Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Marcelo A. Christoffolete"'
Blockade of caspase cascade overcomes malaria-associated acute respiratory distress syndrome in mice
Autor:
Michelle K. Sercundes, Luana S. Ortolan, Viviane da Silva Julio, Leonardo M. Bella, Thatyane de Castro Quirino, Daniela Debone, Marcela S. Carneiro-Ramos, Marcelo A. Christoffolete, Joilson O. Martins, Maria Regina D’Império Lima, José M. Alvarez, Gustavo P. Amarante-Mendes, Lígia Antunes Gonçalves, Claudio R. F. Marinho, Sabrina Epiphanio
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-10 (2022)
Abstract Malaria is an enormous burden on global health that caused 409,000 deaths in 2019. Severe malaria can manifest in the lungs, an illness known as acute respiratory distress syndrome (ARDS). Not much is known about the development of malaria-a
Externí odkaz:
https://doaj.org/article/b24b45de6cc94b70b577d0208914de04
Autor:
Sandra C. Souza, Marcelo A. Christoffolete, Miriam O. Ribeiro, Hideaki Miyoshi, Katherine J. Strissel, Zlatina S. Stancheva, Nicole H. Rogers, Tara M. D'Eon, James W. Perfield, II, Hitomi Imachi, Martin S. Obin, Antonio C. Bianco, Andrew S. Greenberg
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 6, Pp 1273-1279 (2007)
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis). NE-induced lipolysis is m
Externí odkaz:
https://doaj.org/article/acf6a4bb370d4311994c2d085ee15e66
Autor:
Talita Monsores Paixão, Carlos Eduardo Gomes Siqueira, Elisa Tristan-Cheever, Frida Marina Fischer, Maria Carmen Martinez, Marcelo Augusto Christoffolete, Kirsten Meisinger, Liliane Reis Teixeira
Publikováno v:
Obesity Facts (2023)
Introduction: Obesity is considered a growing public health problem by the Brazilian Ministry of Health and a global epidemic by the World Health Organization (WHO). In 2020, the Centers for Disease Control and Prevention (CDC) estimated the prevalen
Externí odkaz:
https://doaj.org/article/af818e26887e4fbaae646c29b0af969d
Autor:
Fernando A. de Oliveira, Lindomar J. C. Albuquerque, Michelle Nascimento-Sales, Marcelo A. Christoffolete, Ismael C. Bellettini, Fernando C. Giacomelli
Publikováno v:
Journal of Materials Chemistry B. 11:4556-4571
This investigation highlights that ocular and hepatic gene delivery can be potentialized by using small hydrophobic moieties along with lactose domains, and principally, succinic acid conjugated to polyethylenimine chains.
Autor:
Gilvania Barreto Feitosa Coutinho, Maria de Fátima Ramos Moreira, Frida Marina Fischer, Maria Carolina Reis dos Santos, Lucas Ferreira Feitosa, Sayonara Vieira de Azevedo, Renato Marçullo Borges, Michelle Nascimento-Sales, Marcelo Augusto Christoffolete, Marden Samir Santa-Marinha, Daniel Valente, Liliane Reis Teixeira
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 20; Issue 6; Pages: 4760
Objective: To evaluate the association between environmental exposure to the following chemical substances: cadmium (Cd), lead (Pb), nickel (Ni), manganese (Mn), benzene (BZN), and toluene (TLN), and Period Circadian Regulator 3 (PER3) gene variable
Autor:
Ben Kent, Margareth K.K.D. Franco, Christiane Bertachini Lombello, Marcelo A. Christoffolete, Mônica H. M. Nascimento, Débora Carajiliascov Ferraraz, Michelle Nascimento-Sales, Fabiano Yokaichiya, Samyr Machado Querobino, Carlos Alberto-Silva, Hermann Windisch-Neto, Felipe Nogueira Ambrosio, Daniele Ribeiro de Araujo
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 128
Sulforaphane (SFN) is an isothiocyanate with anti-arthritic and immuno-regulatory activities, supported by the downregulation of NF-κB pathway, reduction on metalloproteinases expression and prevention of cytokine-induced cartilage degeneration impl
Publikováno v:
Physical chemistry chemical physics : PCCP. 23(14)
The control of skin permeability to specific substances (e.g., medications, vitamins, and nutrients) through stratum corneum is a challenge. Iontophoresis is an option in spite of the lack of a detailed understanding of the underlying molecular mecha
Autor:
Fernanda Gaisler-Silva, Marcela Sorelli Carneiro-Ramos, Izabelle Fredo-da-Costa, Carolina Victoria Cruz Junho, Marcelo A. Christoffolete
Publikováno v:
Current molecular medicine. 22(4)
Background: Cardiovascular diseases correspond to the highest risk of sudden death worldwide, and obesity is largely related to be an increased risk factor. There is a higher prevalence of arterial hypertension in obese individuals, including the pre
Autor:
Marcela Sorelli Carneiro-Ramos, Marcelo A. Christoffolete, Karina Kaori Nakama, Samuel Santos Beserra, Mayra Trentin Sonoda, Danilo Roman-Campos, Carolina Victoria Cruz Junho, Karine Panico
Publikováno v:
Transplantation proceedings. 52(10)
Ischemic renal failure is an inflammatory disease that can affect various organs, including the heart. The organ responds to the stimulus and undergoes tissue remodeling that can result in cardiac hypertrophy. This study aimed to characterize the car
Autor:
Amílcar Sabino Damazo, Nair Honda Kawashita, Valéria Ernestânia Chaves, Laís A.A. Ferreira, Mayara Peron Pereira, Flávia H.S. da Silva, Marcelo A. Christoffolete, Andreas D. Flouris, Suélem Aparecida de França, George S. Metsios
Publikováno v:
Nutrition. 42:37-45
Objective The aim of this study was to evaluate the browning and origin of fatty acids (FAs) in the maintenance of triacylglycerol (TG) storage and/or as fuel for thermogenesis in perirenal adipose tissue (periWAT) and inguinal adipose tissue (ingWAT