The inflammatory response induced by Pseudomonas aeruginosa in macrophages enhances apoptotic cell removal

Autor: Adriana Valeria Jäger, Paula Arias, Maria Virginia Tribulatti, Marcela Adriana Brocco, Maria Victoria Pepe, Arlinet Kierbel

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract Pathogens phagocytosis and the uptake of apoptotic cells (efferocytosis) are essential macrophages tasks, classically considered as mutually exclusive. Macrophages have been observed to polarize into either pro-inflammatory/microbicidal or a

Externí odkaz: https://doaj.org/article/e11af27c9800490ca7812f0cb33315ab

Neuronal membrane glycoprotein (nmgp‐1) gene deficiency affects chemosensation‐related behaviors, dauer exit and egg‐laying in Caenorhabditis elegans

Autor: Melisa Carolina Monteleone, Yamila B Cutraro, Marcela Adriana Brocco, Alberto C.C. Frasch, Kiley Hughes, Eliana M Fernández, Andrés G. Vidal-Gadea, Jessica Adams

Publikováno v: Journal of Neurochemistry. 160:234-255

The nervous system monitors the environment to maintain homeostasis, which can be affected by stressful conditions. Using mammalian models of chronic stress, we previously observed altered brain levels of GPM6A, a protein involved in neuronal morphol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b889438c83897b012ab5802b477461
https://doi.org/10.1111/jnc.15543

Distinct mechanoreceptor pezo-1 isoforms modulate food intake in the nematode Caenorhabditis elegans

Autor: Shawn Mohammed, Marcela Adriana Brocco, Kiley Hughes, Alyson Ficca, Andrés G. Vidal-Gadea, Ploy Freebairn, Ashka Shah, Rosemary Bauer, Jessica Adams, Emily Harris, Wolfgang Stein, Xiaofei Bai, Chance Bainbridge, Janelle Jackson, Eliana M Fernández

Two PIEZO mechanosensitive cation channels, PIEZO1 and PIEZO2, have been identified in mammals, where they are involved in numerous sensory processes. While structurally similar, PIEZO channels are expressed in distinct tissues and exhibit unique pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79466e743a827537eb5de9ee99de9b82
https://doi.org/10.1101/2021.05.24.445504

Search of brain-enriched proteins in salivary extracellular vesicles for their use as mental disease biomarkers: A pilot study of the neuronal glycoprotein M6a

Autor: Marcela Adriana Brocco, Natalia Catoira, S. Billi, Melisa Carolina Monteleone, Luciano Viale, Alberto C.C. Frasch

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Journal of Affective Disorders Reports, Vol 1, Iss, Pp 100003-(2020)

Background: Mental disorders affect millions of people worldwide. Their etiology is complex and the fact that the main effects occur in the brain hampers biochemical diagnosis. Therefore, biomarker finding in peripheral fluids such as serum or saliva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9809e8154e4bd669129b16dffb149d91
https://linkinghub.elsevier.com/retrieve/pii/S2666915320300032

M6 membrane protein plays an essential role in Drosophila oogenesis.

Autor: María Paula Zappia, Marcela Adriana Brocco, Silvia C Billi, Alberto C Frasch, María Fernanda Ceriani

Publikováno v: PLoS ONE, Vol 6, Iss 5, p e19715 (2011)

We had previously shown that the transmembrane glycoprotein M6a, a member of the proteolipid protein (PLP) family, regulates neurite/filopodium outgrowth, hence, M6a might be involved in neuronal remodeling and differentiation. In this work we focuse

Externí odkaz: https://doaj.org/article/a741b286c1f04f569a598995d0909996