Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marcela Hortová-Kohoutková"'
Autor:
Ivana Andrejčinová, Gabriela Blažková, Ioanna Papatheodorou, Kamila Bendíčková, Veronika Bosáková, Monika Skotáková, Roman Panovský, Lukáš Opatřil, Ondřej Vymazal, Petra Kovačovicová, Vladimír Šrámek, Martin Helán, Marcela Hortová-Kohoutková, Jan Frič
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25938- (2024)
COVID-19 manifestation is associated with a strong immune system activation leading to inflammation and subsequently affecting the cardiovascular system. The objective of the study was to reveal possible interconnection between prolongated inflammati
Externí odkaz:
https://doaj.org/article/f617ca2ba0344a22bafd2c3c94b44616
Autor:
Marcela Hortová-Kohoutková, Monika Skotáková, Isaac G. Onyango, Miriam Slezáková, Roman Panovský, Lukáš Opatřil, Peter Slanina, Marco De Zuani, Ondřej Mrkva, Ivana Andrejčinová, Petra Lázničková, Martina Dvončová, Alexandra Mýtniková, Vaughn Ostland, Michal Šitina, Gorazd B. Stokin, Vladimír Šrámek, Marcela Vlková, Martin Helán, Jan Frič
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMajor clinically relevant inflammatory events such as septic shock and severe COVID-19 trigger dynamic changes in the host immune system, presenting promising candidates for new biomarkers to improve precision diagnostics and patient stra
Externí odkaz:
https://doaj.org/article/04c0cc079aed47a5a83b613a13f68454
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0c1a4a9ab14b4165addea6d21cdb6b88
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recent findings about the new roles of lactate have changed our understanding of this end product of glycolysis or fermentation that was once considered only a waste product. It is now well accepted that lactate acts as a signaling molecule and fuel
Externí odkaz:
https://doaj.org/article/483d8969fddd468eb274dc2168ba6675
Autor:
Marcela Hortová-Kohoutková, Marco De Zuani, Petra Lázničková, Kamila Bendíčková, Ondřej Mrkva, Ivana Andrejčinová, Alexandra Mýtniková, Ondřej Polanský, Kamila Kočí, Veronika Tomášková, Vladimír Šrámek, Martin Helán, Jan Frič
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Sepsis and septic shock remain leading causes of morbidity and mortality for patients in the intensive care unit. During the early phase, immune cells produce various cytokines leading to prompt activation of the immune system. Polymorphonuclear leuk
Externí odkaz:
https://doaj.org/article/4f0c4bb5dd654f3797c88469645bd791
Autor:
Ondřej Vymazal, Kamila Bendíčková, Marco De Zuani, Marcela Vlková, Marcela Hortová-Kohoutková, Jan Frič
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils are innate immune cells with important roles in antimicrobial defense. However, impaired or dysregulated neutrophil function can result in host tissue damage, loss of homeostasis, hyperinflammation or pathological immunosuppression. A cen
Externí odkaz:
https://doaj.org/article/4fb6bcc966a744eea5089a6259a8d18d
Autor:
Veronika Tomášková, Alexandra Mýtniková, Marcela Hortová Kohoutková, Ondřej Mrkva, Monika Skotáková, Michal Šitina, Kateřina Helánová, Jan Frič, Jiří Pařenica, Vladimír Šrámek, Martin Helán
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Sepsis is a clinical syndrome characterized by a dysregulated response to infection. It represents a leading cause of mortality in ICU patients worldwide. Although sepsis is in the point of interest of research for several decades, its clinical manag
Externí odkaz:
https://doaj.org/article/599daca0805a48cc88ce354abf90785d
Autor:
Veronika Bosáková, Marco De Zuani, Lucie Sládková, Zuzana Garlíková, Shyam Sushama Jose, Teresa Zelante, Marcela Hortová Kohoutková, Jan Frič
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Organoids are complex multicellular three-dimensional (3D) in vitro models that are designed to allow accurate studies of the molecular processes and pathologies of human organs. Organoids can be derived from a variety of cell types, such as human pr
Externí odkaz:
https://doaj.org/article/c03c4fc6ddfc4ab1b6b8e1eff8bf5c23
Autor:
Jan Fric, Vladimír Šrámek, Marco De Zuani, Veronika Tomášková, Marcela Hortová-Kohoutková, Ivana Andrejčinová, Martin Helán
Publikováno v:
European Journal of Immunology
Myeloid‐derived suppressor cells (MDSCs) are important regulators of immune processes during sepsis in mice. However, confirming these observations in humans has been challenging due to the lack of defined preparation protocols and phenotyping sche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bf9d6f50bb880e767a6ddcfeceed40
https://doi.org/10.1002/eji.202049141
https://doi.org/10.1002/eji.202049141
Autor:
Petra Lázničková, Martin Helán, Marco De Zuani, Kamila Bendíčková, Marcela Hortová-Kohoutková, Jan Fric, Vladimír Šrámek, Pavel Suk, Ivana Andrejčinová, Veronika Tomášková
Publikováno v:
Journal of Cellular and Molecular Medicine
Sepsis is characterized by dynamic changes of the immune system resulting in deregulated inflammation and failure of homoeostasis and can escalate to septic shock. Circulating monocytes and other innate immune cells are among the first ones to recogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd22abe86d6039044da7c53d2f406f6
https://doi.org/10.1111/jcmm.15791
https://doi.org/10.1111/jcmm.15791