Výsledky vyhledávání - "Marcella Rezende Rodrigues"

Akademický článek

Selection strategy of phage-displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infection

Autor: Fernanda Fonseca Ramos, Lourena Emanuele Costa, Daniel Silva Dias, Thaís Teodoro Oliveira Santos, Marcella Rezende Rodrigues, Daniela Pagliara Lage, Beatriz Cristina Silveira Salles, Vívian Tamietti Martins, Patrícia Aparecida Fernandes Ribeiro, Miguel Angel Chávez-Fumagalli, Ana Carolina Silva Dias, Patrícia Terra Alves, Érica Leandro Marciano Vieira, Bruno Mendes Roatt, Daniel Menezes-Souza, Mariana Costa Duarte, Antonio Lúcio Teixeira, Luiz Ricardo Goulart, Eduardo Antonio Ferraz Coelho

Publikováno v: Parasites & Vectors, Vol 10, Iss 1, Pp 1-14 (2017)

Abstract Background The development of a vaccine for the prevention of visceral leishmaniasis (VL) still represents a significant unmet medical need. A human vaccine can be found if one takes into consideration that many people living in endemic area

Externí odkaz: https://doaj.org/article/48239a0af8084c31b3c8386503360883

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Selection strategy of phage-displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infection

Autor: Miguel A. Chávez-Fumagalli, Antônio Lúcio Teixeira, Vívian T. Martins, Fernanda F. Ramos, Mariana C. Duarte, Thaís T.O. Santos, Beatriz C.S. Salles, Daniel Menezes-Souza, Ana C. S. Dias, Lourena E. Costa, Patrícia A.F. Ribeiro, Eduardo A.F. Coelho, Bruno Mendes Roatt, Daniela P. Lage, Érica Leandro Marciano Vieira, Luiz Ricardo Goulart, Daniel Dias, Marcella Rezende Rodrigues, Patrícia Terra Alves

Publikováno v: Parasites & Vectors, Vol 10, Iss 1, Pp 1-14 (2017)
Parasites & Vectors

Background The development of a vaccine for the prevention of visceral leishmaniasis (VL) still represents a significant unmet medical need. A human vaccine can be found if one takes into consideration that many people living in endemic areas of dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a265afb735c605c88f15068553c21377
http://link.springer.com/article/10.1186/s13071-017-2576-8

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Antileishmanial activity and mechanism of action from a purified fraction of Zingiber officinalis Roscoe against Leishmania amazonensis

Autor: Daniela P. Lage, Diogo G. Valadares, Tatiana G. Ribeiro, Letícia Martins dos Reis Lage, André Augusto Gomes Faraco, Marcella Rezende Rodrigues, Miguel Angel Chávez Fumagalli, Eduardo Silva, Rachel Oliveira Castilho, Carlos Alberto Pereira Tavares, João Paulo Viana Leite, Jamil S. Oliveira, Manuel Soto, Mariana C. Duarte, Eduardo A.F. Coelho, Grasiele S.V. Tavares

Publikováno v: LOCUS Repositório Institucional da UFV
Universidade Federal de Viçosa (UFV)
instacron:UFV

In recent years, considerable attention has been given to identify new antileishmanial products derived from medicinal plants, although, to date, no new effective compound has been recently applied to treat leishmaniasis. In the present study, the an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46dbc16d108703b27669d0e48fa9b4c9
https://doi.org/10.1016/j.exppara.2016.03.026

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Avaliação da proteína Prohibitina de Leishmania infantum como biomarcador para o diagnóstico sorológico das leishmanioses

Autor: Marcella Rezende Rodrigues

Publikováno v: Repositório Institucional da UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG

CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior As leishmanioses são doenças de alta morbidade e mortalidade, endêmicas no Brasil, causadas por parasitos do gênero Leishmania. Os testes sorológicos atuais dessas doenças

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::8b5ba9fa33a8534d62f44112cfcd1277

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Recombinant prohibitin protein of Leishmania infantum acts as a vaccine candidate and diagnostic marker against visceral leishmaniasis

Publikováno v: Cellular immunology. 323

Visceral leishmaniasis (VL) represents a serious public health problem, as Leishmania infantum is one of main disease causative agents in the Americas. In a previous immunoproteomic study, the prohibitin (PHB) protein was identified in L. infantum pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0169d8ca42a014cf658f892b708a0ff
https://pubmed.ncbi.nlm.nih.gov/29128045

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Immunodiagnosis of human and canine visceral leishmaniasis using recombinant Leishmania infantum Prohibitin protein and a synthetic peptide containing its conformational B-cell epitope

Autor: Ricardo Andrez Machado de Ávila, Carolina K. Miyazaki, Mariana C. Duarte, Eduardo A.F. Coelho, Bruno Mendes Roatt, Vívian T. Martins, Lucas M.O. Santos, Paula Melo de Abreu Vieira, Amanda Christine Da Silva Kursancew, Fernanda F. Ramos, Fernanda Ludolf, Daniel Menezes-Souza, Daniel Dias, Marcella Rezende Rodrigues, Denise Utsch Gonçalves, Jamil S. Oliveira

Publikováno v: Journal of Immunological Methods. 474:112641

In the present study, Leishmania infantum's Prohibitin was cloned and, alongside a synthetic peptide, evaluated for the serodiagnosis of visceral and tegumentary leishmaniasis (CVL and TL, respectively) in dogs and humans. For TL diagnosis, this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd40b2ba8e24e7a19b4450e35c0bc3d
https://doi.org/10.1016/j.jim.2019.112641

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An 8-hydroxyquinoline-containing polymeric micelle system is effective for the treatment of murine tegumentary leishmaniasis

Autor: Letícia Martins dos Reis Lage, Marcella Rezende Rodrigues, Débora V.C. Mendonça, Daniel Menezes-Souza, Eduardo A.F. Coelho, Jose Mario Barichello, Bruno Mendes Roatt, Ricardo José Alves, Ana Maria Ravena Severino Carvalho, Daniela P. Lage, Mariana C. Duarte, Carlos Alberto Pereira Tavares

Publikováno v: Parasitology research. 115(11)

The current treatment of leishmaniasis has been hampered due to the high toxicity of the available drugs and long duration protocols, which often lead to its abandonment. In the present study, a poloxamer 407-based delivery system was developed, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3c17d931051f40d263c97d2123a611
https://pubmed.ncbi.nlm.nih.gov/27365053

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A new Leishmania-specific hypothetical protein, LiHyT, used as a vaccine antigen against visceral leishmaniasis

Autor: Miguel A. Chávez-Fumagalli, Daniela P. Lage, Carlos Alberto Pereira Tavares, Bruno Mendes Roatt, Vívian T. Martins, Daniel Menezes-Souza, Eduardo A.F. Coelho, Manuel Soto, Mariana C. Duarte, Marcella Rezende Rodrigues, Esther Garde, Lourena E. Costa

Publikováno v: Acta tropica. 154

The present study aimed to evaluate a new Leishmania-specific hypothetical protein, LiHyT, as a vaccine candidate against VL. The immunogenicity of the recombinant protein (rLiHyT) plus saponin was evaluated in BALB/c mice. In the results, it is show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24c59d1017384c9848c9f1689a66afa
https://pubmed.ncbi.nlm.nih.gov/26593442

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