Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Marcelle Silva-Abreu"'
Autor:
Marcelle Silva-Abreu, Lilian Sosa, Lupe Carolina Espinoza, María-José Fábrega, María J. Rodríguez-Lagunas, Mireia Mallandrich, Ana Cristina Calpena, María Luisa Garduño-Ramírez, María Rincón
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2403 (2023)
Apremilast (APM) is a novel drug for the treatment of psoriasis and psoriatic arthritis. APM is a phosphodiesterase 4 (PDE4) inhibitor, raising intracellular cAMP levels and thereby decreasing the inflammatory response by modulating the expression of
Externí odkaz:
https://doaj.org/article/fd0ee155877647a491ecb7e2f557e3b2
Autor:
Negar Ahmadi, María Rincón, Marcelle Silva-Abreu, Lilian Sosa, Jessica Pesantez-Narvaez, Ana Cristina Calpena, María J. Rodríguez-Lagunas, Mireia Mallandrich
Publikováno v:
Gels, Vol 9, Iss 6, p 448 (2023)
Pranoprofen (PRA)-loaded nanostructured lipid carriers (NLC) have been dispersed into blank gels composed of 1% of Carbomer 940 (PRA-NLC-Car) and 3% of Sepigel® 305 (PRA-NLC-Sep) as a novel strategy to refine the biopharmaceutical profile of PRA, fo
Externí odkaz:
https://doaj.org/article/658ba4d3d38240dc91d84638a6603cbc
Autor:
Roya Mohammadi-Meyabadi, Negar Beirampour, Núria Garrós, Helen Lissette Alvarado, David Limón, Marcelle Silva-Abreu, Ana Cristina Calpena, Mireia Mallandrich
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2714 (2022)
The low water solubility of baricitinib (BCT) limits the development of new formulations for the topical delivery of the drug. The aims of this study were to assess the solubility of BCT in different solvents, including Transcutol, a biocompatible pe
Externí odkaz:
https://doaj.org/article/0af623fa519349f3a1f34b2772287463
Autor:
María Rincón, Lupe Carolina Espinoza, Marcelle Silva-Abreu, Lilian Sosa, Jessica Pesantez-Narvaez, Guadalupe Abrego, Ana Cristina Calpena, Mireia Mallandrich
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1185 (2022)
Transmucosal delivery is commonly used to prevent or treat local diseases. Pranoprofen is an anti-inflammatory drug prescribed in postoperative cataract surgery, intraocular lens implantation, chorioretinopathy, uveitis, age-related macular degenerat
Externí odkaz:
https://doaj.org/article/da8b7fc3b50044f5bbdd615e82fd897a
Autor:
María Rincón, Marcelle Silva-Abreu, Lupe Carolina Espinoza, Lilian Sosa, Ana Cristina Calpena, María J. Rodríguez-Lagunas, Helena Colom
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 22 (2021)
A biocompatible topical thermo-reversible hydrogel containing Pranoprofen (PF)-loaded nanostructured lipid carriers (NLCs) was studied as an innovative strategy for the topical treatment of skin inflammatory diseases. The PF-NLCs-F127 hydrogel was ch
Externí odkaz:
https://doaj.org/article/675eb5fb5eb54ae2ab2aca8cf8343eb3
Autor:
Marcelle Silva-Abreu, Esther Miralles, Christina S. Kamma-Lorger, Marta Espina, María Luisa García, Ana Cristina Calpena
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1751 (2021)
Pioglitazone-loaded PLGA-PEG nanoparticles (NPs) were stabilized by the spray drying technique as an alternative to the treatment of ocular inflammatory disorders. Pioglitazone-NPs were developed and characterized physiochemically. Interaction studie
Externí odkaz:
https://doaj.org/article/d7ca8b97131d4958a765b3db5b28d90a
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 650 (2021)
Pioglitazone (PGZ) is an oral anti-hyperglycemic agent, belongs to the class of thiazolidinediones, and is used for the treatment of diabetes mellitus type 2. In recent years, its anti-inflammatory activity has also been demonstrated in the literatur
Externí odkaz:
https://doaj.org/article/441c5dc6ba74480d894dfc404a29dcd6
Autor:
Paulo Sarango-Granda, Marcelle Silva-Abreu, Ana Cristina Calpena, Lyda Halbaut, María-José Fábrega, María J. Rodríguez-Lagunas, Natalia Díaz-Garrido, Josefa Badia, Lupe Carolina Espinoza
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 484 (2020)
Apremilast (APR) is a selective phosphodiesterase 4 inhibitor administered orally in the treatment of moderate-to-severe plaque psoriasis and active psoriatic arthritis. The low solubility and permeability of this drug hinder its dermal administratio
Externí odkaz:
https://doaj.org/article/c66cb5421e9144ce8df93acfef4d823e
Autor:
Lupe Carolina Espinoza, Rodrigo Vera-García, Marcelle Silva-Abreu, Òscar Domènech, Josefa Badia, María J. Rodríguez-Lagunas, Beatriz Clares, Ana Cristina Calpena
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 255 (2020)
Pioglitazone (PGZ) is a drug used to treat type 2 diabetes mellitus that has been reported to show additional therapeutic activities on diverse inflammatory parameters. The aim of this study was to optimize a topical PGZ-loaded nanoemulsion (PGZ-NE)
Externí odkaz:
https://doaj.org/article/7ad156f428b449d78b20f0d638e51966
Autor:
Lilian Sosa, Ana Cristina Calpena, Marcelle Silva-Abreu, Lupe Carolina Espinoza, María Rincón, Nuria Bozal, Oscar Domenech, María José Rodríguez-Lagunas, Beatriz Clares
Publikováno v:
Pharmaceutics, Vol 11, Iss 7, p 312 (2019)
The present study was designed to develop a thermoreversible gel of Pluronic (P407) loaded amphotericin B (AmB-gel) for the dermal and vaginal treatment of candidiasis. P407 was used as a copolymer to exploit potential advantages related to increasin
Externí odkaz:
https://doaj.org/article/b209d35de1c54f30862afe65646079ee