Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Marcelo A. Fernandez-Viña"'
Autor:
Aleksandr Lazaryan, Tao Wang, Stephen R. Spellman, Hai-Lin Wang, Joseph Pidala, Taiga Nishihori, Medhat Askar, Richard Olsson, Machteld Oudshoorn, Hisham Abdel-Azim, Agnes Yong, Manish Gandhi, Christopher Dandoy, Bipin Savani, Gregory Hale, Kristin Page, Menachem Bitan, Ran Reshef, William Drobyski, Steven GE Marsh, Kirk Schultz, Carlheinz R. Müller, Marcelo A. Fernandez-Viña, Michael R. Verneris, Mary M. Horowitz, Mukta Arora, Daniel J. Weisdorf, Stephanie J. Lee
Publikováno v:
Haematologica, Vol 101, Iss 10 (2016)
The diversity of the human leukocyte antigen (HLA) class I and II alleles can be simplified by consolidating them into fewer supertypes based on functional or predicted structural similarities in epitope-binding grooves of HLA molecules. We studied t
Externí odkaz:
https://doaj.org/article/c1fc847068c24f8d8c8cdd7e167536b7
Autor:
Ming Li, Virginie Rozot, Yvonne R. Thorstenson, Michael N. Mindrinos, Mark M. Davis, Farbod Babrzadeh, Tracy T. Nguyen, Chunlin Wang, Raquel Kuehn, Marcelo A. Fernandez Viña, Thomas J. Scriba, Huang Huang, Sujatha Krishnakumar, Sandeep Kancharla, Marilyn Fukushima, Lisa E. Creary
Publikováno v:
Human Immunology. 79:839-847
The development of next-generation sequencing (NGS) methods for HLA genotyping has already had an impact on the scope and precision of HLA research. In this study, allelic resolution HLA typing was obtained for 402 individuals from Cape Town, South A
Autor:
Hsin-Hsu Wu, Kent P. Jensen, Thomas A. Pham, Philip W. Lavori, John D. Scandling, Marcelo A. Fernandez Viña, Everett Meyer, Jeffrey Waters, Stephan Busque, Kevin Sheehan, Asha Shori, Okmi Choi, Judith A. Shizuru, Robert Lowsky, Richard T. Hoppe, John S. Tamaresis, Samuel Strober, Edgar G. Engleman
Publikováno v:
Sci Transl Med
Preclinical studies have shown that persistent mixed chimerism is linked to acceptance of organ allografts without immunosuppressive (IS) drugs. Mixed chimerism refers to continued mixing of donor and recipient hematopoietic cells in recipient tissue
Autor:
Kriengsak Limkittikul, Danaya Chansinghakule, Aviva Geretz, Philip K. Ehrenberg, Nelson L. Michael, Marcelo A. Fernandez Viña, Alain Bouckenooghe, Rasmi Thomas
Publikováno v:
Human Immunology. 79:773-780
The human leukocyte antigen (HLA) genes are highly variable and are known to play an important role in disease outcomes, including infectious diseases. Prior knowledge of HLA polymorphisms in a population usually forms the basis for an effective case
Autor:
Keith McCullough, Robert M. Merion, Valerie Teal, Marcelo A. Fernandez Viña, Martin Maiers, Hongzhe Li, Alan B. Leichtman, Malek Kamoun
Publikováno v:
Transplantation
Background The association of HLA mismatching with kidney allograft survival has been well established. We examined whether amino acid (AA) mismatches (MMs) at the antigen recognition site of HLA molecules represent independent and incremental risk f
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:S310
Introduction Chimerism testing of peripheral blood and bone marrow aspirates following allogeneic hematopoietic cell transplantation (HCT) is important to evaluate engraftment kinetics and potentially early detection of disease relapse1. NGS-based ch
Autor:
Carlheinz Mueller, Alois Gratwohl, Adetola A. Kassim, Kwang Woo Ahn, Effie W. Petersdorf, Claudio Anasetti, Jason Dehn, Stephanie J. Lee, Hai-Lin Wang, Taiga Nishihori, Jan Storek, Ann E. Woolfrey, Stephen R. Spellman, Mahmoud Aljurf, Wael Saber, Marcelo A. Fernandez Viña, Joseph Pidala, Kirk R. Schultz, Medhat Askar, Vikas Gupta, Rabi Hanna, Mary M. Horowitz, William A. Wood, Yoshihiro Inamoto, Carolyn Katovich Hurley, James Robinson, Vinod K. Prasad, Bronwen E. Shaw, Machteld Oudshoorn
Publikováno v:
Blood. 124:2596-2606
We examined current outcomes of unrelated donor allogeneic hematopoietic cell transplantation (HCT) to determine the clinical implications of donor-recipient HLA matching. Adult and pediatric patients who had first undergone myeloablative-unrelated b
Autor:
Fabio Pizza, Juliane Winkelmann, Poul Jennum, Sona Nevsimalova, Tim M. Strom, Fang Han, Michael N. Mindrinos, Stine Knudsen, Ling Lin, Chunlin Wang, Farbod Babrzadeh, Hanna Ollila, Marcelo A. Fernandez Viña, Cristin Coquillard, Giuseppe Plazzi, Barbara Schormair, Emmanuel Mignot
Publikováno v:
Sleep 37, 1601-1608 (2014)
Study Objectives: To identify rare allelic variants and HLA alleles in narcolepsy patients with hypocretin (orexin, HCRT) deficiency but lacking DQB1*06:02. Settings: China (Peking University People's Hospital), Czech Republic (Charles University), D
Autor:
Michael Haagenson, Salyka Sengsayadeth, Michael R. Verneris, Madan Jagasia, Marcelo A. Fernandez Viña, Stephanie J. Lee, Stephen R. Spellman, Tao Wang, Carlheinz Müller, Bipin N. Savani
Publikováno v:
Biology of Blood and Marrow Transplantation. 20(6):900-903
Cytotoxic T-lymphocyte antigen-4 (CTLA-4) plays an essential role in T cell homeostasis by restraining immune responses. AG and GG genotypes of donor CTLA-4 SNP rs4553808 in patients after unrelated donor hematopoietic stem cell transplantations (HSC
Autor:
Richard M. Single, Jill A. Hollenbach, Kirsten E. Lyke, Marcelo A. Fernandez Viña, Martin Maiers, Marcelo B. Sztein, Chaim Brautbar, Kai Cao, Glenys Thomson, Peter Stastny, William Klitz, Shosahna Israel, Pedro Cano, M. E. Moraes, Eduardo Raimondi, Steven J. Mack, Evelyne Khoriaty, Manuela Testi, Marco Andreani, Adlette Inati
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 367:820-829
The human leucocyte antigen (HLA) system shows extensive variation in the number and function of loci and the number of alleles present at any one locus. Allele distribution has been analysed in many populations through the course of several decades,