Výsledky vyhledávání - "Marcell D. Cadney"

DNA Methylation Analysis of Imprinted Genes in the Cortex and Hippocampus of Cross-Fostered Mice Selectively Bred for Increased Voluntary Wheel-Running

Autor: Sarah E. Latchney, Marcell D. Cadney, Austin Hopkins, Theodore Garland

Publikováno v: Behavior Genetics. 52:281-297

We have previously shown that high runner (HR) mice (from a line genetically selected for increased wheel-running behavior) have distinct, genetically based, neurobiological phenotypes as compared with non-selected control (C) mice. However, developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc058653ea83159982f3566fb163e7f3
https://doi.org/10.1007/s10519-022-10112-z

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Weanling gut microbiota composition of a mouse model selectively bred for high voluntary wheel-running behavior

Autor: Monica P. McNamara, Emily M. Venable, Marcell D. Cadney, Alberto A. Castro, Margaret P. Schmill, Lawrence Kazzazi, Rachel N. Carmody, Theodore Garland, Jr

Publikováno v: Journal of Experimental Biology. 226

We compared the fecal microbial community composition and diversity of four replicate lines of mice selectively bred for high wheel-running activity over 81 generations (HR lines) and four non-selected control lines. We performed 16S rRNA gene sequen

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https://doi.org/10.1242/jeb.245081

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Effects of early-life voluntary exercise and fructose on adult activity levels, body composition, aerobic capacity, and organ masses in mice bred for high voluntary wheel-running behavior

Autor: Marcell D. Cadney, Ralph L. Albuquerque, Nicole E. Schwartz, Monica P. McNamara, Alberto A. Castro, Margaret P. Schmill, David A. Hillis, Theodore Garland

Publikováno v: Journal of developmental origins of health and disease.

Fructose (C6H12O6) is acutely obesogenic and is a risk factor for hypertension, cardiovascular disease, and nonalcoholic fatty liver disease. However, the possible long-lasting effects of early-life fructose consumption have not been studied. We test

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https://pubmed.ncbi.nlm.nih.gov/36193024

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Oral antibiotics reduce voluntary exercise behavior in athletic mice

Autor: Monica P. McNamara, Marcell D. Cadney, Alberto A. Castro, David A. Hillis, Kelly M. Kallini, John C. Macbeth, Margaret P. Schmill, Nicole E. Schwartz, Ansel Hsiao, Theodore Garland

Publikováno v: Behav Processes

The gut microbiome can affect various aspects of both behavior and physiology, including exercise ability, but effects on voluntary exercise have rarely been studied. We studied females from a selection experiment in which 4 replicate High Runner (HR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7f3868d8e5cb567f8eecf31f78f11d
https://europepmc.org/articles/PMC9725099/

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Effects of early-life exposure to Western diet and voluntary exercise on adult activity levels, exercise physiology, and associated traits in selectively bred High Runner mice

Autor: Wendy Saltzman, Marcell D. Cadney, Zoe Thompson, Theodore Garland, Ralph Lacerda de Albuquerque, Margaret P. Schmill, Jarren C. Kay, Meng Zhao, Layla Hiramatsu, Jennifer M. Singleton

Publikováno v: Physiol Behav

Exercise behavior is under partial genetic control, but it is also affected by numerous environmental factors, potentially including early-life experiences whose effects persist into adulthood. We studied genetic and early-life environmental effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d7d7a11b904d04e99a764ca6886f69
https://pubmed.ncbi.nlm.nih.gov/33741375

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Early-life effects of juvenile Western diet and exercise on adult gut microbiome composition in mice

Autor: Paul M. Ruegger, Theodore Garland, Marcell D. Cadney, Jennifer M. Singleton, James Borneman, Monica P. McNamara

Publikováno v: J Exp Biol

Alterations to the gut microbiome caused by changes in diet, consumption of antibiotics, etc., can affect host function. Moreover, perturbation of the microbiome during critical developmental periods potentially has long-lasting impacts on hosts. Usi

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https://pubmed.ncbi.nlm.nih.gov/33431595

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Conditioned place preference for cocaine and methylphenidate in female mice from lines selectively bred for high voluntary wheel-running behavior

Autor: Marcell D. Cadney, Theodore Garland, Jocelyn L. Ramirez, Alberto A. Castro, Monica P. McNamara, Layla Hiramatsu, Darrius G. Buenaventura, Zoe Thompson, Ralph Lacerda de Albuquerque, Justin S. Rhodes, Margaret P. Schmill, Jarren C. Kay

Publikováno v: Genes, brain, and behaviorREFERENCES. 20(2)

Behavioral addictions can come in many forms, including overeating, gambling and overexercising. All addictions share a common mechanism involving activation of the natural reward circuit and reinforcement learning, but the extent to which motivation

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https://pubmed.ncbi.nlm.nih.gov/32909333

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Cross-fostering selectively bred High Runner mice affects adult body mass but not voluntary exercise

Autor: Nicole E. Schwartz, Margaret P. Schmill, Marcell D. Cadney, Monica P. McNamara, Alberto A. Castro, David A. Hillis, Theodore Garland

Publikováno v: Physiology & Behavior. 241:113569

While nursing, mammals progress through critical developmental periods for the cardiovascular, musculoskeletal, and central nervous systems. The suckling period in mammals is therefore especially vulnerable to environmental factors that may affect th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bb542136c706e741fbbec98cc01635
https://doi.org/10.1016/j.physbeh.2021.113569

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