Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marcella E. O'Reilly"'
Autor:
Marcella E. O’Reilly, Sebastian Ho, Johana Coronel, Lucie Zhu, Wen Liu, Chenyi Xue, Eunyoung Kim, Esther Cynn, Caio V. Matias, Rajesh Kumar Soni, Chen Wang, Iuliana Ionita-Laza, Robert C. Bauer, Leila Ross, Yiying Zhang, Silvia Corvera, Susan K. Fried, Muredach P. Reilly
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114240- (2024)
Summary: Adipose tissue remodeling and dysfunction, characterized by elevated inflammation and insulin resistance, play a central role in obesity-related development of type 2 diabetes (T2D) and cardiovascular diseases. Long intergenic non-coding RNA
Externí odkaz:
https://doaj.org/article/577c9a29704b4b8ca143497013362bb5
Autor:
Sarina Kajani, Sean Curley, Marcella E. O'Reilly, Xiaofei Yin, Eugene T. Dillon, Weili Guo, Kanishka N. Nilaweera, Lorraine Brennan, Helen M. Roche, Fiona C. McGillicuddy
Publikováno v:
Molecular Metabolism, Vol 56, Iss , Pp 101425- (2022)
Introduction: High-fat diet (HFD)-induced obesity impairs clearance of cholesterol through the Reverse Cholesterol Transport (RCT) pathway, with downregulation in hepatic expression of cholesterol and bile acid transporters, namely ABCG5/8 and ABCB11
Externí odkaz:
https://doaj.org/article/9a74e5c821be49dc9efd9343bc31251f
Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
Autor:
Robyn Bruen, Sean Curley, Sarina Kajani, Daniel Crean, Marcella E. O’Reilly, Margaret B. Lucitt, Catherine G. Godson, Fiona C. McGillicuddy, Orina Belton
Publikováno v:
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-13 (2017)
Abstract Background Macrophages play a pivotal role in atherosclerotic plaque development. Recent evidence has suggested the glucagon-like peptide-1 receptor (GLP-1R) agonist, liraglutide, can attenuate pro-inflammatory responses in macrophages. We h
Externí odkaz:
https://doaj.org/article/660410bee8c34ce48687fcbb5137dfe3
Autor:
Esther Cynn, Daniel Y. Li, Marcella E. O’Reilly, Ying Wang, Alexander C. Bashore, Anjali Jha, Andrea S. Foulkes, Hanrui Zhang, Hanna Winter, Lars Maegdefessel, Hanying Yan, Mingyao Li, Leila Ross, Chenyi Xue, Muredach P. Reilly
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:286-299
Background: Long noncoding RNAs (lncRNAs) have emerged as novel regulators of macrophage biology and inflammatory cardiovascular diseases. However, studies focused on lncRNAs in human macrophage subtypes, particularly human lncRNAs that are not conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e9df0ec755c04cb2e175ba91aa5d5f
https://doi.org/10.1161/atvbaha.122.318353
https://doi.org/10.1161/atvbaha.122.318353
Autor:
Esther, Cynn, Daniel, Li, Marcella E, O'Reilly, Ying, Wang, Alexander C, Bashore, Anjali, Jha, Andrea, Foulkes, Hanrui, Zhang, Hanna, Winter, Lars, Maegdefessel, Hanying, Yan, Mingyao, Li, Leila, Ross, Chenyi, Xue, Muredach P, Reilly
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology.
Long noncoding RNAs (lncRNAs) have emerged as novel regulators of macrophage biology and inflammatory cardiovascular diseases. However, studies focused on lncRNAs in human macrophage subtypes, particularly human lncRNAs that are not conserved in rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fa3eacb2239bbbc1ccde3d43e6d2a71
https://pubmed.ncbi.nlm.nih.gov/36546321
https://pubmed.ncbi.nlm.nih.gov/36546321
Autor:
Marcella E O'Reilly, Wen Liu, Chenyi Xue, Esther Cynn, Lucie Zhu, Leila Ross, Muredach P Reilly
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: Dysfunctional adipose tissue (AT), characterized by increased inflammation and immune cell recruitment, plays a central role in the development of T2DM and atherosclerotic CVDs. LincRNAs are important emerging regulators of cellular funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4386bdc85a382db80b27e90baa3e3bdf
https://doi.org/10.1161/atvb.42.suppl_1.432
https://doi.org/10.1161/atvb.42.suppl_1.432
Autor:
Tingyi Cao, Marcella E. O’Reilly, Caitlin Selvaggi, Esther Cynn, Heidi Lumish, Chenyi Xue, Anjali Jha, Muredach P. Reilly, Andrea S. Foulkes
Publikováno v:
J Hum Genet
Many complex disease risk loci map to intergenic regions containing long intergenic noncoding RNAs (lincRNAs). The majority of these is not conserved outside humans, raising the question whether genetically regulated expression of non-conserved and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a6a1a475db970d1594a51cf8b554a9
https://europepmc.org/articles/PMC9038657/
https://europepmc.org/articles/PMC9038657/
Autor:
Sarina Kajani, Sean Curley, Marcella E. O'Reilly, Xiaofei Yin, Eugene T. Dillon, Weili Guo, Kanishka N. Nilaweera, Lorraine Brennan, Helen M. Roche, Fiona C. McGillicuddy
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 56, Iss, Pp 101425-(2022)
Molecular Metabolism, Vol 56, Iss, Pp 101425-(2022)
Introduction High-fat diet (HFD)-induced obesity impairs clearance of cholesterol through the Reverse Cholesterol Transport (RCT) pathway, with downregulation in hepatic expression of cholesterol and bile acid transporters, namely ABCG5/8 and ABCB11,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd64a6ca0d0d390204b0035129b8ef9
http://europepmc.org/articles/PMC8762459
http://europepmc.org/articles/PMC8762459
Autor:
Anne-Marie Howe, Sinéad Burke, Marcella E. O’Reilly, Fiona C. McGillicuddy, Derek A. Costello
Publikováno v:
Molecular neurobiology. 59(4)
The relationship between systemic immunity and neuroinflammation is widely recognised. Infiltration of peripheral immune cells to the CNS during certain chronic inflammatory states contributes significantly to neuropathology. Obesity and its co-morbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381f9d4c50a1d0713e5c959602eb6e29
https://pubmed.ncbi.nlm.nih.gov/35079937
https://pubmed.ncbi.nlm.nih.gov/35079937