Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marcela Ferella"'
Autor:
Dimitra Peirasmaki, Showgy Y. Ma’ayeh, Feifei Xu, Marcela Ferella, Sara Campos, Jingyi Liu, Staffan G. Svärd
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Giardia intestinalis colonizes the upper small intestine of humans and animals, causing the diarrheal disease giardiasis. This unicellular eukaryotic parasite is not invasive but it attaches to the surface of small intestinal epithelial cells (IECs),
Externí odkaz:
https://doaj.org/article/ffbcea32643d4da58d1c6e1de3daa2c9
Autor:
Oscar Franzén, Jon Jerlström-Hultqvist, Elin Einarsson, Johan Ankarklev, Marcela Ferella, Björn Andersson, Staffan G Svärd
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 3, p e1003000 (2013)
Giardia intestinalis is a common cause of diarrheal disease and it consists of eight genetically distinct genotypes or assemblages (A-H). Only assemblages A and B infect humans and are suggested to represent two different Giardia species. Correlation
Externí odkaz:
https://doaj.org/article/49648a6c295d4c7fba6a853f0f09a459
Autor:
Oscar Franzén, Erik Arner, Marcela Ferella, Daniel Nilsson, Patricia Respuela, Piero Carninci, Yoshihide Hayashizaki, Lena Aslund, Björn Andersson, Carsten O Daub
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1283 (2011)
The pathway for RNA interference is widespread in metazoans and participates in numerous cellular tasks, from gene silencing to chromatin remodeling and protection against retrotransposition. The unicellular eukaryote Trypanosoma cruzi is missing the
Externí odkaz:
https://doaj.org/article/97eee3fce9e943188af8da3a2191fa2e
Autor:
Suman K Vodnala, Marcela Ferella, Hilda Lundén-Miguel, Evans Betha, Nick van Reet, Daniel Ndem Amin, Bo Oberg, Björn Andersson, Krister Kristensson, Hans Wigzell, Martin E Rottenberg
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 8, p e495 (2009)
BACKGROUND: There is an urgent need to substitute the highly toxic compounds still in use for treatment of the encephalitic stage of human African trypanosomiasis (HAT). We here assessed the treatment with the doublet cordycepin and the deaminase inh
Externí odkaz:
https://doaj.org/article/6636be3df9c7493780dd443fc287610d
Autor:
Kurt Hanevik, Marcela Ferella, Matej Radunovic, Ching M. Liu, Nina Langeland, Elaine M. Hanson, Staffan G. Svärd, Marvin Fischer, Majid Ghassemian, Jonathan Ang, Lars Eckmann, Christine Le, Barbara J. Davids, Yukiko Miyamoto
Publikováno v:
Infection and immunity, vol 87, iss 6
Giardia lamblia, one of the most common protozoal infections of the human intestine, is an important worldwide cause of diarrheal disease, malabsorption, malnutrition, delayed cognitive development in children, and protracted postinfectious syndromes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e707b223e6151083845909603fa80d23
https://pubmed.ncbi.nlm.nih.gov/30962402
https://pubmed.ncbi.nlm.nih.gov/30962402
Publikováno v:
Journal of Biological Chemistry. 283:15884-15892
Trypanosomes are ancient eukaryotic parasites in which the protein-coding genes, organized in large polycistronic clusters on both strands, are transcribed from as yet unidentified promoters. In an effort to reveal transcriptional initiation sites, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5976ddeb6ee82e115552a72f028e6955
https://doi.org/10.1074/jbc.m802081200
https://doi.org/10.1074/jbc.m802081200
Publikováno v:
Experimental Parasitology. 119:308-312
The farnesyl diphosphate synthase (FPPS) has previously been characterized in trypanosomes as an essential enzyme for their survival and as the target for bisphosphonates, drugs that are effective both in vitro and in vivo against these parasites. En
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb2e1e8dcfa301cb2bcf8e1db1d5a9a
https://doi.org/10.1016/j.exppara.2008.02.013
https://doi.org/10.1016/j.exppara.2008.02.013
Autor:
Roberto Docampo, Jacqueline Bua, Marcela Ferella, Silvia Reina, Andrea Montalvetti, Daniel Nilsson, Maria B. Cassera, Peter Rohloff, Esteban J. Bontempi, Makoto Kawamukai, Kildare Miranda, Lena Åslund, Carlos Pravia, Alejandro M. Katzin, Björn Andersson, Jianmin Fang
Publikováno v:
Journal of Biological Chemistry. 281:39339-39348
We report the cloning of a Trypanosoma cruzi gene encoding a solanesyl-diphosphate synthase, TcSPPS. The amino acid sequence (molecular mass approximately 39 kDa) is homologous to polyprenyl-diphosphate synthases from different organisms, showing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82846a2735189517be13709f45aae4f8
https://doi.org/10.1074/jbc.m607451200
https://doi.org/10.1074/jbc.m607451200
Autor:
Daniel Palm, Staffan G. Svärd, Marcela Ferella, Barbara J. Davids, Michael J. Cipriano, Shanda R. Birkeland, Andrew G. McArthur, Frances D. Gillin
Publikováno v:
Molecular and biochemical parasitology. 197(1-2)
Serial Analysis of Gene Expression (SAGE) was used to quantify transcriptional changes in Giardia intestinalis during its interaction with human intestinal epithelial cells (IECs, HT-29) in serum free M199 medium. Transcriptional changes were compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf5ba703ce15b30c0b328be26e83eef
https://pubmed.ncbi.nlm.nih.gov/25286381
https://pubmed.ncbi.nlm.nih.gov/25286381
Autor:
Alicia Graciela Fuchs, Estefanía Poropat, Mónica Inés Esteva, Igal Elingold, Juan B. Rodriguez, Julius Lukeš, Carlos Pravia, Marcela Ferella, De-Hua Lai, Fernando G. Pérez Rojo, Esteban J. Bontempi, Marta Dubin, Malena Landoni, Alicia S. Couto
Ubiquinone 9 (UQ9), the expected product of the long-chain solanesyl diphosphate synthase of Trypanosoma brucei (TbSPPS), has a central role in reoxidation of reducing equivalents in the mitochondrion of T. brucei. The ablation of TbSPPS gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20331c34b68ade57765df7e8d939d80c
http://ec.asm.org/content/13/2/320
http://ec.asm.org/content/13/2/320
