Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Marcelo D, Gomes"'
Autor:
Lidia M. Yshii, Adriana O. Manfiolli, Alexandre Denadai-Souza, Paula F. Kinoshita, Marcelo D. Gomes, Cristoforo Scavone
Publikováno v:
IBRO Reports, Vol 9, Iss , Pp 218-223 (2020)
Background: Parkinson's disease (PD) is a neurodegenerative disease characterized by intracellular inclusions named Lewy bodies (LB), and alpha-synuclein (asyn) is the major component of these protein aggregates. The precise physiological and patholo
Externí odkaz:
https://doaj.org/article/e53b55c2c57d45049a1108269ee32eb9
Autor:
Alexandre Denadai-Souza, Adriana Oliveira Manfiolli, L. M. Yshii, Marcelo D. Gomes, Paula Fernanda Kinoshita, Cristoforo Scavone
Publikováno v:
IBRO Reports, Vol 9, Iss, Pp 218-223 (2020)
IBRO Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
IBRO Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Highlights • TRAF6 binds to both WT and the mutant form A30 P asyn in SH-SY5Y cell model. • The activation of NF-κB leads to changes in cytokines levels induced by TRAF6 - WT asyn interaction decreasing cell viability. • The interaction betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22abc28f919a4be7871467c2b5d61b34
http://www.sciencedirect.com/science/article/pii/S2451830120300388
http://www.sciencedirect.com/science/article/pii/S2451830120300388
Autor:
Carol Kobori da Fonseca, Marcelo D. Gomes, Raul Alexander Gonzáles-Córdova, Camila Gachet-Castro, Munira Muhammad Abdel Baqui, Felipe Freitas-Castro, Hellen Ishikawa-Ankerhold
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Host manipulation is a common strategy for invading pathogens. Trypanosoma cruzi, the causative agent of Chagas Disease, lives intracellularly within host cells. During infection, parasite-associated modifications occur to the host cell metabolism an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b6f803a0dcfad1818397ff81b03c0e
http://europepmc.org/articles/PMC8560699
http://europepmc.org/articles/PMC8560699
Autor:
Patrícia Maria Siqueira dos Passos, Natália Borges Simaroli, Felipe R. Teixeira, Tycho E. T. Mevissen, Joice S. Oliveira, Marcelo D. Gomes, Heike Laman, Valentine Spagnol, Camila R.S.T.B. de Correia, Suzanne J. Randle, David Komander, Caio Almeida Batista de Oliveira, Ana C. Medeiros
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biochimica et Biophysica Acta. General Subjects
Universidade de São Paulo (USP)
instacron:USP
Biochimica et Biophysica Acta. General Subjects
Background Ubiquitously eXpressed Transcript isoform 2 (UXT—V2) is a prefoldin-like protein involved in NF-κB signaling, apoptosis, and the androgen and estrogen response. UXT-V2 is a cofactor in the NF-κB transcriptional enhanceosome, and its kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f95f5b0ac07eecea9d520eac11761e
https://www.repository.cam.ac.uk/handle/1810/310834
https://www.repository.cam.ac.uk/handle/1810/310834
Autor:
Marcelo D. Gomes, Flávia Alessandra Guarnier, Rosely Oliveira Godinho, Enio Setsuo Arakaki Pacini, Priscila Oliveira Coelho, Livia S. Zaramela, Leonardo Bruno Figueiredo
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Muscle wasting or atrophy is extensively associated with human systemic diseases including diabetes, cancer, and kidney failure. Accumulating evidence from transcriptional profiles has noted that a common set of genes, termed atrogenes, is modulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e485d60d6938ee42d5ef93fc04390d
Autor:
Munira Muhammad Abdel Baqui, Ana C. Medeiros, Priscila Oliveira Coelho, Felipe R. Teixeira, Cláudia Sossai Soares, Nichelle A. Vieira, Marcelo D. Gomes
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
SAMHD1 (Sterile alpha motif and histidine-aspartic acid (HD) domain containing protein 1) is a deoxyribonucleoside triphosphate (dNTP) triphosphohydrolase (dNTPase) that restricts viral replication in infected cells. This protein is also involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f123dc838697ae39fa5e11ce4c81fc8
https://pubmed.ncbi.nlm.nih.gov/29614270
https://pubmed.ncbi.nlm.nih.gov/29614270
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Autophagy is the process of degradation of intracellular proteins through the lysosome. Members of the tripartite motif (TRIM) proteins have shown to directly recognize autophagic cargo and also to act as a hub for the phagophore nucleation complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bd92ade70cb231451ac0ed61dd5757
https://pubmed.ncbi.nlm.nih.gov/29107100
https://pubmed.ncbi.nlm.nih.gov/29107100
Autor:
Felipe R. Teixeira, Nichelle A. Vieira, Marcelo D. Gomes, Priscila Oliveira Coelho, Dimitrius Santiago Guimarães, Ana C. Medeiros, Adriana Oliveira Manfiolli, Deborah Schechtman
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The FBXO25 mediates degradation of ELK-1 and thus inhibits transcriptional activation of immediate early genes (iEG). Here we show that FBXO25 regulates yet another node of this signaling pathway, by decreasing MAPK/ERK activity. We show that inducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a8120819091c565e0dde66a4a6a9df
https://pubmed.ncbi.nlm.nih.gov/28389297
https://pubmed.ncbi.nlm.nih.gov/28389297
Autor:
Rubens Cecchini, Andréia Akemi Suzukawa, Andréa Name Colado Simão, Ana Leticia Maragno, Alessandra Lourenço Cecchini, Marcelo D. Gomes, Flávia Alessandra Guarnier
Publikováno v:
Muscle & Nerve. 42:950-958
Reactive oxygen species oxidize proteins and modulate the proteasomal system in muscle-wasting cancer cachexia. On day 5 (D5), day 10 (D10), and day 14 (D14) after tumor implantation, skeletal muscle was evaluated. Carbonylated proteins and thiobarbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40b96475089c424a5d07e2befc1db3dd
https://doi.org/10.1002/mus.21798
https://doi.org/10.1002/mus.21798
Autor:
Marcelo D. Gomes, Peirang Cao, Christina Gedicke, Monte S. Willis, Lucie Carrier, Stewart H. Lecker, Saskia Schlossarek, Christian C. Witt, Thomas Eschenhagen, Siegfried Labeit, Giulia Mearini, Elisabeth Krämer
Publikováno v:
Cardiovascular Research. 85:357-366
Aims Familial hypertrophic cardiomyopathy (FHC) is frequently caused by cardiac myosin-binding protein C (cMyBP-C) gene mutations, which should result in C-terminal truncated mutants. However, truncated mutants were not detected in myocardial tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356a53008490aa099eaa6de4c90d3825
https://doi.org/10.1093/cvr/cvp348
https://doi.org/10.1093/cvr/cvp348