Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marcela M.G.B. Dutra"'
Autor:
Elias B. Nascimento, Jr., Thiago R.L. Romero, Marcela M.G.B. Dutra, Bernd L. Fiebich, Igor D.G. Duarte, Márcio M. Coelho
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss , Pp 111210- (2021)
Serotonin (5-HT) acts as a neurotransmitter in the central nervous system (CNS) and as a mediator released by enterochromaffin cells to regulate intestinal motility. However, this amine also plays an important role as an inflammatory mediator and ind
Externí odkaz:
https://doaj.org/article/1381e242e02546fa8d09f80fabedfb3c
Autor:
Felipe F. Rodrigues, Tamires C. Matsui, Carla R.A. Batista, Márcio M. Coelho, Ivo S.F. Melo, Paulo S. A. Augusto, Renes R. Machado, Marcela M.G.B. Dutra, Alysson Vinícius Braga, Sarah O.A.M. Costa, Caryne M. Bertollo, Marcela I. Morais
Publikováno v:
Inflammopharmacology. 30:233-241
Metformin is an oral hypoglycemic drug widely used in the management of type 2 diabetes mellitus. We have recently demonstrated that metformin exhibits activity in models of nociceptive and neuropathic pain. However, little is known about its effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a745b23792bcca50b728a9600263e2cd
https://doi.org/10.1007/s10787-021-00899-4
https://doi.org/10.1007/s10787-021-00899-4
Autor:
Renes R. Machado, Márcio M. Coelho, Ivo S.F. Melo, Marcela M.G.B. Dutra, Adriana M. Godin, Tamires C. Matsui, Wagner G. Canhestro, Ângelo de Fátima, Ana Mercy S. Brito, Ricardo José Alves, Giovanna M.E. Coura, Débora P. Araújo, Carla R.A. Batista
Publikováno v:
Pharmacological Reports. 71:1177-1183
Phthalimide analogues devoid of the glutarimide moiety exhibit multiple biological activities, thus making them candidates for the treatment of patients with different diseases, including those with inflammatory and painful disorders. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae93c2a1cd16bee68f042aa0837bd3e
https://doi.org/10.1016/j.pharep.2019.08.001
https://doi.org/10.1016/j.pharep.2019.08.001
Autor:
Thiago Roberto Lima Romero, Igor D.G. Duarte, Márcio M. Coelho, Marcela M.G.B. Dutra, Bernd L. Fiebich, Elias B. Nascimento
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss, Pp 111210-(2021)
Serotonin (5-HT) acts as a neurotransmitter in the central nervous system (CNS) and as a mediator released by enterochromaffin cells to regulate intestinal motility. However, this amine also plays an important role as an inflammatory mediator and ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee725fd10aeea9ffdd29c2240fd7d965
http://www.sciencedirect.com/science/article/pii/S0753332220314037
http://www.sciencedirect.com/science/article/pii/S0753332220314037
Autor:
Fábio C. Costa, Marcela I. Morais, Ivo S.F. Melo, Paulo S. A. Augusto, Márcio M. Coelho, Ângelo de Fátima, Franciele A. Goulart, Felipe F. Rodrigues, Renes R. Machado, Marcela M.G.B. Dutra, Sarah O.A.M. Costa
Publikováno v:
European Journal of Pharmacology. 824:108-114
Recently, we demonstrated that nicorandil exhibits activities in models of inflammatory and nociceptive pain. In the present study, we extended this investigation by evaluating the effects of nicorandil in models of neuropathic pain induced by paclit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f136a6fe05696b0d39794f6adfc87a
https://doi.org/10.1016/j.ejphar.2018.02.014
https://doi.org/10.1016/j.ejphar.2018.02.014
Autor:
Márcio M. Coelho, Paulo S. A. Augusto, Felipe F. Rodrigues, Fábio C. Costa, Marcela I. Morais, Sarah O.A.M. Costa, Renes R. Machado, Ivo S.F. Melo, Marcela M.G.B. Dutra, Alysson Vinícius Braga, Franciele A. Goulart
Publikováno v:
Inflammopharmacology. 28(2)
Clindamycin, a bacteriostatic semisynthetic lincosamide, is useful in the management of infections caused by aerobic and anaerobic Gram-positive cocci, including bacteremic pneumonia, streptococcal toxic shock syndrome and sepsis. It has been recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97be78cc6d9fdd88dbfc0598054e0ab5
https://pubmed.ncbi.nlm.nih.gov/31768707
https://pubmed.ncbi.nlm.nih.gov/31768707
Autor:
Julliana Ribeiro Alves Santos, Adriana M. Godin, Gerson Antônio Pianetti, Francinely C. Oliveira, Márcio M. Coelho, Débora P. Araújo, Renes R. Machado, Mariana O. Almeida, Raquel R. Menezes, Ângelo de Fátima, Marcela M.G.B. Dutra, Isabela Costa César, Daniel Assis Santos
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:2783-2790
Nicorandil (N-(2-hydroxyethyl)nicotinamide nitrate) is an antianginal drug, which activates guanylyl cyclase and opens the ATP-dependent K(+) channels, actions that have been suggested to mediate its vasodilator activity. We synthesized nicorandil an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1038bbd8b0a091a53b049163acdf6ce5
https://doi.org/10.1016/j.bmc.2014.03.011
https://doi.org/10.1016/j.bmc.2014.03.011
Autor:
Paulo S. A. Augusto, Alysson Vinícius Braga, Sarah O.A.M. Costa, Marcela I. Morais, Renes R. Machado, Márcio M. Coelho, Marcela M.G.B. Dutra, Ivo S.F. Melo, Franciele A. Goulart, Felipe F. Rodrigues, Carla R.A. Batista
Publikováno v:
European Journal of Pharmacology. 858:172497
Metformin, an AMP-activated protein kinase (AMPK) activator, is an oral hypoglycemic drug widely used to treat patients with type 2 diabetes. As AMPK plays a role in the nociceptive processing, investigating the effects induced by metformin in experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de21020fc06b56c9bd11257011c3cfe6
https://doi.org/10.1016/j.ejphar.2019.172497
https://doi.org/10.1016/j.ejphar.2019.172497
Autor:
Renes R. Machado, Marcela M.G.B. Dutra, Júlia D.M. Prazeres, Raquel R. Menezes, Leandro F.S. Bastos, Wallace C. Ferreira, Márcio M. Coelho, Darly G. Soares, Adriana M. Godin
Publikováno v:
Neuroscience Letters. 553:110-114
The research on sex differences in nociception and antinociception as well as sex and gender differences in pain and analgesia is a maturing field. There is a vast literature showing experimental and clinical pain suppressive effects induced by minoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a143ed7c5207dd3bf476ec29ebab72
Autor:
Débora P. Araújo, Leandro F.S. Bastos, João Gabriel T. Seniuk, Elias B. Nascimento, Isabela Costa César, Renes R. Machado, Gerson Antônio Pianetti, Raquel R. Menezes, Márcio M. Coelho, Adriana M. Godin, Wallace C. Ferreira, Darly G. Soares, Ângelo de Fátima, Marcela M.G.B. Dutra
Publikováno v:
Pharmacology Biochemistry and Behavior. 106:85-90
Nicorandil (2-nicotinamide ethyl nitrate), an antianginal drug characterized by the coupling of nicotinamide with a nitric oxide (NO) donor, activates guanylyl cyclase and opens ATP-dependent K(+) channels. In the present study, we investigated the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca42bf4e0a58bb9d2c62996e1a799a7