Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Marcello Gaudiano"'
Autor:
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M. Fernando, Nicholas Kwiatkowski, Rosella Marullo, M. Nieves Calvo-Vidal, Jude Phillip, Benet Pera, Shao Ning Yang, Kaipol Takpradit, Lidia Roman, Marcello Gaudiano, Ramona Crescenzo, Jia Ruan, Giorgio Inghirami, Tinghu Zhang, Graciela Cremaschi, Nathanael S. Gray, Leandro Cerchietti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
T-cell lymphomas are aggressive diseases associated with poor outcome. Here, the authors show that the THZ1, a CDK7 inhibitor, suppresses STAT transcriptional activity leading to apoptosis and sensitization to BCL2 inhibitors in T-cell lymphomas.
Externí odkaz:
https://doaj.org/article/d9b0eca4497a40c1b2e964a28298864d
Autor:
Francesco Guerrera, Fabrizio Tabbò, Luca Bessone, Francesca Maletta, Marcello Gaudiano, Elisabetta Ercole, Laura Annaratone, Maria Todaro, Monica Boita, Pier Luigi Filosso, Paolo Solidoro, Luisa Delsedime, Alberto Oliaro, Anna Sapino, Enrico Ruffini, Giorgio Inghirami
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145100 (2016)
INTRODUCTION:Bio-repositories are invaluable resources to implement translational cancer research and clinical programs. They represent one of the most powerful tools for biomolecular studies of clinically annotated cohorts, but high quality samples
Externí odkaz:
https://doaj.org/article/af8be027fd954ccda01fbd4147ac4f0c
Autor:
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M. Fernando, Nicholas Kwiatkowski, Rossella Marullo, M. Nieves Calvo-Vidal, Jude Phillip, Benet Pera, Shao Ning Yang, Kaipol Takpradit, Lidia Roman, Marcello Gaudiano, Ramona Crescenzo, Jia Ruan, Giorgio Inghirami, Tinghu Zhang, Graciela Cremaschi, Nathanael S Gray, Leandro Cerchietti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14290 (2017); Published: 30 January 2017; Updated: 20 February 2017 The original version of this Article contained an error in the spelling of the author Rossella Marullo, which was incorrectly given as Rosell
Externí odkaz:
https://doaj.org/article/4f6d287b1b314c20bd2687a9811a5e95
Autor:
Mark S. Tichenor, John J. M. Wiener, Navin L. Rao, Genesis M. Bacani, Jianmei Wei, Charlotte Pooley Deckhut, J. Kent Barbay, Kevin D. Kreutter, Leon Chang, Kathleen W. Clancy, Heather E. Murrey, Weixue Wang, Kay Ahn, Michael Huber, Elizabeth Rex, Kevin J. Coe, Jiejun Wu, Haopeng Rui, Kia Sepassi, Marcello Gaudiano, Mariette Bekkers, Ivo Cornelissen, Kathryn Packman, Mark Seierstad, Christos Xiouras, Scott D. Bembenek, Richard Alexander, Cynthia Milligan, Sriram Balasubramanian, Alec D. Lebsack, Jennifer D. Venable, Ulrike Philippar, James P. Edwards, Gavin Hirst
Publikováno v:
Journal of Medicinal Chemistry. 65:14326-14336
Bruton's tyrosine kinase (BTK) is a Tec family kinase that plays an essential role in B-cell receptor (BCR) signaling as well as Fcγ receptor signaling in leukocytes. Pharmacological inhibition of BTK has been shown to be effective in treating hemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b6932f837c19dc6e82c72e8534354a
https://doi.org/10.1021/acs.jmedchem.2c01026
https://doi.org/10.1021/acs.jmedchem.2c01026
Autor:
Anna Sapino, Giorgio Inghirami, Fabrizio Tabbò, Marcello Gaudiano, Francesco Guerrera, Enrico Ruffini, Alessia Nottegar, Luisa Delsedime, Riet Hilhorst, Luca Bessone, Francesca Maletta, Adrienne van den Berg, Rik de Wijn, Rob Ruijtenbeek, Lorena Costardi
Publikováno v:
European journal of cancer (Oxford, England : 1990). 144
Introduction High fidelity between non–small cell lung cancer (NSCLC) primary tumours and patient-derived tumour xenografts (PDTXs) is of paramount relevance to spur their application. Extensive proteomic and kinomic analysis of these preclinical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4d59cb81e5fae2232271c5d9c809ef
https://pubmed.ncbi.nlm.nih.gov/33316635
https://pubmed.ncbi.nlm.nih.gov/33316635
Autor:
Giovannino Ciccone, Francesca Maletta, Anna Sapino, Pier Luigi Filosso, Nicola Veronese, Francesco Guerrera, Alberto Oliaro, Fabrizio Tabbò, Marcello Gaudiano, Claudio Luchini, Enrico Ruffini, Giorgio Inghirami, Luisa Delsedime, Licia Montagna, Filomena Di Giacomo, Alessia Nottegar, Aldo Scarpa, Marco Chilosi, Enrica Migliore
Publikováno v:
Human Pathology. 75:167-178
Strong prognostic markers able to stratify lung adenocarcinoma (ADC) patients are lacking. We evaluated whether a six-immunohistochemical markers panel (TTF1, SP-A, Napsin A, MUC5AC, CDX2 and CK5), defining the putative neoplastic “cell of origin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa93cee7a0e31bcad1df7a3410dd6e9c
https://doi.org/10.1016/j.humpath.2018.01.017
https://doi.org/10.1016/j.humpath.2018.01.017
Autor:
Ulrike Philippar, Lorena Fontan, Ivo Cornelissen, Haopeng Rui, Sriram Balasubramanian, Marcello Gaudiano, Mariette Bekkers, Luc Van Nuffel, Tianbao Lu, John Wiener, Mark Tichenor, Tony Greway, Kathryn Packman, Bie Verbist, Yusri Elsayed, Ricardo Attar, Jacqueline Bussolari, John Gerecitano
Publikováno v:
Cancer Research. 81:1267-1267
Background: Constitutive activation of the classical nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) pathway is a clear driver of B-cell non-Hodgkin lymphomas (NHL). Bruton's Tyrosine Kinase (BTK) and Mucosa-associated lymphoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f55cce1586407af620b6db9d9bf1555
https://doi.org/10.1158/1538-7445.am2021-1267
https://doi.org/10.1158/1538-7445.am2021-1267
Autor:
Yann Abraham, Bart Petrus Anna Maria Jozef Medaer, Weimei Sun, Greet Vanhoof, Haopeng Rui, Yusri Elsayed, Sriram Balasubramanian, Ulrike Philippar, Marcello Gaudiano, Jan Willem Thuring, Jenna D. Goldberg, Tianbao Lu, Jennifer Smit, Peter J. Connolly, James P. Edwards, Max Cummings, Emanuele Trella, John Gerecitano, Nele Vloemans, Ricardo Attar, Tony Greway, Katarzyna Wnuk-Lipinska, Jan Linders, Kristof Kimpe, Amy J. Johnson, Jaqueline Bussolari, Bas-jan van der Leede, Luc Van Nuffel, Mariette Bekkers, Katie Amssoms
Publikováno v:
Blood Cancer Discovery. 1:PO-49
Introduction: Constitutive activation of the classical nuclear factor kappa-light-chain-enhancer of activated B cells (NF κB) pathway is a clear driver of B-cell lymphomas, especially the aggressive activated B-cell (ABC) subtype of diffuse large B-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e8109699ae1dad100496dfd36f4ec75
https://doi.org/10.1158/2643-3249.lymphoma20-po-49
https://doi.org/10.1158/2643-3249.lymphoma20-po-49
Autor:
Ulrike Philippar, Tianbao Lu, Nele Vloemans, Mariette Bekkers, Luc Van Nuffel, Marcello Gaudiano, Katarzyna Wnuk-Lipinska, Bas-jan Van Der Leede, Katie Amssoms, Kristof Kimpe, Bart Medaer, Tony Greway, Yann Abraham, Max Cummings, Emanuele Trella, Greet Vanhoof, Weimei Sun, Jan Willem Thuring, Peter Connolly, Jan Linders, Haopeng Rui, Sriram Balasubramanian, Amy Johnson, John Gerecitano, Jenna Goldberg, James P. Edwards, Yusri Elsayed, Jennifer Smit, Jaqueline Bussolari, Ricardo Attar
Publikováno v:
Cancer Research. 80:5690-5690
Introduction: Constitutive activation of the classical nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) pathway is a clear driver of B-cell lymphomas, especially the aggressive activated B-cell (ABC) subtype of diffuse large B-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504dd7a5e5c4ecf52e6e466854e7daea
https://doi.org/10.1158/1538-7445.am2020-5690
https://doi.org/10.1158/1538-7445.am2020-5690
Autor:
Leandro Cerchietti, Florencia Cayrol, Kaipol Takpradit, Tinghu Zhang, Pannee Praditsuktavorn, Graciela Cremaschi, Rossella Marullo, Tharu M. Fernando, Marcello Gaudiano, Nicholas Kwiatkowski, Nathanael S. Gray, Jude M. Phillip, Giorgio Inghirami, M. Nieves Calvo-Vidal, Lidia Roman, Benet Pera, Jia Ruan, Shao Ning Yang, Ramona Crescenzo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14290 (2017); Published: 30 January 2017; Updated: 20 February 2017 The original version of this Article contained an error in the spelling of the author Rossella Marullo, which was incorrectly given as Rosell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09a55bb4aba47dc45d5be1a4eb128cb
https://doi.org/10.1038/ncomms14747
https://doi.org/10.1038/ncomms14747