Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Marcela, Pekna"'
Autor:
Giacomo Gravina, Maryam Ardalan, Tetyana Chumak, Anders K. Nilsson, Joakim C. Ek, Hanna Danielsson, Pernilla Svedin, Milos Pekny, Marcela Pekna, Karin Sävman, Ann Hellström, Carina Mallard
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107217- (2023)
Summary: Staphylococcus (S.) epidermidis is the most common nosocomial coagulase-negative staphylococci infection in preterm infants. Clinical signs of infection are often unspecific and novel markers to complement diagnosis are needed. We investigat
Externí odkaz:
https://doaj.org/article/a44cb6ecd6a142a8a294c75645383909
Autor:
Anna Stokowska, Markus Aswendt, Daniel Zucha, Stephanie Lohmann, Frederique Wieters, Javier Morán Suarez, Alison L. Atkins, YiXian Li, Maria Miteva, Julia Lewin, Dirk Wiedermann, Michael Diedenhofen, Åsa Torinsson Naluai, Pavel Abaffy, Lukas Valihrach, Mikael Kubista, Mathias Hoehn, Milos Pekny, Marcela Pekna
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Despite advances in acute care, ischemic stroke remains a major cause of long-term disability. Approaches targeting both neuronal and glial responses are needed to enhance recovery and improve long-term outcome. The complement C3a receptor (C3aR) is
Externí odkaz:
https://doaj.org/article/b09e032290ec4192805c9a19aa899151
Autor:
Malin C. Erlandsson, Karin M.E. Andersson, Nina Y. Oparina, Venkataragavan Chandrasekaran, Tibor Saghy, Anastasios Damdimopoulos, Maria-Jose Garcia-Bonete, Zakaria Einbeigi, Sofia T. Silfverswärd, Marcela Pekna, Gergely Katona, Maria I. Bokarewa
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105526- (2022)
Summary: In this study, we explore the role of nuclear survivin in maintaining the effector phenotype of IFNγ-producing T cells acting through the transcriptional control of glucose utilization. High expression of survivin in CD4+T cells was associa
Externí odkaz:
https://doaj.org/article/28b4f7d719214067a451ac2c22fd36db
Autor:
Lina Bunketorp-Käll, Marcela Pekna, Milos Pekny, Hans Samuelsson, Christian Blomstrand, Michael Nilsson
Publikováno v:
Annals of Rehabilitation Medicine, Vol 44, Iss 5, Pp 362-369 (2020)
Objective To examine the association between observer-assessed functional status and perceived recovery in the late phase after stroke. The study also aimed to determine whether observer-assessed functional improvements as a result of horse-riding th
Externí odkaz:
https://doaj.org/article/0dd8c115eb574814a9e959eb7ed0f83d
Autor:
Andrea Pozo-Rodrigálvarez, YiXian Li, Anna Stokowska, Jingyun Wu, Verena Dehm, Hana Sourkova, Harry Steinbusch, Carina Mallard, Henrik Hagberg, Milos Pekny, Marcela Pekna
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hypoxic-ischemic neonatal encephalopathy due to perinatal asphyxia is the leading cause of brain injury in newborns. Clinical data suggest that brain inflammation induced by perinatal insults can persist for years. We previously showed that signaling
Externí odkaz:
https://doaj.org/article/7eaffa3174164f069d43137e2db8505b
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
As part of the innate immune system, complement plays a critical role in the elimination of pathogens and mobilization of cellular immune responses. In the central nervous system (CNS), many complement proteins are locally produced and regulate nervo
Externí odkaz:
https://doaj.org/article/e0dad2087f47424d9e26f9ed8bfbe655
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b81bbb63f96547db8bf32bb7bd49c8c7
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The C3a receptor (C3aR) is a seven trans-membrane domain G-protein coupled receptor with a range of immune modulatory functions. C3aR is activated by the third complement component (C3) activation derived peptide C3a and a neuropeptide TLQP-21. In th
Externí odkaz:
https://doaj.org/article/c9c0132102414c25a56a09eceb6251c2
Autor:
Marcela Pekna, Milos Pekny
Publikováno v:
Cells, Vol 10, Iss 7, p 1812 (2021)
The complement system, an effector arm of the innate immune system that plays a critical role in tissue inflammation, the elimination of pathogens and the clearance of dead cells and cell debris, has emerged as a regulator of many processes in the ce
Externí odkaz:
https://doaj.org/article/dfeec59ae83e4cbea8c44c1fff3dcb2f
Autor:
Milos Pekny, Ulrika Wilhelmsson, Anna Stokowska, Turgut Tatlisumak, Katarina Jood, Marcela Pekna
Publikováno v:
Cells, Vol 10, Iss 6, p 1537 (2021)
Increased sensitivity of methods assessing the levels of neurofilament light chain (NfL), a neuron-specific intermediate filament protein, in human plasma or serum, has in recent years led to a number of studies addressing the utility of monitoring N
Externí odkaz:
https://doaj.org/article/31f2f38de46c4c9d8197131402ceb981