Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Marcello Curvietto"'
Autor:
Maria Antonietta Isgrò, Maria Grazia Vitale, Egidio Celentano, Flavia Nocerino, Giuseppe Porciello, Marcello Curvietto, Domenico Mallardo, Concetta Montagnese, Luigi Russo, Nicoletta Zanaletti, Antonio Avallone, Matilde Pensabene, Michelino De Laurentiis, Sara Centonze, Sandro Pignata, Lucia Cannella, Alessandro Morabito, Francesco Caponigro, Gerardo Botti, Giuseppe Valentino Masucci, Diana Giannarelli, Ernesta Cavalcanti, Paolo Antonio Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-6 (2021)
Abstract Coronavirus disease 2019 (COVID-19) global pandemic has created unique challenges to healthcare systems throughout the world. Ensuring subjects’ safety is mandatory especially in oncology, in consideration of cancer patients’ particular
Externí odkaz:
https://doaj.org/article/1f5e064f521c4075a09670221c9524d3
Autor:
Ester Simeone, Giosuè Scognamiglio, Mariaelena Capone, Diana Giannarelli, Antonio M. Grimaldi, Domenico Mallardo, Gabriele Madonna, Marcello Curvietto, Assunta Esposito, Fabio Sandomenico, Francesco Sabbatino, Nicholas L. Bayless, Sarah Warren, SuFey Ong, Gerardo Botti, Keith T. Flaherty, Soldano Ferrone, Paolo A. Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background Studies carried out in vitro and in a mouse model have shown that BRAF inhibitors enhance the effects of IFN-α on BRAFV600E melanoma cells through the inhibition of ERK. Therefore, the combination of vemurafenib and IFN-α in pat
Externí odkaz:
https://doaj.org/article/86e55258d57a4fdc9a2470824a69f5e9
Autor:
Gabriele Madonna, Silvia Sale, Mariaelena Capone, Chiara De Falco, Valentina Santocchio, Tiziana Di Matola, Giuseppe Fiorentino, Caterina Pirozzi, Anna D’Antonio, Rocco Sabatino, Lidia Atripaldi, Umberto Atripaldi, Marcello Raffone, Marcello Curvietto, Antonio Maria Grimaldi, Vito Vanella, Lucia Festino, Luigi Scarpato, Marco Palla, Michela Spatarella, Francesco Perna, Pellegrino Cerino, Gerardo Botti, Roberto Parrella, Vincenzo Montesarchio, Paolo Antonio Ascierto, Luigi Atripaldi
Publikováno v:
Biology, Vol 10, Iss 8, p 735 (2021)
In December 2019, a novel coronavirus, “SARS-CoV-2”, was recognized as the cause of coronavirus disease 2019 (COVID-19). Several studies have explored the changes and the role of inflammatory cells and cytokines in the immunopathogenesis of the d
Externí odkaz:
https://doaj.org/article/e343bdff7d1d4b32b0340e0b82d59d55
Autor:
Emilio Francesco Giunta, Gianluca Arrichiello, Marcello Curvietto, Annalisa Pappalardo, Davide Bosso, Mario Rosanova, Anna Diana, Pasqualina Giordano, Angelica Petrillo, Piera Federico, Teresa Fabozzi, Sara Parola, Vittorio Riccio, Brigitta Mucci, Vito Vanella, Lucia Festino, Bruno Daniele, Paolo Antonio Ascierto, Margaret Ottaviano, On Behalf of SCITO YOUTH
Publikováno v:
Cells, Vol 10, Iss 8, p 2048 (2021)
Cutaneous melanoma is a lethal disease, even when diagnosed in advanced stages. Although recent progress in biology and treatment has dramatically improved survival rates, new therapeutic approaches are still needed. Deregulation of epigenetics, whic
Externí odkaz:
https://doaj.org/article/a9511d94ca3d4c90b062bf095cfca61f
Autor:
Giacomo Pascarella, Arturo Capasso, Antonio Nardone, Maria Triassi, Sandro Pignata, Laura Arenare, Paolo Ascierto, Marcello Curvietto, Piera Maiolino, Roberta D'Aniello, Agnese Montanino, Francesca Laudato, Gianfranco De Feo, Gerardo Botti, Francesco Perrone, Antonella Petrillo, Ernesta Cavalcanti, Secondo Lastoria, Nicola Maurea, Alessandro Morabito
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210330 (2019)
AimThe aim of the present study was to assess the estimated "per patient" total cost for a single Oncologic Italian Cancer Center participating in a multicenter clinical trial with new anticancer biological agents using the activity-based costing (AB
Externí odkaz:
https://doaj.org/article/56b60e557d7249d98acd2f419d2dfc17
Autor:
Margaret Ottaviano, Emilio Francesco Giunta, Marianna Tortora, Marcello Curvietto, Laura Attademo, Davide Bosso, Cinzia Cardalesi, Mario Rosanova, Pietro De Placido, Erica Pietroluongo, Vittorio Riccio, Brigitta Mucci, Sara Parola, Maria Grazia Vitale, Giovannella Palmieri, Bruno Daniele, Ester Simeone, on behalf of SCITO YOUTH
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3474 (2021)
As widely acknowledged, 40–50% of all melanoma patients harbour an activating BRAF mutation (mostly BRAF V600E). The identification of the RAS–RAF–MEK–ERK (MAP kinase) signalling pathway and its targeting has represented a valuable milestone
Externí odkaz:
https://doaj.org/article/fa83fa831ea34f988d2caaed6fb49d42
Autor:
Ester Simeone, Antonio Maria Grimaldi, Lucia Festino, Diana Giannarelli, Vito Vanella, Marco Palla, Marcello Curvietto, Assunta Esposito, Giuseppe Palmieri, Nicola Mozzillo, Paolo Antonio Ascierto
Publikováno v:
OncoImmunology, Vol 6, Iss 3 (2017)
The optimal sequencing of targeted treatment and immunotherapy in the treatment of advanced melanoma is a key question and prospective studies to address this are ongoing. Previous observations suggest that treating first with targeted therapy may se
Externí odkaz:
https://doaj.org/article/027e718b8ac44ecdb255d7ef91281a4a
Autor:
Paolo A. Ascierto, Mario Mandalà, Pier Francesso Ferrucci, Massimo Guidoboni, Piotr Rutkowski, Virginia Ferraresi, Ana Arance, Michele Guida, Evaristo Maiello, Helen Gogas, Erika Richtig, Maria Teresa Fierro, Celeste Lebbè, Hildur Helgadottir, Paola Queirolo, Francesco Spagnolo, Marco Tucci, Michele Del Vecchio, Maria Gonzales Cao, Alessandro Marco Minisini, Sabino De Placido, Miguel F. Sanmamed, Domenico Mallardo, Marcello Curvietto, Ignacio Melero, Giuseppe Palmieri, Antonio M. Grimaldi, Diana Giannarelli, Reinhard Dummer, Vanna Chiarion Sileni
Publikováno v:
Journal of Clinical Oncology. 41:212-221
PURPOSE Limited prospective data are available on sequential immunotherapy and BRAF/MEK inhibition for BRAFV600-mutant metastatic melanoma. METHODS SECOMBIT is a randomized, three-arm, noncomparative phase II trial (ClinicalTrials.gov identifier: NCT
Autor:
N. Zanaletti, Sara Centonze, Paolo A. Ascierto, Alessandro Morabito, Egidio Celentano, Maria Antonietta Isgrò, Marcello Curvietto, Gerardo Botti, Francesco Caponigro, Giuseppe Masucci, Flavia Nocerino, Diana Giannarelli, Michelino De Laurentiis, Ernesta Cavalcanti, Luigi Russo, Maria Grazia Vitale, Matilde Pensabene, Sandro Pignata, Antonio Avallone, Domenico Mallardo, Concetta Montagnese, Giuseppe Porciello, Lucia Cannella
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-6 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Coronavirus disease 2019 (COVID-19) global pandemic has created unique challenges to healthcare systems throughout the world. Ensuring subjects’ safety is mandatory especially in oncology, in consideration of cancer patients’ particular frailty.
Autor:
Paolo A. Ascierto, Antonio M. Grimaldi, Ester Simeone, Vito Vanella, Claudia Trojaniello, Marcello Curvietto, Lucia Festino, Maria Vitale
Publikováno v:
Expert Review of Respiratory Medicine. 14:5-13
Introduction: Treatment of extensive-stage SCLC is still a challenge but immunotherapy with checkpoint inhibitors is showing promising results. Nivolumab alone or in combination with ipilimumab has demonstrated a benefit in terms of response and surv