Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Marcello Arsura"'
Autor:
Marcello Arsura, Snorri S. Thorgeirsson, Amer A. Beg, Frank Mercurio, Insa Schroeder, Swayamjot Kaur, Valentina M. Factor, Manickam Venkatraman, Lakita G. Cavin
Supplementary Figure Legends from Regulation of α-Fetoprotein by Nuclear Factor-κB Protects Hepatocytes from Tumor Necrosis Factor-α Cytotoxicity during Fetal Liver Development and Hepatic Oncogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593da30ce445ed11796c8fe3133b2ab6
https://doi.org/10.1158/0008-5472.22363817
https://doi.org/10.1158/0008-5472.22363817
Autor:
Marcello Arsura, Snorri S. Thorgeirsson, Amer A. Beg, Frank Mercurio, Insa Schroeder, Swayamjot Kaur, Valentina M. Factor, Manickam Venkatraman, Lakita G. Cavin
Nuclear factor-κB (NF-κB) plays a critical role during fetal liver development and hepatic oncogenesis. Here, we have assessed whether NF-κB activity is required for murine hepatocellular carcinoma cell survival. We show that adenoviral-mediated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f75d91e8a4b51f7b1231051f6fe62c4
https://doi.org/10.1158/0008-5472.c.6493910
https://doi.org/10.1158/0008-5472.c.6493910
Autor:
Marcello Arsura, Snorri S. Thorgeirsson, Amer A. Beg, Frank Mercurio, Insa Schroeder, Swayamjot Kaur, Valentina M. Factor, Manickam Venkatraman, Lakita G. Cavin
Supplementary Discussion from Regulation of α-Fetoprotein by Nuclear Factor-κB Protects Hepatocytes from Tumor Necrosis Factor-α Cytotoxicity during Fetal Liver Development and Hepatic Oncogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a458eff2d933a6812e8c1416ba09fe
https://doi.org/10.1158/0008-5472.22363820
https://doi.org/10.1158/0008-5472.22363820
Autor:
Leonard R. Johnson, Ryoko Tsukahara, Veeresa Gududuru, Duane D. Miller, Louisa Balazs, E. Shuyu, Gabor Tigyi, Lester VanMiddlesworth, William J. Valentine, Gangadhar Durgam, Venkatraman Manickam, Wenlin Deng, Abby L. Parrill, Marcello Arsura
Publikováno v:
Gastroenterology. 132:1834-1851
Background & Aims: We recently identified lysophosphatidic acid (LPA) as a potent antiapoptotic agent for the intestinal epithelium. The objective of the present study was to evaluate the effect of octadecenyl thiophosphate (OTP), a novel rationally
Autor:
Lakita G. Cavin, Marcello Arsura
Publikováno v:
Cancer Letters. 229:157-169
Hepatocellular carcinoma (HCC) is the third deadliest and fifth most common human cancer worldwide. Hepatitis C virus (HCV) and hepatitis B virus (HBV) infections along with alcohol and aflatoxin B1 intake are widely recognized etiological agents in
Autor:
Marcello Arsura, Fang Wang, Manickam Venkatraman, Lakita G. Cavin, Valentina M. Factor, Snorri S. Thorgeirsson, Swayamjot Kaur
Publikováno v:
Molecular Cancer Research. 3:403-412
Nuclear factor-kappaB (NF-kappaB) plays an important role during liver neoplastic development through transcriptional regulation of prosurvival genes, which then counteract the death-inducing signals elicited by the host immune response. The c-Myc pr
Autor:
Manickam Venkatraman, Lakita G. Cavin, Marcello Arsura, Snorri S. Thorgeirsson, Frank Mercurio, Amer A. Beg, Valentina M. Factor, Insa S. Schroeder, Swayamjot Kaur
Publikováno v:
Cancer Research. 64:7030-7038
Nuclear factor-κB (NF-κB) plays a critical role during fetal liver development and hepatic oncogenesis. Here, we have assessed whether NF-κB activity is required for murine hepatocellular carcinoma cell survival. We show that adenoviral-mediated i
Autor:
Ganesh R. Panta, Lakita G. Cavin, Mervyn Israel, Jennifer D. Bilyeu, Trevor W. Sweatman, Leonard Lothstein, Christina M. Barrett, Marcello Arsura, Eddie J. Turner
Publikováno v:
Molecular Pharmacology. 65:1038-1047
Nuclear factor kappaB (NF-kappaB) has been implicated in inducible chemoresistance against anthracyclines. In an effort to improve the cytotoxicity of anthracyclines while reducing their cardiotoxic effects, we have developed a novel class of extranu
Autor:
Snorri S. Thorgeirsson, Marcello Arsura, Aundrea L. Oliver, Gail E. Sonenshein, Valentina M. Factor, Ganesh R. Panta
Publikováno v:
Hepatology. 34:32-41
NF-kappaB regulates liver cell death during development, regeneration, and neoplastic transformation. For example, we showed that oncogenic Ras- or Raf-mediated transformation of rat liver epithelial cells (RLEs) led to altered NF-kappaB regulation t
Autor:
Stefania Pianetti, Marcello Arsura, Robert J. Coffey, Raphaëlle Romieu-Mourez, Gail E. Sonenshein
Publikováno v:
Oncogene. 20:1287-1299
The Nuclear Factor (NF)-kappaB family of transcription factors controls expression of genes which promote cell growth, survival, and neoplastic transformation. Recently we demonstrated aberrant constitutive activation of NF-kappaB in primary human an