Výsledky vyhledávání - "Marcela Stefanini Tsuboy"

Akademický článek

Evaluation of extracts from Coccoloba mollis using the Salmonella/microsome system and in vivo tests

Autor: Marcela Stefanini Tsuboy, Juliana Cristina Marcarini, Dalva Trevisan Ferreira, Elisa Raquel Anastácio Ferraz, Farah Maria Drumond Chequer, Danielle Palma de Oliveira, Lúcia Regina Ribeiro, Mário Sérgio Mantovani

Publikováno v: Genetics and Molecular Biology, Vol 33, Iss 3, Pp 542-548 (2010)

The common everyday use of medicinal plants is an ancient, and still very widespread practice, whereby the need for studies on their possible toxicity and mutagenic properties. The species Coccoloba mollis has been much used in phytotherapy, mainly i

Externí odkaz: https://doaj.org/article/974f2f6044674a36828c89e4b33a0351

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Research Article First cytotoxic, genotoxic, and antigenotoxic assessment of Euterpe oleracea fruit oil (açaí) in cultured human cells

Autor: Edson Luis Maistro, Eduardo de Souza Marques, José Carlos Tavares Carvalho, F. F. Perazzo, Marcela Stefanini Tsuboy, Paulo Cesar Pires Rosa, Isabel Gaivão

Publikováno v: Genetics and Molecular Research. 16

Euterpe oleracea Mart., popularly known as “acai”, is a tropical fruit from the Amazon region where it has considerable economic importance. Acai has been used as food and for several medicinal purposes. Despite the widespread use of this fruit,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::925320e5531236e36c3de527255833a1
https://doi.org/10.4238/gmr16039700

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In Vitro Assessment of Mutagenic And Genotoxic Effects of Coumarin Derivatives 6,7-Dihydroxycoumarin and 4-Methylesculetin

Autor: Edson Luis Maistro, Marcela Stefanini Tsuboy, Flávia Aparecida Resende, Eduardo de Souza Marques, Rafael Palhano Fedato, Chayene de Andrade Cezário da Silva, Flora Tolentino, Eliana Aparecida Varanda

Publikováno v: Journal of Toxicology and Environmental Health, Part A. 78:109-118

Coumarins are naturally occurring compounds, widely distributed throughout the plant kingdom (Plantae), and possess important pharmacological properties, including inhibition of oxidative stress. In this context, newly synthesized coumarin compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f468254633d8d63538dcdfb1f99d3a85
https://doi.org/10.1080/15287394.2014.943865

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Genotoxic, mutagenic and cytotoxic effects of the commercial dye CI Disperse Blue 291 in the human hepatic cell line HepG2

Autor: Mário Sérgio Mantovani, Siegfried Knasmüller, José Pedro Friedmann Angeli, Gisela de Aragão Umbuzeiro, Marcela Stefanini Tsuboy, Lúcia Regina Ribeiro

Publikováno v: Toxicology in Vitro. 21:1650-1655

Textile dyes are discarded into the aquatic ecosystem via industrial effluents and potentially expose humans and local biota to adverse effects. The commercial dye CI Disperse Blue 291 which contains the aminoazobenzene 2-[(2-bromo-4,6-dinitrophenyl)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0529d88fab036203a6ed552282807f
https://doi.org/10.1016/j.tiv.2007.06.020

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Genistein at maximal physiologic serum levels induces G0/G1 arrest in MCF-7 and HB4a cells, but not apoptosis

Autor: Mário Sérgio Mantovani, Marcela Stefanini Tsuboy, Alecsandra Oliveira de Souza, Daniel Junqueira Dorta, Juliana Cristina Marcarini, Lúcia Regina Ribeiro, Natália Aparecida de Paula

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Several studies have demonstrated that a balanced diet can contribute to better human health. For this reason, soy-based food and pure isoflavones (pills) are one of the most consumed. The association of this consumption and lower risks of chronic di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2223b5cdd70f812c9431503eedcc7f
https://pubmed.ncbi.nlm.nih.gov/24325455

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Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions

Autor: Fábio Ferreira Perazzo, Edson Luis Maistro, Ivani Aquino, Mário Sérgio Mantovani, Marcela Stefanini Tsuboy, Juliana Cristina Marcarini

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12f5856487befefce22ece81209d2cf

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Modulação do efeito mutagênico do benzo[a]pireno e bleomicina por extratos de isoflavonas em células de hepatoma de roedor

Autor: Lúcia Regina Ribeiro, Mendes Josiane, Clara Beatriz Hoffman-Campo, Mário Sérgio Mantovani, Marcela Stefanini Tsuboy, Juliana Cristina Marcarini

Publikováno v: Semina: Ciências Biológicas e da Saúde. 33

Estudos epidemiologicos mostram que a ingestao de alimentos ricos em isoflavonas (fitoestrogenos), como a soja, confere protecao contra varios tipos de câncer, o que aumenta o interesse cientifico e popular sobre esses compostos. No presente estudo,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3e067f7725878a2eaba7d0263b42c92
https://doi.org/10.5433/1679-0367.2012v33n1p11

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In vitro evaluation of the genotoxic activity and apoptosis induction of the extracts of roots and leaves from the medicinal plant Coccoloba mollis (Polygonaceae)

Autor: Mário Sérgio Mantovani, Rodrigo Cabral Luiz, Dalva Trevisan Ferreira, Lúcia Regina Ribeiro, Iuri Bezerra de Barros, Marcela Stefanini Tsuboy, Juliana Cristina Marcarini

Publikováno v: Journal of medicinal food. 13(3)

Coccoloba mollis (Family Polygonaceae) is a medicinal plant popularly used in cases of memory loss, stress, insomnia, anemia, impaired vision, and sexual impotence, but the scientific literature, to date, lacks studies on the biological effects of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ee2c5815c9ed1a5e20028a77886557
https://pubmed.ncbi.nlm.nih.gov/20438324

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Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells

Autor: Rodrigo Cabral Luiz, Clara Beatriz Hoffmann-Campo, Marcela Stefanini Tsuboy, Juliana Cristina Marcarini, Mário Ségio Mantovani, Lúcia Regina Ribeiro

Publikováno v: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 63(5)

Rutin is a flavonoid with antioxidant, vasodilatory, anti-inflammatory and immune-stimulating activities. To study the toxicity of rutin and its protective effect, this work investigated the cytotoxic, apoptosis-inducing, genotoxic and protective eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bfdf9b18d4f87f3c51344c758745a8
https://pubmed.ncbi.nlm.nih.gov/20399630

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