Zobrazeno 1 - 10 of 238 pro vyhledávání: '"Marcella, Mottolese"'
1
Akademický článek
TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients
Autor: Roberto Dinami, Manuela Porru, Carla Azzurra Amoreo, Isabella Sperduti, Marcella Mottolese, Simonetta Buglioni, Daniele Marinelli, Marcello Maugeri-Saccà, Andrea Sacconi, Giovanni Blandino, Carlo Leonetti, Giuliana Di Rocco, Alessandra Verdina, Francesca Spinella, Francesco Fiorentino, Gennaro Ciliberto, Annamaria Biroccio, Pasquale Zizza
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-13 (2020)
Abstract Background Colorectal cancer is one of most common tumors in developed countries and, despite improvements in treatment and diagnosis, mortality rate of patients remains high, evidencing the urgent need of novel biomarkers to properly identi
Externí odkaz: https://doaj.org/article/767fa99324964b889013aba888fd2d7a
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2
Akademický článek
PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes
Autor: Rossano Lattanzio, Manuela Iezzi, Gianluca Sala, Nicola Tinari, Marco Falasca, Saverio Alberti, Simonetta Buglioni, Marcella Mottolese, Letizia Perracchio, Pier Giorgio Natali, Mauro Piantelli
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Phospholipase Cγ1 (PLCγ1) is highly expressed in human tumours. Our previous studies reported that both stable and inducible PLCγ1 down-regulation can inhibit formation of breast-cancer-derived experimental lung metastasis. Fur
Externí odkaz: https://doaj.org/article/09d85a4e175849d8b74e5adf2d27f53a
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3
Akademický článek
Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages
Autor: Sara Donzelli, Elisa Milano, Magdalena Pruszko, Andrea Sacconi, Silvia Masciarelli, Ilaria Iosue, Elisa Melucci, Enzo Gallo, Irene Terrenato, Marcella Mottolese, Maciej Zylicz, Alicja Zylicz, Francesco Fazi, Giovanni Blandino, Giulia Fontemaggi
Publikováno v: Breast Cancer Research, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophages tightly control th
Externí odkaz: https://doaj.org/article/a7369b493aa94dc2b68ffa9d49bbb496
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5
Akademický článek
Breast carcinomas with low amplified/equivocal HER2 by Ish: potential supporting role of multiplex ligation-dependent probe amplification
Autor: Cristiana Ercolani, Caterina Marchiò, Anna Di Benedetto, Alessandra Fabi, Letizia Perracchio, Patrizia Vici, Francesca Sperati, Simonetta Buglioni, Vincenzo Arena, Edoardo Pescarmona, Anna Sapino, Irene Terrenato, Marcella Mottolese
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-10 (2017)
Abstract Background This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HE
Externí odkaz: https://doaj.org/article/6f48d14d87de44858c3b5cf68e412716
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6
Akademický článek
Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression
Autor: Anna Di Benedetto, Cristiana Ercolani, Marcella Mottolese, Francesca Sperati, Laura Pizzuti, Patrizia Vici, Irene Terrenato, Abeer M. Shaaban, Matthew P. Humphries, Luigi Di Lauro, Maddalena Barba, Ilio Vitale, Gennaro Ciliberto, Valerie Speirs, Ruggero De Maria, Marcello Maugeri-Saccà
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The ATR-Chk1 and ATM-Chk2 pathways are central in DNA damage repair (DDR) and their over-activation may confer aggressive molecular features, being an adaptive response to endogenous DNA damage and oncogene-induced replication stress. Herein
Externí odkaz: https://doaj.org/article/7b52d76921ce4c5b87a39faf7a697638
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