso, Ingryd Carmona-Garcia, Jonatan C S de Carvalho, Leticia F. Constant, Augusto M. Degiovani, Cassia F.S.L. Dias, Lúcia H. Faccioli, Marley R. Feitosa, Omar Feres, Ana Paula Morais Fernandes, Talita M. Fernandes, Thais F C. Fraga-Silva, Carlos Fuzo, Isabelle C. Guarneri, Cristiane M. Milanezi, Caroline T. Garbato, Gilberto Gambero Gaspar, Ângelo A.F. Júnior, Sandra R. Maruyama, Debora C. Nepomuceno, Nicola T. Neto, Camilla Narjara Simão Oliveira, Fátima M. Ostini, Rogerio S. Parra, Malena M. Pérez, Vinı́cius E. Pimentel, Giovanna da S. Porcel, José J R da Rocha, Lilian C. Rodrigues, Elisa M S. Russo, Dayane P. da Silva, Rafael C. da Silva, Carlos Arterio Sorgi, Camila O S. Souza, Diana M. Toro, Angelina L. Viana, Fernando Crivelenti Vilar, Ana C. Xavier, Kamila Zaparoli
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunoglobulin G (IgG) antibodies play an important role in the immune response against viruses such as SARS-CoV-2. As the effector functions of IgG are modulated by N-glycosylation of the Fc region, the structure and possible function of the IgG N-g
Externí odkaz:
https://doaj.org/article/6158a9fbd2d94ee5a9418faadd9e7247
Autor:
Diana Mota Toro, Pedro V. da Silva-Neto, Jonatan C. S. de Carvalho, Carlos A. Fuzo, Malena M. Pérez, Vinícius E. Pimentel, Thais F. C. Fraga-Silva, Camilla N. S. Oliveira, Glaucia R. Caruso, Adriana F. L. Vilela, Pedro Nobre-Azevedo, Thiago V. Defelippo-Felippe, Jamille G. M. Argolo, Augusto M. Degiovani, Fátima M. Ostini, Marley R. Feitosa, Rogerio S. Parra, Fernando C. Vilar, Gilberto G. Gaspar, José J. R. da Rocha, Omar Feres, Gabriel P. Costa, Sandra R. C. Maruyama, Elisa M. S. Russo, Ana Paula M. Fernandes, Isabel K. F. M. Santos, Adriana Malheiro, Ruxana T. Sadikot, Vânia L. D. Bonato, Cristina R. B. Cardoso, Marcelo Dias-Baruffi, Átila A. Trapé, Lúcia H. Faccioli, Carlos A. Sorgi, ImmunoCovid Consortium Group
Publikováno v:
Cells, Vol 12, Iss 15, p 1938 (2023)
SARS-CoV-2 infection triggers distinct patterns of disease development characterized by significant alterations in host regulatory responses. Severe cases exhibit profound lung inflammation and systemic repercussions. Remarkably, critically ill patie
Externí odkaz:
https://doaj.org/article/08327d39112b4723bd7923540f24fd0a
Autor:
Jonatan C. S. de Carvalho, Pedro V. da Silva-Neto, Diana M. Toro, Carlos A. Fuzo, Viviani Nardini, Vinícius E. Pimentel, Malena M. Pérez, Thais F. C. Fraga-Silva, Camilla N. S. Oliveira, Augusto M. Degiovani, Fátima M. Ostini, Marley R. Feitosa, Rogerio S. Parra, José J. R. da Rocha, Omar Feres, Fernando C. Vilar, Gilberto G. Gaspar, Isabel K. F. M. Santos, Ana P. M. Fernandes, Sandra R. Maruyama, Elisa M. S. Russo, Vânia L. D. Bonato, Cristina R. B. Cardoso, Marcelo Dias-Baruffi, Lúcia H. Faccioli, Carlos A. Sorgi, on behalf of the ImmunoCovid Study Group
Publikováno v:
Viruses, Vol 15, Iss 2, p 573 (2023)
COVID-19 is associated with a dysregulated immune response. Currently, several medicines are licensed for the treatment of this disease. Due to their significant role in inhibiting pro-inflammatory cytokines and lipid mediators, glucocorticoids (GCs)
Externí odkaz:
https://doaj.org/article/8571dd7050f54f5e89a23cd7c0e0bc72
Autor:
Thais Fernanda de Campos Fraga-Silva, Sandra Regina Maruyama, Carlos Arterio Sorgi, Elisa Maria de Sousa Russo, Ana Paula Morais Fernandes, Cristina Ribeiro de Barros Cardoso, Lucia Helena Faccioli, Marcelo Dias-Baruffi, Vânia Luiza Deperon Bonato
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
In the last few months, the coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide and has provoked an exceptional effort from the scientific community to understand the disease. Clinical evidence suggests that severe
Externí odkaz:
https://doaj.org/article/2c54df9216ae42708c1a4c645b7c9340
Autor:
Pedro V. da Silva-Neto, Valéria B. do Valle, Carlos A. Fuzo, Talita M. Fernandes, Diana M. Toro, Thais F. C. Fraga-Silva, Patrícia A. Basile, Jonatan C. S. de Carvalho, Vinícius E. Pimentel, Malena M. Pérez, Camilla N. S. Oliveira, Lilian C. Rodrigues, Victor A. F. Bastos, Sandra O. C. Tella, Ronaldo B. Martins, Augusto M. Degiovani, Fátima M. Ostini, Marley R. Feitosa, Rogerio S. Parra, Fernando C. Vilar, Gilberto G. Gaspar, José J. R. da Rocha, Omar Feres, Eurico Arruda, Sandra R. Maruyama, Elisa M. S. Russo, Angelina L. Viana, Isabel K. F. M. Santos, Vânia L. D. Bonato, Cristina R. B. Cardoso, Jose E. Tanus-Santos, Eduardo A. Donadi, Lucia H. Faccioli, Marcelo Dias-Baruffi, Ana P. M. Fernandes, Raquel F. Gerlach, Carlos A. Sorgi, on behalf of the IMMUNOCOVID Study Group
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 604 (2022)
Patients with COVID-19 predominantly have a respiratory tract infection and acute lung failure is the most severe complication. While the molecular basis of SARS-CoV-2 immunopathology is still unknown, it is well established that lung infection is as
Externí odkaz:
https://doaj.org/article/a4761d57afc64085bf12c2d1efb8f8ed
Autor:
Andréa Queiroz Maranhão, Heidi Muniz Silva, Waldeyr Mendes Cordeiro da Silva, Renato Kaylan Alves França, Thais Canassa De Leo, Marcelo Dias-Baruffi, Rafael Trindade Burtet, Marcelo Macedo Brigido
Publikováno v:
Bioinformatics and Biology Insights, Vol 14 (2020)
Phage display is a powerful technique to select high-affinity antibodies for different purposes, including biopharmaceuticals. Next-generation sequencing (NGS) presented itself as a robust solution, making it possible to assess billions of sequences
Externí odkaz:
https://doaj.org/article/eecb480c55b1442c8b122dce57a5b4d3
Autor:
Pedro V. da Silva-Neto, Jonatan C. S. de Carvalho, Vinícius E. Pimentel, Malena M. Pérez, Diana M. Toro, Thais F. C. Fraga-Silva, Carlos A. Fuzo, Camilla N. S. Oliveira, Lilian C. Rodrigues, Jamille G. M. Argolo, Ingryd Carmona-Garcia, Nicola T. Neto, Camila O. S. Souza, Talita M. Fernandes, Victor A. F. Bastos, Augusto M. Degiovani, Leticia F. Constant, Fátima M. Ostini, Marley R. Feitosa, Rogerio S. Parra, Fernando C. Vilar, Gilberto G. Gaspar, José J. R. da Rocha, Omar Feres, Fabiani G. Frantz, Raquel F. Gerlach, Sandra R. Maruyama, Elisa M. S. Russo, Angelina L. Viana, Ana P. M. Fernandes, Isabel K. F. M. Santos, Vânia L. D. Bonato, Antonio L. Boechat, Adriana Malheiro, Ruxana T. Sadikot, Marcelo Dias-Baruffi, Cristina R. B. Cardoso, Lúcia H. Faccioli, Carlos A. Sorgi, on behalf of the IMUNOCOVID Study Group
Publikováno v:
Viruses, Vol 13, Iss 12, p 2521 (2021)
Uncontrolled inflammatory responses play a critical role in coronavirus disease (COVID-19). In this context, because the triggering-receptor expressed on myeloid cells-1 (TREM-1) is considered an intrinsic amplifier of inflammatory signals, this stud
Externí odkaz:
https://doaj.org/article/11ff9cf45f4e4d15bd09faff571b2561
Autor:
Amanda Larissa Dias Pacheco, Igor Santana de Melo, Maisa de Araujo Costa, Mariah Morais Celestino Amaral, Nívea Karla de Gusmão Taveiros Silva, Yngrid Mickaelli Oliveira Santos, Daniel Leite Góes Gitaí, Marcelo Duzzioni, Alexandre Urban Borbely, Robinson Sabino Silva, Ana Luiza Ferreira Donatti, Luisa Mestriner, Carlos Alessandro Fuzo, Richard D. Cummings, Norberto Garcia-Cairasco, Marcelo Dias-Baruffi, Olagide Wagner de Castro
Publikováno v:
Molecular Neurobiology. 59:7354-7369
Intrahippocampal pilocarpine microinjection (H-PILO) induces status epilepticus (SE) that can lead to spontaneous recurrent seizures (SRS) and neurodegeneration in rodents. Studies using animal models have indicated that lectins mediate a variety of