Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Marcelo, Ezquer"'
Autor:
Cristian De Gregorio, Javiera Gallardo, Pablo Berríos-Cárcamo, Álex Handy, Daniela Santapau, Antonia González-Madrid, Marcelo Ezquer, Paola Morales, Alejandro Luarte, Daniela Corvalán, Úrsula Wyneken, Fernando Ezquer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Methadone is a synthetic long-acting opioid that is increasingly used in the replacement therapy of opioid-addicted patients, including pregnant women. However, methadone therapy in this population poses challenges, as it induces cognitive a
Externí odkaz:
https://doaj.org/article/c97e278c93b2462fbcf4cc37be181850
Autor:
Eduardo Durán-Jara, Matías del Campo, Valentina Gutiérrez, Ignacio Wichmann, César Trigo, Marcelo Ezquer, Lorena Lobos-González
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-19 (2024)
Abstract Background Tumor-derived small extracellular vesicles (sEVs) can promote tumorigenic and metastatic capacities in less aggressive recipient cells mainly through the biomolecules in their cargo. However, despite recent advances, the specific
Externí odkaz:
https://doaj.org/article/be31d396aeff4141bb645788b1dd9bb9
Autor:
Cristian De Gregorio, Evelyng Catalán, Gabriel Garrido, Pilar Morandé, Jimena Castillo Bennett, Catalina Muñoz, Glenda Cofré, Ya-Lin Huang, Bárbara Cuadra, Paola Murgas, Margarita Calvo, Fernando Altermatt, María Joao Yubero, Francis Palisson, Andrew P. South, Marcelo Ezquer, Ignacia Fuentes
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-16 (2023)
Abstract Background Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a rare inherited skin disease caused by variants in the COL7A1 gene, coding for type VII collagen (C7), an important component of anchoring fibrils in the basement membrane of t
Externí odkaz:
https://doaj.org/article/a8dd191f66034a75a30a05ba91bc6a46
Autor:
María Elena Quintanilla, Mauricio Quezada, Paola Morales, Pablo Berríos-Cárcamo, Daniela Santapau, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Fernando Ezquer
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The present study investigates the possible therapeutic effects of human mesenchymal stem cell-derived secretome on morphine dependence and relapse. This was studied in a new model of chronic voluntary morphine intake in Wistar rats which sh
Externí odkaz:
https://doaj.org/article/ed7ee41ada154597b45eb68a4b078348
Autor:
Barbara Cuadra, Veronica Silva, Ya-Lin Huang, Yael Diaz, Claudio Rivas, Cristobal Molina, Valeska Simon, Maria Rosa Bono, Bernardo Morales, Mario Rosemblatt, Sebastian Silva, Rodrigo Acuña, Fernando Ezquer, Marcelo Ezquer
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2073 (2024)
Acute-on-chronic liver failure (ACLF) is a syndrome marked by sudden liver function decline and multiorgan failure, predominantly acute kidney injury (AKY), in patients with chronic liver disease. Unregulated inflammation is a hallmark of ACLF; howev
Externí odkaz:
https://doaj.org/article/f8e4c0f647664b4fab61ba74bf9d2c82
Autor:
María Elena Quintanilla, Paola Morales, Daniela Santapau, Alba Ávila, Carolina Ponce, Pablo Berrios-Cárcamo, Belén Olivares, Javiera Gallardo, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Fernando Ezquer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17081 (2023)
Chronic opioid intake leads to several brain changes involved in the development of dependence, whereby an early hedonistic effect (liking) extends to the need to self-administer the drug (wanting), the latter being mostly a prefrontal–striatal fun
Externí odkaz:
https://doaj.org/article/488b0fae56d3491abaff5aaa83d7e949
Autor:
Matias Mugnaini, Diana Polania, Yannina Diaz, Marcelo Ezquer, Fernando Ezquer, Robert M. J. Deacon, Patricia Cogram, Emilio Kropff
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The Octodon degus is a South American rodent that is receiving increased attention as a potential model of aging and sporadic late-onset Alzheimer’s disease (AD). Impairments in spatial memory tasks in Octodon degus have been reported in r
Externí odkaz:
https://doaj.org/article/495e7d45e4dc417c892dacd7bb1a3553
Autor:
Michael J. Hurley, Claudio Urra, B. Maximiliano Garduno, Agostino Bruno, Allison Kimbell, Brent Wilkinson, Cristina Marino-Buslje, Marcelo Ezquer, Fernando Ezquer, Pedro F. Aburto, Elie Poulin, Rodrigo A. Vasquez, Robert Deacon, Ariel Avila, Francisco Altimiras, Peter Whitney Vanderklish, Guido Zampieri, Claudio Angione, Gabriele Constantino, Todd C. Holmes, Marcelo P. Coba, Xiangmin Xu, Patricia Cogram
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
The degu (Octodon degus) is a diurnal long-lived rodent that can spontaneously develop molecular and behavioral changes that mirror those seen in human aging. With age some degu, but not all individuals, develop cognitive decline and brain pathology
Externí odkaz:
https://doaj.org/article/e09a35f5fb5646e3af0bc630bdc8e841
Autor:
Cristian De Gregorio, David Contador, Diego Díaz, Constanza Cárcamo, Daniela Santapau, Lorena Lobos-Gonzalez, Cristian Acosta, Mario Campero, Daniel Carpio, Caterina Gabriele, Marco Gaspari, Victor Aliaga-Tobar, Vinicius Maracaja-Coutinho, Marcelo Ezquer, Fernando Ezquer
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-21 (2020)
Abstract Background Diabetic polyneuropathy (DPN) is the most common and early developing complication of diabetes mellitus, and the key contributor for foot ulcers development, with no specific therapies available. Different studies have shown that
Externí odkaz:
https://doaj.org/article/b981a8d586ed427395898de3d6642625
Autor:
Ya-Lin Huang, Cristian De Gregorio, Verónica Silva, Álvaro A. Elorza, Patricio Léniz, Víctor Aliaga-Tobar, Vinicius Maracaja-Coutinho, Mauricio Budini, Fernando Ezquer, Marcelo Ezquer
Publikováno v:
Cells, Vol 12, Iss 4, p 636 (2023)
Drug-induced liver injury (DILI) is one of the leading causes of acute liver injury. While many factors may contribute to the susceptibility to DILI, obese patients with hepatic steatosis are particularly prone to suffer DILI. The secretome derived f
Externí odkaz:
https://doaj.org/article/6dbc88ad9d7d4f1b865cba8147c2dc71